{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T21:20:14Z","timestamp":1774992014776,"version":"3.50.1"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,3,6]],"date-time":"2024-03-06T00:00:00Z","timestamp":1709683200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Hereditary factor VII (FVII) deficiency is an uncommon autosomal recessive disorder associated with mutations in the F7 gene, and laboratory investigations usually reveal isolated prolongation in prothrombin time (PT)\/international normalized ratio (INR). Venom-induced consumptive coagulopathy (VICC) is distinguished by the activation of the coagulation pathway, which is triggered by procoagulant toxins in snake venom. Diagnosing snakebites in patients with hereditary FVII deficiency presents a challenge because prolonged time PT\/INR is considered the most valuable diagnostic method for VICC. Therefore, it is possible that certain patients may not promptly receive an accurate diagnosis of hereditary FVII deficiency. We present a pedigree featuring hereditary FVII deficiency, which was diagnosed through Sanger sequencing, following a bamboo leaf green snake bite.<\/jats:p>","DOI":"10.1093\/labmed\/lmae012","type":"journal-article","created":{"date-parts":[[2024,1,30]],"date-time":"2024-01-30T23:54:43Z","timestamp":1706658883000},"page":"645-648","source":"Crossref","is-referenced-by-count":1,"title":["The identification of a novel compound heterozygous mutation in hereditary human coagulation factor VII deficiency following a bamboo leaf green snake bite"],"prefix":"10.1093","volume":"55","author":[{"given":"Chuanghua","family":"Qiu","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, Shenzhen Second People\u2019s Hospital Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunxiu","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Shenzhen Second People\u2019s Hospital Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueyan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The People\u2019s Hospital of Longhua Shenzhen , Shenzhen , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dayong","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Shenzhen Second People\u2019s Hospital Shenzhen China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,3,6]]},"reference":[{"issue":"4","key":"2024090405515484700_CIT0001","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1055\/s-0029-1225762","article-title":"Factor FVII deficiency","volume":"35","author":"Mariani","year":"2009","journal-title":"Semin Thromb Hemost."},{"issue":"1","key":"2024090405515484700_CIT0002","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1055\/s-0038-1642646","article-title":"The tissue factor pathway: how it has become a \u201cprima ballerina.\u201d","volume":"74","author":"Rapaport","year":"1995","journal-title":"Thromb Haemost."},{"issue":"10","key":"2024090405515484700_CIT0003","doi-asserted-by":"crossref","first-page":"e3220","DOI":"10.1371\/journal.pntd.0003220","article-title":"Current treatment for venom-induced consumption coagulopathy resulting from snakebite","volume":"8","author":"Maduwage","year":"2014","journal-title":"PLoS NeglTrop Dis."},{"issue":"2","key":"2024090405515484700_CIT0004","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.tmrv.2014.09.005","article-title":"Hematologic effects and complications of snake envenoming","volume":"29","author":"Berling","year":"2015","journal-title":"Transfus Med Rev."},{"issue":"4","key":"2024090405515484700_CIT0005","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3390\/jcm6040038","article-title":"Factor VII deficiency: clinical phenotype, genotype, and therapy","volume":"6","author":"Mariasanta","year":"2017","journal-title":"J Clin Med."},{"issue":"7","key":"2024090405515484700_CIT0006","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1177\/1076029616670257","article-title":"Factor VII deficiency: from basics to clinical laboratory diagnosis and patient management","volume":"23","author":"Pierre-Olivier","year":"2017","journal-title":"Clin Appl Thromb Hemost."},{"issue":"3","key":"2024090405515484700_CIT0007","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1046\/j.1365-2141.2002.03545.x","article-title":"Factor VII deficiency","volume":"118","author":"Perry","year":"2002","journal-title":"Br J Haematol."},{"issue":"4","key":"2024090405515484700_CIT0008","doi-asserted-by":"crossref","first-page":"538","DOI":"10.3324\/haematol.2012.074039","article-title":"Prophylaxis in congenital factor VII deficiency: indications, efficacy, and safety. Results from the Seven Treatment Evaluation Registry (STER)","volume":"98","author":"Napolitano","year":"2013","journal-title":"Haematologica."},{"issue":"6","key":"2024090405515484700_CIT0009","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1111\/j.1538-7836.2007.02435.x","article-title":"The tissue factor-factor VIIa complex: procoagulant activity, regulation, and multitasking","volume":"5","author":"Monroe","year":"2007","journal-title":"J Thromb Haemost."},{"issue":"3","key":"2024090405515484700_CIT0010","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1111\/j.1365-2516.2009.02004.x","article-title":"Familial factor VII deficiency with fetal and neonatal fatal cerebral hemorrhage associated with homozygosis to Gly180Arg mutation","volume":"15","author":"Landau","year":"2009","journal-title":"Hemophilia"},{"issue":"1","key":"2024090405515484700_CIT0011","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/1098-1004(2001)17:1<3::AID-HUMU2>3.0.CO;2-V","article-title":"Factor VII deficiency and the FVII mutation database","volume":"17","author":"McVey","year":"2000","journal-title":"Hum Mutat."},{"issue":"12","key":"2024090405515484700_CIT0012","doi-asserted-by":"crossref","first-page":"4014","DOI":"10.1182\/blood-2003-04-1199","article-title":"Coinheritance of factor V (FV) Leiden enhances thrombin formation and is associated with a mild bleeding phenotype in patients homozygous for the FVII 9726\u00fe5G&gt;A (FVII Lazio) mutation","volume":"102","author":"Castoldi","year":"2003","journal-title":"Blood."},{"issue":"10","key":"2024090405515484700_CIT0013","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1093\/qjmed\/hct102","article-title":"Diagnostic 20 min whole blood clotting test in Russell\u2019s viper envenoming delays antivenom administration","volume":"106","author":"Isbister","year":"2013","journal-title":"QJM."}],"container-title":["Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/labmed\/article-pdf\/55\/5\/645\/58985637\/lmae012.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/labmed\/article-pdf\/55\/5\/645\/58985637\/lmae012.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T19:39:24Z","timestamp":1725478764000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/labmed\/article\/55\/5\/645\/7623491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,6]]},"references-count":13,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,3,6]]},"published-print":{"date-parts":[[2024,9,4]]}},"URL":"https:\/\/doi.org\/10.1093\/labmed\/lmae012","relation":{},"ISSN":["0007-5027","1943-7730"],"issn-type":[{"value":"0007-5027","type":"print"},{"value":"1943-7730","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,9]]},"published":{"date-parts":[[2024,3,6]]}}}