{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T16:57:28Z","timestamp":1790269048286,"version":"4.1.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T00:00:00Z","timestamp":1721606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Hyperviscosity syndrome (HVS) is defined as the symptomatic presentation of increased blood thickness due to various clinical conditions such as hypergammaglobulinemia. HVS secondary to immunoglobulin (Ig)A multiple myeloma has been infrequently reported. Although the efficiency of IgM or IgG removal by therapeutic plasma exchange (TPE) is well described, the efficiency of IgA removal by TPE is not as well known. Here, we describe a case of HVS due to IgA myeloma in a patient who received 2 TPE treatments, with subsequent symptomatic improvement as well as decrease in IgA and viscosity levels.<\/jats:p>","DOI":"10.1093\/labmed\/lmae054","type":"journal-article","created":{"date-parts":[[2024,6,26]],"date-time":"2024-06-26T18:16:13Z","timestamp":1719425773000},"page":"85-88","source":"Crossref","is-referenced-by-count":2,"title":["Therapeutic plasma exchange for hyperviscosity syndrome in IgA multiple myeloma"],"prefix":"10.1093","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7807-6046","authenticated-orcid":false,"given":"Nalan","family":"Yurtsever","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, Yale School of Medicine , New Haven, CT ,","place":["US"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1246-8957","authenticated-orcid":false,"given":"Thomas C","family":"Binns","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Yale School of Medicine , New Haven, CT ,","place":["US"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7928-3132","authenticated-orcid":false,"given":"Jeanne E","family":"Hendrickson","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Emory University School of Medicine and Children\u2019s Healthcare of Atlanta , Atlanta, GA ,","place":["US"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher A","family":"Tormey","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Yale School of Medicine , New Haven, CT ,","place":["US"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1723-4463","authenticated-orcid":false,"given":"Edward 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