{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T10:24:45Z","timestamp":1769509485283,"version":"3.49.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T00:00:00Z","timestamp":1711497600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001691","name":"JSPS","doi-asserted-by":"publisher","award":["20K18927"],"award-info":[{"award-number":["20K18927"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Staphylococcus argenteus has received increased attention from an aspect of food safety since several food poisoning outbreaks caused by the bacterium were reported in Japan. However, S. argenteus prevalence among food handlers and utensils has not yet been investigated. In this study, we investigated S. argenteus prevalence among a collection of coagulase-positive staphylococci (CPS) that were isolated during food sanitary inspections in Japan. Out of a total of 191 CPS isolates, 14 were identified as S. argenteus. One was isolated from shelled shrimp, nine were isolated from food handlers\u2019 hand swabs, and four were isolated from kitchen utensils. Whole-genome sequencing revealed that transmission of S. argenteus from human hands to utensils was possible. Though all 14 isolates were negative for the pvl and tst-1 genes, 6 harbored the seb gene. Only 21.4% of S. argenteus isolates were resistant to antibiotics, while 62.1% of the S. aureus isolates from the same sources were confirmed to be resistant. To the best of our knowledge, this is the first report to demonstrate possible transmission of S. argenteus from food handlers to utensils in food-processing environments.<\/jats:p>","DOI":"10.1093\/lambio\/ovae031","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T05:29:47Z","timestamp":1711603787000},"source":"Crossref","is-referenced-by-count":4,"title":["Prevalence of <i>Staphylococcus argenteus<\/i> among food handlers, kitchen utensils, and food samples in Japan"],"prefix":"10.1093","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9786-9121","authenticated-orcid":false,"given":"Yuki","family":"Wakabayashi","sequence":"first","affiliation":[{"name":"Bacteriology Section, Division of Microbiology, Osaka Institute of Public Health , 1-3-3 Nakamichi, Higashinari-ku, Osaka, 537-0025 , Japan"},{"name":"Graduate School of Veterinary Science, Department of Veterinary Science, Osaka Metropolitan University , 1-58 Rinku Ourai Kita, Izumisano, Osaka, 598-0048 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Kumeda","sequence":"additional","affiliation":[{"name":"Research Center of Microorganism Control, Organization for Research Promotion, Osaka Metropolitan University , 1-1 Gakuen-cho, Naka-kyu, Sakai, Osaka, 599-8231 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shizue","family":"Yoshihara","sequence":"additional","affiliation":[{"name":"Graduate School of Science, Department of Biology, Osaka Metropolitan University , 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka, 599-8231 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayato","family":"Tokumoto","sequence":"additional","affiliation":[{"name":"Graduate School of Science, Department of Biology, Osaka Metropolitan University , 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka, 599-8231 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Kawatsu","sequence":"additional","affiliation":[{"name":"Bacteriology Section, Division of Microbiology, Osaka Institute of Public Health , 1-3-3 Nakamichi, Higashinari-ku, Osaka, 537-0025 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masami","family":"Miyake","sequence":"additional","affiliation":[{"name":"Graduate School of Veterinary Science, Department of Veterinary Science, Osaka Metropolitan University , 1-58 Rinku Ourai Kita, Izumisano, Osaka, 598-0048 , Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,3,27]]},"reference":[{"key":"2024041606121662000_bib1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3390\/toxins9080241","article-title":"Prevalence and genetic characteristics of Staphylococcus aureus and Staphylococcus argenteus isolates harboring Panton-Valentine leukocidin, enterotoxins, and TSST-1 genes from food handlers in Myanmar","volume":"9","author":"Aung","year":"2017","journal-title":"Toxins"},{"key":"2024041606121662000_bib2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1099\/jmm.0.000869","article-title":"Molecular characterization of Staphylococcus argenteus in Myanmar: