{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T11:24:18Z","timestamp":1762082658484,"version":"build-2065373602"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T00:00:00Z","timestamp":1670889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Victorian Medical Research Acceleration fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,23]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The AnyPlexTM II STI-7e panel assay (Seegene) detects seven sexually transmitted organisms (Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, M. hominis, Ureaplasma urealyticum, U. parvum, and Trichomonas vaginalis). This study compared the performance of AnyPlexTM II STI-7e with standard-of-care diagnostic methods. Samples (cervical or vaginal swabs, or urine) from 1330 women were tested on standard-of-care assays; 83\/1318 (6.3%) tested positive for M. genitalium (ResistancePlus\u00ae MG), 99\/1317 (7.5%) positive for C. trachomatis and 11\/1316 (0.8%) positive for N. gonorrhoeae (Hologic\u00ae Aptima Combo 2\u00ae), and 6\/689 (0.9%) positive for T. vaginalis (wet mount microscopy). AnyPlexTM II STI-7e had good agreement for the detection of M. genitalium [Cohen\u2019s kappa of 0.80, 95% confidence intervals (CI) 0.74\u20130.87] and C. trachomatis (kappa of 0.87, 95% CI 0.82\u20130.92), with positive and negative % agreement\u00a0&amp;gt;96% for both infections. There was lower agreement for the detection of N. gonorrhoeae (kappa of 0.37, 95%CI 0.19\u20130.55) and T. vaginalis (kappa of 0.521, 95%CI 0.25\u20130.80). In summary, the test performed well in this comparison for M. genitalium and C. trachomatis detection, but results were less conclusive for N. gonorrhoeae and T. vaginalis due to low prevalence in the population.<\/jats:p>","DOI":"10.1093\/lambio\/ovac002","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T13:42:25Z","timestamp":1712583745000},"source":"Crossref","is-referenced-by-count":3,"title":["Comparison of Seegene AnyPlexTM II STI-7e with standard-of-care diagnostic methods for the detection of <i>Mycoplasma genitalium, Chlamydia trachomatis, Neisseria gonorrhoeae<\/i>, and <i>Trichomonas vaginalis<\/i>"],"prefix":"10.1093","volume":"76","author":[{"given":"Kaveesha","family":"Bodiybadu","sequence":"first","affiliation":[{"name":"Centre for Women\u2019s Infectious Diseases, The Royal Women's Hospital , Parkville, VIC 3052 , Australia"},{"name":"Murdoch Children\u2019s Research Institute , Parkville, VIC 3052 , Australia"},{"name":"Department of Obstetrics and Gynaecology, University of Melbourne , Parkville, VIC 3010 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Danielewski","sequence":"additional","affiliation":[{"name":"Centre for Women\u2019s Infectious Diseases, The Royal Women's Hospital , Parkville, VIC 3052 , Australia"},{"name":"Murdoch Children\u2019s Research Institute , Parkville, VIC 3052 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5710-2671","authenticated-orcid":false,"given":"Erica","family":"Plummer","sequence":"additional","affiliation":[{"name":"Centre for Women\u2019s Infectious Diseases, The Royal Women's Hospital , Parkville, VIC 3052 , Australia"},{"name":"Murdoch Children\u2019s Research Institute , Parkville, VIC 3052 , Australia"},{"name":"Melbourne Sexual Health Centre, Alfred Health , Melbourne, VIC 3053 , Australia"},{"name":"Central Clinical School, Monash University , Melbourne, VIC 3800 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catriona S","family":"Bradshaw","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre, Alfred Health , Melbourne, VIC 3053 , Australia"},{"name":"Central Clinical School, Monash University , Melbourne, VIC 3800 , Australia"},{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne , Melbourne, VIC 3010 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorothy A","family":"Machalek","sequence":"additional","affiliation":[{"name":"Centre for Women\u2019s Infectious Diseases, The Royal Women's Hospital , Parkville, VIC 3052 , Australia"},{"name":"The Kirby Institute, University of New South Wales , Kensington, Sydney, NSW 2052 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne M","family":"Garland","sequence":"additional","affiliation":[{"name":"Centre for Women\u2019s Infectious Diseases, The Royal Women's Hospital , Parkville, VIC 3052 , Australia"},{"name":"Murdoch Children\u2019s Research Institute , Parkville, VIC 3052 , Australia"},{"name":"Department of Obstetrics and Gynaecology, University of Melbourne , Parkville, VIC 3010 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lenka A","family":"Vodstrcil","sequence":"additional","affiliation":[{"name":"Melbourne Sexual Health Centre, Alfred Health , Melbourne, VIC 3053 , Australia"},{"name":"Central Clinical School, Monash University , Melbourne, VIC 3800 , Australia"},{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne , Melbourne, VIC 3010 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald L","family":"Murray","sequence":"additional","affiliation":[{"name":"Centre for Women\u2019s Infectious Diseases, The Royal Women's Hospital , Parkville, 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