{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:08:13Z","timestamp":1753877293507,"version":"3.41.2"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100009122","name":"Ministry of Higher Education and Scientific Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009122","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005307","name":"DGRSDT","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005307","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The objective of this study was to characterize Staphylococcus aureus isolates recovered from the nasal samples of healthy pet cats in Algiers province. A total of 138 nasal swabs were collected. Antimicrobial susceptibility was conducted using the disk-diffusion method and the VITEK-2 susceptibility system. Whole genome sequencing was performed to identify multiple-locus sequence typing, antimicrobial and virulence genes. Staphylococcus aureus isolates were detected in 23 cats. Among these, 11 were methicillin-resistant S. aureus (MRSA) (one isolate\/sample). Three sequence types (ST6, ST5, and ST1) were identified in MRSA, with the predominance of ST6 (n\u00a0=\u00a07). Seven distinct STs [ST398, ST97, ST15, ST7, ST291, ST5043, and a new ST, (ST9219)] were detected in methicillin-sensitive S. aureus. All MRSA isolates harbored the mecA gene and SCCmec-type-IVa. MRSA exhibited resistance to tetracycline [n\u00a0=\u00a03\/tet(L) and tet(M); n\u00a0=\u00a01\/tet(K)], kanamycin-tobramycin [n\u00a0=\u00a03\/ant(4\u2032)-Ia), amikacin-kanamycin (n\u00a0=\u00a01\/aph(3\u2032)-IIIa], and erythromycin-clindamycin [n\u00a0=\u00a01\/erm(C)]. Seven S. aureus isolates were multidrug resistant. All the isolates were negative for lukS\/lukF-PV and tst-1 genes, while 20 isolates were IEC-positive. This study revealed a diversity of genetic lineages in S. aureus strains isolated from nasal samples of pet cats, including multidrug-resistant and toxigenic strains. The presence of IEC-positive S. aureus suggests possible human\u2013animal transmission.<\/jats:p>","DOI":"10.1093\/lambio\/ovae108","type":"journal-article","created":{"date-parts":[[2024,11,10]],"date-time":"2024-11-10T04:33:04Z","timestamp":1731213184000},"source":"Crossref","is-referenced-by-count":1,"title":["Molecular characterization of <i>Staphylococcus aureus<\/i> from nasal samples of healthy pet cats"],"prefix":"10.1093","volume":"77","author":[{"given":"Amel","family":"Bezzi","sequence":"first","affiliation":[{"name":"Microbiology Group, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Science and Technology\u2014Houari Boumediene , 16111 Bab Ezzouar, Algiers ,","place":["Algeria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3872-1842","authenticated-orcid":false,"given":"Kenza","family":"Antri","sequence":"additional","affiliation":[{"name":"Microbiology Group, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Science and Technology\u2014Houari Boumediene , 16111 Bab Ezzouar, Algiers ,","place":["Algeria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed Azzedine","family":"Bachtarzi","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Mustapha Bacha, Service de Microbiologie , 16000 Alger ,","place":["Alg\u00e9rie"]},{"name":"Faculty of Pharmacy, University of Algiers Ben Youssef Ben Khadda , 16000 Algiers ,","place":["Algeria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5130-6016","authenticated-orcid":false,"given":"Patricia","family":"Martins-Simoes","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Centre National de R\u00e9f\u00e9rence des Staphylocoques, Institut des Agents Infectieux , LyonF-69004 ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6282-6498","authenticated-orcid":false,"given":"Benjamin","family":"Youenou","sequence":"additional","affiliation":[{"name":"Hospices Civils de Lyon, Centre National de R\u00e9f\u00e9rence des Staphylocoques, Institut des Agents Infectieux , LyonF-69004 ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Gourari","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire Mustapha Bacha, Service de Microbiologie , 16000 Alger ,","place":["Alg\u00e9rie"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farida","family":"Nateche","sequence":"additional","affiliation":[{"name":"Microbiology Group, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Science and Technology\u2014Houari Boumediene , 16111 Bab Ezzouar, Algiers 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