identification of novel genotypes\/clusters in staphylocoagulase, protein a, alpha-haemolysin and other virulence factors","volume":"68","author":"Aung","year":"2019","journal-title":"J Med Microbiol"},{"key":"2024041606121662000_bib3","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3390\/pathogens10020163","article-title":"Distribution of virulence factors and resistance determinants in three genotypes of Staphylococcus argenteus clinical isolates in Japan","volume":"10","author":"Aung","year":"2021","journal-title":"Pathogens"},{"key":"2024041606121662000_bib4","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1007\/s10096-021-04204-7","article-title":"Methicillin-resistant Staphylococcus argenteus in the Netherlands: not a new arrival","volume":"40","author":"Bank","year":"2021","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"2024041606121662000_bib5","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.cmi.2019.02.028","article-title":"Implications of identifying the recently defined members of the Staphylococcus aureus complex S. argenteus and S. schweitzeri: a position paper of members of the ESCMID study group for Staphylococci and staphylococcal diseases (ESGS)","volume":"25","author":"Becker","year":"2019","journal-title":"Clin Microbiol Infect"},{"key":"2024041606121662000_bib6","doi-asserted-by":"crossref","first-page":"e32","DOI":"10.4081\/ijfs.2013.e32","article-title":"Enterotoxigenic strain of Staphylococcus aureus causing food-borne outbreak in a private context","volume":"2","author":"Bianchi","year":"2013","journal-title":"Ital J Food Safety"},{"key":"2024041606121662000_bib7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.jiph.2015.08.001","article-title":"Food handlers as potential sources of dissemination of virulent strains of Staphylococcus aureus in the community","volume":"9","author":"Castro","year":"2016","journal-title":"J Infect Public Health"},{"key":"2024041606121662000_bib8","doi-asserted-by":"crossref","first-page":"458.e11","DOI":"10.1016\/j.cmi.2016.01.008","article-title":"Comparison of community-onset Staphylococcus argenteus and Staphylococcus aureus sepsis in Thailand: a prospective multicenter observational study","volume":"22","author":"Chantratita","year":"2016","journal-title":"Clin Microbiol Infect"},{"key":"2024041606121662000_bib9","doi-asserted-by":"crossref","first-page":"i884","DOI":"10.1093\/bioinformatics\/bty560","article-title":"Fastp: an ultra-fast all-in-one FASTQ preprocessor","volume":"34","author":"Chen","year":"2018","journal-title":"Bioinformatics"},{"key":"2024041606121662000_bib10","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.ijantimicag.2018.08.017","article-title":"High mortality impact of Staphylococcus argenteus on patients with community-onset staphylococcal bacteraemia","volume":"52","author":"Chen","year":"2018","journal-title":"Int J Antimicrob Agents"},{"key":"2024041606121662000_bib11","doi-asserted-by":"crossref","first-page":"005067","DOI":"10.1099\/ijsem.0.005067","article-title":"Staphylococcus singaporensis sp. nov., a new member of the Staphylococcus aureus complex, isolated from human clinical specimens","volume":"71","author":"Chew","year":"2021","journal-title":"Int J Syst Evol Microbiol"},{"key":"2024041606121662000_bib12","doi-asserted-by":"crossref","first-page":"e328","DOI":"10.1016\/S2666-5247(20)30149-X","article-title":"Definition of a genetic relatedness cutoff to exclude recent transmission of methicillin-resistant Staphylococcus aureus: a genomic epidemiology analysis","volume":"1","author":"Coll","year":"2020","journal-title":"Lancet Microbe"},{"key":"2024041606121662000_bib13","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1089\/fpd.2004.1.241","article-title":"A case study of a massive staphylococcal food poisoning incident","volume":"1","author":"Do\u00a0Carmo","year":"2004","journal-title":"Foodborne Pathog Dis"},{"key":"2024041606121662000_bib14","doi-asserted-by":"crossref","first-page":"e02470","DOI":"10.1128\/JCM.02470-20","article-title":"Phenotypic and genomic profiling of Staphylococcus argenteus in Canada and the United States and recommendations for clinical result reporting","volume":"59","author":"Eshaghi","year":"2021","journal-title":"J Clin Microbiol"},{"key":"2024041606121662000_bib15","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1186\/1471-2105-10-152","article-title":"Global