{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T09:09:51Z","timestamp":1769332191272,"version":"3.49.0"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T00:00:00Z","timestamp":1765152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,7]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n To explore the correlation between the expression of Tat interacting protein-30 (TIP30) mRNA in serum of patients with hepatitis B virus (HBV) -derived decompensated liver cirrhosis and recompensation as well as short-term prognosis.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The clinical data of 109 patients with the HBV-related decompensated cirrhosis who were hospitalized in the First Affiliated Hospital of Xi\u2019an Jiaotong University and the First People\u2019s Hospital of Xianyang City from January 2018 to December 2023 were collected and analyzed, retrospectively, including 51 patients who occured recompensation and 58 patients who occured non-recompensation. Serum TIP30 mRNA expression was detected by Real-time polymerase reaction (RT-PCR).<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n An increase in TIP30 mRNA expression after treatment was observed in the recompensation group compared to non-recompensation group (P\u2009&lt;\u20090.001). Our analysis showed that serum TIP30 mRNA expression in the decompensated liver cirrhosis patients was negatively correlated with Child Pugh score, portal vein diameter, spleen length, and the morbidity in ascite, hepatic encephalopathy, hepatorenal syndrome, spontaneous peritonitis, pulmonary infection, and gastrointestinal bleeding (all P\u2009&lt;\u20090.05).<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Detecting serum expression of TIP30 mRNA can provide a basis for evaluating the recompensation and short-term prognosis of decompensated liver cirrhosis. AS shown in .<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/labmed\/lmaf083","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:02:45Z","timestamp":1762520565000},"source":"Crossref","is-referenced-by-count":0,"title":["Correlation analysis of serum TIP30 mRNA expression with recompensation and short-term prognosis in the patients with hepatitis B virus-derived decompensated liver cirrhosis"],"prefix":"10.1093","volume":"57","author":[{"given":"Kai","family":"Deng","sequence":"first","affiliation":[{"name":"Department of Clinical laboratory, the First Affiliated Hospital of Xi\u2019an Jiaotong University , Xi\u2019an City, Shaanxi,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei Juan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Clinical laboratory, the First People\u2019s Hospital of Xianyang City , Xianyang City, Shaanxi,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Cun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Oncology, the First People\u2019s Hospital of Xianyang City , Xianyang City, Shaanxi,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasonic medicine, the First People\u2019s Hospital of Xianyang City , Xianyang City, Shaanxi,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,12,8]]},"reference":[{"key":"2026012412523127200_lmaf083-B1","doi-asserted-by":"publisher","first-page":"100925","DOI":"10.1016\/j.lana.2024.100925","article-title":"Alignment of countries in the Americas with the latest WHO guidelines for hepatitis B virus (HBV) infection: a 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