{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T04:09:34Z","timestamp":1741666174615,"version":"3.38.0"},"reference-count":4,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:00:00Z","timestamp":1727222400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The anti-double-stranded (ds)DNA antibody test is an integral part of diagnosing systemic lupus erythematosus when the entry criterion is satisfied. We investigated the sensitivity of the BioPlex 2200 instrument compared with the serological gold standard and other tests and clinical information. The results showed an unacceptable sensitivity for this method. Laboratories should be cognizant of this shortcoming when selecting this platform for dsDNA antibody testing.<\/jats:p>","DOI":"10.1093\/labmed\/lmae083","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T17:32:59Z","timestamp":1727285579000},"page":"113-114","source":"Crossref","is-referenced-by-count":0,"title":["Double-stranded DNA antibody test using BioPlex220 system: unacceptable option for SLE diagnosis and follow-up"],"prefix":"10.1093","volume":"56","author":[{"given":"Kamran","family":"Kadkhoda","sequence":"first","affiliation":[{"name":"Immunopathology Laboratory, Robert J. Tomsich Pathology & Laboratory Medicine Department, Diagnostics Institute, Cleveland Clinic , Cleveland, OH ,","place":["US"]},{"name":"Cleveland Clinic Lerner College of Medicine, Case Western Reserve University , Cleveland, OH ,","place":["US"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Immunopathology Laboratory, Robert J. Tomsich Pathology & Laboratory Medicine Department, Diagnostics Institute, Cleveland Clinic , Cleveland, OH ,","place":["US"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Boyert","sequence":"additional","affiliation":[{"name":"Immunopathology Laboratory, Robert J. Tomsich Pathology & Laboratory Medicine Department, Diagnostics Institute, Cleveland Clinic , Cleveland, OH ,","place":["US"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Dee","sequence":"additional","affiliation":[{"name":"Immunopathology Laboratory, Robert J. Tomsich Pathology & Laboratory Medicine Department, Diagnostics Institute, Cleveland Clinic , Cleveland, OH ,","place":["US"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,9,25]]},"reference":[{"issue":"9","key":"2025031011215451500_CIT0001","doi-asserted-by":"publisher","first-page":"1400","DOI":"10.1002\/art.40930","article-title":"2019 European League Against Rheumatism\/American College of Rheumatology classification criteria for systemic lupus erythematosus","volume":"71","author":"Aringer","year":"2019","journal-title":"Arthritis Rheumatol"},{"issue":"3","key":"2025031011215451500_CIT0002","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1007\/s12026-018-8992-9","article-title":"Analytical variability in the determination of anti-double-stranded DNA antibodies: the strong need of a better definition of the old and new tests","volume":"66","author":"Infantino","year":"2018","journal-title":"Immunol Res."},{"issue":"6","key":"2025031011215451500_CIT0003","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1177\/096120339200100606","article-title":"The clinical significance of measuring different anti-dsDNA antibodies by using the Farr assay, an enzyme immunoassay and a Crithidia luciliae immunofluorescence test","volume":"1","author":"Werle","year":"1992","journal-title":"Lupus."},{"issue":"11","key":"2025031011215451500_CIT0004","doi-asserted-by":"publisher","first-page":"3677","DOI":"10.1002\/art.34651","article-title":"Comparison of autoantibody specificities between traditional and bead-based assays in a large, diverse collection of patients with systemic lupus erythematosus and family members","volume":"64","author":"Bruner","year":"2012","journal-title":"Arthritis Rheum."}],"container-title":["Laboratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/labmed\/article-pdf\/56\/2\/113\/59341437\/lmae083.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/labmed\/article-pdf\/56\/2\/113\/59341437\/lmae083.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T11:22:00Z","timestamp":1741605720000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/labmed\/article\/56\/2\/113\/7775418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,25]]},"references-count":4,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,9,25]]},"published-print":{"date-parts":[[2025,3,10]]}},"URL":"https:\/\/doi.org\/10.1093\/labmed\/lmae083","relation":{},"ISSN":["0007-5027","1943-7730"],"issn-type":[{"type":"print","value":"0007-5027"},{"type":"electronic","value":"1943-7730"}],"subject":[],"published-other":{"date-parts":[[2025,3]]},"published":{"date-parts":[[2024,9,25]]}}}