optimal eBURST analysis of multilocus typing data using a graphic matroid approach","volume":"10","author":"Francisco","year":"2009","journal-title":"BMC Bioinf"},{"key":"2024041606121662000_bib16","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1111\/j.1574-6976.2011.00311.x","article-title":"Staphylococcus aureus and its food poisoning toxins: characterization and outbreak investigation","volume":"36","author":"Hennekinne","year":"2012","journal-title":"FEMS Microbiol Rev"},{"key":"2024041606121662000_bib17","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.3390\/antibiotics10111316","article-title":"Antimicrobial resistance and molecular epidemiological characteristics of methicillin-resistant and susceptible staphylococcal isolates from oral cavity of dental patients and staff in Northern Japan","volume":"10","author":"Hirose","year":"2021","journal-title":"Antibiotics"},{"key":"2024041606121662000_bib18","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.ajic.2015.03.022","article-title":"Tracking sources of Staphylococcus aureus hand contamination in food handlers by spa typing","volume":"43","author":"Ho","year":"2015","journal-title":"Am J Infect Control"},{"key":"2024041606121662000_bib19","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jinf.2021.08.040","article-title":"Staphylococcus argenteus transmission among healthy Royal Marines: a molecular epidemiology case-study","volume":"83","author":"Jauneikaite","year":"2021","journal-title":"J Infect"},{"key":"2024041606121662000_bib20","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.4315\/0362-028X-67.6.1116","article-title":"Ribotyping and a study of transmission of Staphylococcus aureus collected from food preparation facilities","volume":"67","author":"Kishimoto","year":"2004","journal-title":"J Food Prot"},{"key":"2024041606121662000_bib21","doi-asserted-by":"crossref","first-page":"W293","DOI":"10.1093\/nar\/gkab301","article-title":"Interactive tree of life (iTOL) v5: an online tool for phylogenetic tree display and annotation","volume":"49","author":"Letunic","year":"2021","journal-title":"Nucleic Acids Res"},{"key":"2024041606121662000_bib22","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1128\/JCM.00836-06","article-title":"Use of single-nucleotide polymorphism genotyping system to demonstrate the unique epidemiology of methicillin-resistant Staphylococcus aureus in remote Aboriginal communities","volume":"44","author":"McDonald","year":"2006","journal-title":"J Clin Microbiol"},{"key":"2024041606121662000_bib23","doi-asserted-by":"crossref","first-page":"3334","DOI":"10.1128\/JCM.00880-06","article-title":"Staphylococcus aureus throat colonization is more frequent than colonization in the anterior nares","volume":"44","author":"Nilsson","year":"2006","journal-title":"J Clin Microbiol"},{"key":"2024041606121662000_bib24","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1093\/molbev\/msp077","article-title":"FastTree: computing large minimum evolution trees with profiles instead of a distance matrix","volume":"26","author":"Price","year":"2009","journal-title":"Mol Biol Evol"},{"key":"2024041606121662000_bib25","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.3201\/eid2410.180727","article-title":"Community-acquired Staphylococcus argenteus sequence type 2250 bone and joint infection, France, 2017","volume":"24","author":"Rigaill","year":"2018","journal-title":"Emerg Infect Dis"},{"key":"2024041606121662000_bib26","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1086\/655901","article-title":"Are host genetics the predominant determinant of persistent nasal Staphylococcus aureus carriage in humans?","volume":"202","author":"Ruimy","year":"2010","journal-title":"J Infect Dis"},{"key":"2024041606121662000_bib27","doi-asserted-by":"crossref","first-page":"5577","DOI":"10.1128\/JB.00493-09","article-title":"Comparisons between geographically diverse samples of carried Staphylococcus aureus","volume":"191","author":"Ruimy","year":"2009","journal-title":"J Bacteriol"},{"key":"2024041606121662000_bib28","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ijmm.2016.11.003","article-title":"Differentiation of Staphylococcus argenteus (formerly: s taphylococcus aureus clonal complex 75) by mass spectrometry from S. aureus using the first strain isolated from a wild African great ape","volume":"307","author":"Schuster","year":"2017","journal-title":"Int