{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:19:07Z","timestamp":1740136747987,"version":"3.37.3"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T00:00:00Z","timestamp":1707436800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Granulocyte transfusions are indicated for patients with severe neutropenia and evidence of bacterial or fungal infection who are unresponsive to standard antimicrobial therapy. With a limited expiration time of 24 hours after collection, granulocytes are often transfused before results of infectious-disease screening tests are available, and before a transfusion service can perform a risk assessment if postdonation information is provided after the collection. The case we describe herein demonstrates a clinical scenario meeting indications for granulocyte transfusion, coupled with the clinical management undertaken after the granulocyte donor disclosed a positive result for a COVID-19 self-test taken 1 day after donation. In this case, the patient did not develop new COVID-19 symptoms and tested negative for COVID-19 after transfusion of the implicated unit. These findings add to the body of evidence in the literature that COVID-19 is not transmitted via blood transfusion.<\/jats:p>","DOI":"10.1093\/labmed\/lmad118","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T09:09:52Z","timestamp":1707469792000},"page":"524-527","source":"Crossref","is-referenced-by-count":0,"title":["Clinical management of a patient following a granulocyte transfusion from a donor positive for COVID-19"],"prefix":"10.1093","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9189-7885","authenticated-orcid":false,"given":"Jennifer S","family":"Woo","sequence":"first","affiliation":[{"name":"Department of Pathology and City of Hope National Medical Center , Duarte, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2158-5904","authenticated-orcid":false,"given":"Lefan","family":"Zhuang","sequence":"additional","affiliation":[{"name":"Department of Pathology and City of Hope National Medical Center , Duarte, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Jackson","sequence":"additional","affiliation":[{"name":"Department of Pathology and City of Hope National Medical Center , Duarte, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shirong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pathology and City of Hope National Medical Center , Duarte, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vaibhav","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center , Duarte, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Blackmon","sequence":"additional","affiliation":[{"name":"Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center , Duarte, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hoda","family":"Pourhassan","sequence":"additional","affiliation":[{"name":"Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center , Duarte, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Pathology and City of Hope National Medical Center , Duarte, CA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,2,9]]},"reference":[{"issue":"20","key":"2024070305533532500_CIT0001","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1056\/NEJM198105143042001","article-title":"Lethal pulmonary reactions associated with the combined use of amphotericin B and leukocyte transfusions","volume":"304","author":"Wright","year":"1981","journal-title":"N Engl J Med."},{"issue":"6","key":"2024070305533532500_CIT0002","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1046\/j.1537-2995.2000.40060642.x","article-title":"Combined administration of G-CSF and dexamethasone for the mobilization of granulocytes in normal donors: optimization of dosing","volume":"40","author":"Liles","year":"2000","journal-title":"Transfusion."},{"issue":"5","key":"2024070305533532500_CIT0003","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1111\/j.1365-2141.2004.05221.x","article-title":"The role of granulocyte transfusions in neutropenic patients","volume":"127","author":"Bishton","year":"2004","journal-title":"Br J Haematol."},{"author":"AABB","key":"2024070305533532500_CIT0004"},{"issue":"4","key":"2024070305533532500_CIT0005","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1111\/trf.12892","article-title":"Hydroxyethyl starch and granulocyte transfusions: considerations of utility and toxicity profile for patients and donors","volume":"55","author":"Ambruso","year":"2015","journal-title":"Transfusion."},{"issue":"4","key":"2024070305533532500_CIT0006","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1159\/000354093","article-title":"Efficacy and side effects of granulocyte collection in healthy donors","volume":"40","author":"Brockmann","year":"2013","journal-title":"Transfus Med Hemother"},{"edition":"33","volume-title":"Standards for Blood Banks and Transfusion Services","year":"2022","key":"2024070305533532500_CIT0007"},{"edition":"21","volume-title":"Technical Manual.","year":"2023","key":"2024070305533532500_CIT0008"},{"issue":"11","key":"2024070305533532500_CIT0009","doi-asserted-by":"crossref","first-page":"3605","DOI":"10.1182\/blood.V95.11.3605","article-title":"Effect of leukocyte compatibility on neutrophil increment after transfusion of granulocyte colony-stimulating factor\u2013mobilized prophylactic granulocyte transfusions and on clinical outcomes after stem cell transplantation","volume":"95","author":"Adkins","year":"2000","journal-title":"Blood."