{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T08:33:22Z","timestamp":1793349202517,"version":"4.5.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:00:00Z","timestamp":1791849600000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32171737"],"award-info":[{"award-number":["32171737"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005046","name":"Natural Science Foundation of Heilongjiang Province","doi-asserted-by":"publisher","award":["ZL2026C005"],"award-info":[{"award-number":["ZL2026C005"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002965","name":"Northeast Forestry University","doi-asserted-by":"publisher","award":["2024A03"],"award-info":[{"award-number":["2024A03"]}],"id":[{"id":"10.13039\/501100002965","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cerasus humilis is a calcium-rich fruit crop with high nutritional value, but its synchronized ripening causes concentrated harvest and a short shelf life. In this study, ChCAX3, a vacuolar cation\/H+ exchanger, was identified as a key regulator of fruit ripening. ChCAX3 showed high expression in fruit and stem tissues and was up-regulated by CaCl2 and ethephon; however, it was repressed during fruit ripening by ChMYB16. ChCAX3 exhibits Ca2+ transport activity, increased tomato fruit Ca2+ content, delayed coloration, reduced softening, and extended the ripening period by \u223c14 d. ChCAX3-mediated vacuolar Ca2+ sequestration may maintain low cytosolic Ca2+ levels, potentially attenuating the expression and activity of a presumptive Ca2+ sensor ChCBL10 and its interacting kinase ChCIPK3 at the vacuolar membrane. This attenuation of the ChCBL10\u2013ChCIPK3 module was accompanied by reduced expression of ethylene biosynthesis genes and cell wall degradation-related genes, which may collectively delay the ethylene burst and preserve fruit firmness. ChMYB16 represses ChCAX3 in late ripening to reverse this process. These findings provide new insights into Ca2+\u2013hormone crosstalk in fruit physiology and identify a potential target for extending shelf life and enhancing nutritional quality.<\/jats:p>","DOI":"10.1093\/jxb\/erag512","type":"journal-article","created":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T11:38:12Z","timestamp":1791718692000},"source":"Crossref","is-referenced-by-count":0,"title":["The cation\/H+ exchanger ChCAX3 fine-tunes fruit ripening by modulating cytosolic Ca2+ homeostasis in\n                    <i>Cerasus humilis<\/i>"],"prefix":"10.1093","author":[{"given":"Qinghua","family":"Shan","sequence":"first","affiliation":[{"name":"State Key Laboratory of Tree Genetics and Breeding, Northeast Forestry University , Harbin, Heilongjiang 150040 ,","place":["China"]},{"name":"College of Life Science, Northeast Forestry University , Harbin, Heilongjiang 150040 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