{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T16:28:21Z","timestamp":1772641701550,"version":"3.50.1"},"reference-count":21,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Education Fund Item of Liaoning Province","award":["LJKMZ20221843"],"award-info":[{"award-number":["LJKMZ20221843"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Autoimmune bullous diseases (AIBDs) are rare, tissue-specific autoimmune diseases of the skin, and corresponding autoantibodies have been proved to be pathogenic. Recently, we reported that variations in platelet-related parameters may reflect the fluctuations of circulating AIBD-correlated antibody titers during the disease progression of 1 patient with AIBD. The purpose of this article is to further investigate the possible correlation between autoantibody titers and platelet-related parameters in patients with AIBD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study collected data on autoantibody titers and platelet-related parameters from 136 patients with bullous pemphigoid positive for anti-BP180 antibodies, 54 patients with pemphigus foliaceus positive for anti\u2013desmoglein (Dsg) 1 antibody, 55 patients with pemphigus vulgaris positive for both anti-Dsg1 and Dsg3 antibodies, and 16 patients with pemphigus vulgaris positive for anti-Dsg3 antibody alone. Two groups of healthy individuals served as controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Comparative analyses revealed clinically significantly elevated platelet-related parameters, such as platelet count and thrombocytocrit, in the autoantibody-positive patient groups relative to control individuals. Correlation analyses demonstrated statistically significant positive associations between autoantibody titers and specific platelet-related parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>These findings represent the first documented evidence of a positive correlation between autoantibody titers and platelet-related parameters in patients with AIBDs. The data implied that platelets may contribute to the disease pathophysiology and progression of AIBDs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/labmed\/lmaf094","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T12:56:14Z","timestamp":1766148974000},"source":"Crossref","is-referenced-by-count":0,"title":["Correlation of platelet-related parameters and autoantibodies in patients with autoimmune bullous diseases"],"prefix":"10.1093","volume":"57","author":[{"given":"Zhijun","family":"Zhou","sequence":"first","affiliation":[{"name":"Dermatology Hospital of Jiangxi Province, Jiangxi Provincial Clinical Research Center for Skin Diseases, Candidate Branch of the National Clinical Research Center for Skin Diseases, JXHC Key Laboratory of Skin Infection and Immunity, The Affiliated Dermatology Hospital of Nanchang University , Nanchang,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Qian","sequence":"additional","affiliation":[{"name":"Daqing Oilfield General Hospital Central Laboratory and Department of Dermatology, , Daqing,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huicheng","family":"Li","sequence":"additional","affiliation":[{"name":"Dermatology Hospital of Jiangxi Province, Jiangxi Provincial Clinical Research Center for Skin Diseases, Candidate Branch of the National Clinical Research Center for Skin Diseases, JXHC Key Laboratory of Skin Infection and Immunity, The Affiliated Dermatology Hospital of Nanchang University , Nanchang,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dantong","family":"Chen","sequence":"additional","affiliation":[{"name":"Daqing Longnan Hospital Department of Dermatology, , Daqing,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohua","family":"Tao","sequence":"additional","affiliation":[{"name":"Dermatology Hospital of Jiangxi Province, Jiangxi Provincial Clinical Research Center for Skin Diseases, Candidate Branch of the National Clinical Research Center for Skin Diseases, JXHC Key Laboratory of Skin Infection and Immunity, The Affiliated Dermatology Hospital of Nanchang University , Nanchang,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Jin","sequence":"additional","affiliation":[{"name":"Dermatology Hospital of Jiangxi Province, Jiangxi Provincial Clinical Research Center for Skin Diseases, Candidate Branch of the National Clinical Research Center for Skin Diseases, JXHC Key Laboratory of Skin Infection and Immunity, The Affiliated Dermatology Hospital of Nanchang University , Nanchang,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingxue","family":"Zhu","sequence":"additional","affiliation":[{"name":"College of Life and Health, Dalian University , Dalian,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoguang","family":"Li","sequence":"additional","affiliation":[{"name":"Daqing Oilfield General Hospital Central Laboratory and Department of Dermatology, , Daqing,","place":["China"]},{"name":"Department of Laboratory Medicine, Medical College, Dalian University , Dalian,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"2026030406391573100_lmaf094-B1","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1080\/1744666X.2025.2465405","article-title":"Diagnostic methods and strategies for autoimmune bullous 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