{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T21:29:51Z","timestamp":1792877391027,"version":"4.5.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The performance of lateral flow assay (LFA) in diagnosing invasive pulmonary aspergillosis (IPA) has not been well demonstrated. To address this, we conducted a meta-analysis assessing the overall accuracy of LFA in diagnosing IPA using bronchoalveolar lavage fluid (BALF). Over a systematical search and assessment of bias risk, we calculated the pooled specificity, sensitivity, and area under the receiver operating curve (AUC) to assess the diagnostic performance. Our meta-analysis included 11 studies. The combined total sensitivity and specificity for diagnosing IPA were 0.78 (95% confidence interval (CI): 0.71, 0.83) and 0.87 (95% CI: 0.81, 0.91), respectively. The AUC was 0.86 (95% CI: 0.82, 0.89). Our results demonstrate that LFA using galactomannan in BALF exhibits high sensitivity and specificity for diagnosing IPA.<\/jats:p>","DOI":"10.1093\/lambio\/ovad110","type":"journal-article","created":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T20:57:11Z","timestamp":1695848231000},"source":"Crossref","is-referenced-by-count":6,"title":["Diagnosis of invasive pulmonary aspergillosis by lateral flow assay of galactomannan in bronchoalveolar lavage fluid: a meta-analysis of diagnostic performance"],"prefix":"10.1093","volume":"76","author":[{"given":"Yingli","family":"Cai","sequence":"first","affiliation":[{"name":"Department of Emergency, The First People\u2019s Hospital of Zhaoqing , Zhaoqing 526000 , China"},{"name":"Jinan University , Guangzhou 510632 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Emergency, The First People\u2019s Hospital of Zhaoqing , Zhaoqing 526000 , China"},{"name":"Jinan University , Guangzhou 510632 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangsheng","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Emergency, The First People\u2019s Hospital of Zhaoqing , Zhaoqing 526000 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yankun","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Emergency, The First People\u2019s Hospital of Zhaoqing , Zhaoqing 526000 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwei","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Emergency, The First People\u2019s Hospital of Zhaoqing , Zhaoqing 526000 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhusheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Emergency, The First People\u2019s Hospital of Zhaoqing , Zhaoqing 526000 , 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