J Med Microbiol"},{"key":"2024041606121662000_bib29","doi-asserted-by":"crossref","DOI":"10.1099\/ijsem.0.004996","article-title":"Characterization of Staphylococcus roterodami sp. nov., a new species within the Staphylococcus aureus complex isolated from a human foot infection","volume":"71","author":"Schutte","year":"2021","journal-title":"Int J Syst Evol Microbiol"},{"key":"2024041606121662000_bib30","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ijfoodmicro.2017.09.005","article-title":"Food poisoning outbreak in Tokyo, Japan caused by Staphylococcus argenteus","volume":"262","author":"Suzuki","year":"2017","journal-title":"Int J Food Microbiol"},{"key":"2024041606121662000_bib31","doi-asserted-by":"crossref","first-page":"20","DOI":"10.5803\/jsfm.37.20","article-title":"Identification and characterization of Staphylococcus argenteus isolates in food poisoning case in Akita Prefecture","volume":"37","author":"Takahashi","year":"2020","journal-title":"Jpn J Food Microbiol"},{"key":"2024041606121662000_bib32","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.4315\/0362-028X-71.12.2582","article-title":"Outbreaks where food workers have been implicated in the spread of foodborne disease part 5. Sources of contamination and pathogen excretion from infected persons","volume":"71","author":"Todd","year":"2008","journal-title":"J Food Prot"},{"key":"2024041606121662000_bib33","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1099\/ijs.0.062752-0","article-title":"Novel staphylococcal species that form part of a Staphylococcus aureus-related complex: the non-pigmented Staphylococcus argenteus sp. nov. and the non-human primate-associated Staphylococcus schweitzeri sp. nov","volume":"65","author":"Tong","year":"2015","journal-title":"Int J Syst Evol Microbiol"},{"key":"2024041606121662000_bib34","doi-asserted-by":"crossref","first-page":"93","DOI":"10.12688\/wellcomeopenres.14694.1","article-title":"RhierBAPS: an R implementation of the population clustering algorithm hierBAPS. Version 1","volume":"3","author":"Tonkin-Hill","year":"2018","journal-title":"Wellcome Open Res"},{"key":"2024041606121662000_bib35","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3390\/antibiotics8030097","article-title":"Comparison of antibiotic resistance profile and biofilm production of Staphylococcus aureus isolates derived from human specimens and animal-derived samples","volume":"8","author":"Vitale","year":"2019","journal-title":"Antibiotics"},{"key":"2024041606121662000_bib36","doi-asserted-by":"crossref","first-page":"109503","DOI":"10.1016\/j.ijfoodmicro.2021.109503","article-title":"Isolation and characterization of Staphylococcus argenteus strains from retail foods and slaughterhouses in Japan","volume":"363","author":"Wakabayashi","year":"2022","journal-title":"Int J Food Microbiol"},{"key":"2024041606121662000_bib37","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ijfoodmicro.2017.10.022","article-title":"Staphylococcal food poisoning caused by Staphylococcus argenteus harboring staphylococcal enterotoxin genes","volume":"265","author":"Wakabayashi","year":"2018","journal-title":"Int J Food Microbiol"},{"key":"2024041606121662000_bib38","first-page":"e000261","article-title":"Evaluation of SNP calling methods for closely related bacterial isolates and a novel high-accuracy pipeline: bactSNP","volume":"5","author":"Yoshimura","year":"2019","journal-title":"Microb Genom"}],"container-title":["Letters in Applied Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/lambio\/advance-article-pdf\/doi\/10.1093\/lambio\/ovae031\/57105833\/ovae031.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/lambio\/article-pdf\/77\/4\/ovae031\/57239110\/ovae031.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/lambio\/article-pdf\/77\/4\/ovae031\/57239110\/ovae031.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T06:12:45Z","timestamp":1713247965000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/lambio\/article\/doi\/10.1093\/lambio\/ovae031\/7636492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,27]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4,8]]}},"URL":"https:\/\/doi.org\/10.1093\/lambio\/ovae031","relation":{},"ISSN":["1472-765X"],"issn-type":[{"value":"1472-765X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,4]]},"published":{"date-parts":[[2024,3,27]]},"article-number":"ovae031"}}