},{"issue":"21","key":"2024070305533532500_CIT0010","doi-asserted-by":"crossref","first-page":"SCI\u201316","DOI":"10.1182\/blood.V124.21.SCI-16.SCI-16","article-title":"The RING study: a randomized controlled trial of GCSF-stimulated granulocytes in granulocytopenic patients","volume":"124","author":"Price","year":"2014","journal-title":"Blood."},{"issue":"18","key":"2024070305533532500_CIT0011","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1182\/blood-2015-05-645986","article-title":"Efficacy of transfusion with granulocytes from G-CSF\/dexamethasone-treated donors in neutropenic patients with infection","volume":"126","author":"Price","year":"2015","journal-title":"Blood."},{"issue":"5","key":"2024070305533532500_CIT0012","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1111\/trf.14551","article-title":"WBC alloimmunization: effects on the laboratory and clinical endpoints of therapeutic granulocyte transfusions","volume":"58","author":"Price","year":"2018","journal-title":"Transfusion."},{"issue":"1","key":"2024070305533532500_CIT0013","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/01.moh.0000190114.38650.b2","article-title":"Granulocyte transfusion","volume":"13","author":"Atallah","year":"2006","journal-title":"Curr Opin Hematol."},{"issue":"4","key":"2024070305533532500_CIT0014","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.tracli.2021.08.006","article-title":"Post-donation information management","volume":"28","author":"Vuk","year":"2021","journal-title":"Transfus Clin Biol."},{"issue":"1","key":"2024070305533532500_CIT0015","doi-asserted-by":"crossref","first-page":"e0228622","DOI":"10.1128\/spectrum.02286-22","article-title":"Performance evaluation of five rapid at-home COVID-19 antigen tests against the omicron variant","volume":"11","author":"Sugiharto","year":"2023","journal-title":"Microbiol Spectr"},{"year":"2023","author":"Self-Testing at Home or Anywhere","key":"2024070305533532500_CIT0016"},{"year":"2023","author":"Blood Donor History Questionnaires","key":"2024070305533532500_CIT0017"},{"issue":"17","key":"2024070305533532500_CIT0018","doi-asserted-by":"crossref","first-page":"e159876","DOI":"10.1172\/JCI159876","article-title":"Frequent detection but lack of infectivity of SARS-CoV-2 RNA in presymptomatic, infected blood donor plasma","volume":"132","author":"Sa\u00e1","year":"2022","journal-title":"J Clin Invest."},{"issue":"5","key":"2024070305533532500_CIT0019","first-page":"362","article-title":"SARS-CoV-2 and post-donation information: a one-year experience of the French haemovigilance network","volume":"20","author":"Cappy","year":"2022","journal-title":"Blood Transfus"},{"issue":"16","key":"2024070305533532500_CIT0020","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1182\/blood.2020008230","article-title":"No evidence of SARS-CoV-2 transfusion transmission despite RNA detection in blood donors showing symptoms after donation","volume":"136","author":"Cappy","year":"2020","journal-title":"Blood."},{"issue":"11","key":"2024070305533532500_CIT0021","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1016\/j.jiph.2020.05.001","article-title":"COVID-19 transmission and blood transfusion: a case report","volume":"13","author":"Cho","year":"2020","journal-title":"J Infect Public Health"},{"issue":"1","key":"2024070305533532500_CIT0022","doi-asserted-by":"crossref","first-page":"102961","DOI":"10.1016\/j.transci.2020.102961","article-title":"COVID-19: further evidence of no transfusion transmission","volume":"60","author":"Luzzi","year":"2021","journal-title":"Transfus Apher Sci."},{"issue":"2","key":"2024070305533532500_CIT0023","doi-asserted-by":"crossref","first-page":"e28658","DOI":"10.1002\/pbc.28658","article-title":"Lack of transmission of SARS-CoV-2 by platelet transfusion from a COVID-19-positive donor in a hematopoietic stem cell transplantation patient","volume":"68","author":"Essa","year":"2021","journal-title":"Pediatr Blood Cancer."}],"container-title":["Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/labmed\/article-pdf\/55\/4\/524\/58391904\/lmad118.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/labmed\/article-pdf\/55\/4\/524\/58391904\/lmad118.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T05:57:22Z","timestamp":1719986242000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/labmed\/article\/55\/4\/524\/7604165"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,9]]},"references-count":23,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,2,9]]},"published-print":{"date-parts":[[2024,7,3]]}},"URL":"https:\/\/doi.org\/10.1093\/labmed\/lmad118","relation":{},"ISSN":["0007-5027","1943-7730"],"issn-type":[{"type":"print","value":"0007-5027"},{"type":"electronic","value":"1943-7730"}],"subject":[],"published-other":{"date-parts":[[2024,7]]},"published":{"date-parts":[[2024,2,9]]}}}