{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T08:28:57Z","timestamp":1766996937177,"version":"3.48.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Bacterial carotenoids are of significant industrial interest due to their bioactive properties. This study aimed to isolate carotenoid-producing bacteria from Egyptian agricultural land and screen key parameters to enhance their pigment yield. The most productive isolatesse were identified as Exiguobacterium acetylicum and Arthrobacter gandavensis. A one-variable-at-a-time approach revealed that maximum carotenoid production was highly strain-specific. Following cell disruption via mild acid hydrolysis, the optimal extraction solvents were pure acetone for A. gandavensis (4.74\u00a0mg L\u22121) and a 1:1 acetone:methanol mixture for E. acetylicum (5.87\u00a0mg L\u22121). While both strains achieved peak carotenoid production in nutrient broth at 48 hours and pH 6.0, their optimal growth temperatures diverged; A. gandavensis thrived at 35\u00b0C and E. acetylicum at 25\u00b0C. Liquid chromatography mass spectrometery analysis of A. gandavensis revealed a carotenoid profile containing zeaxanthin, decaprenoxanthin, bacterioruberin, and arthroxanthin. The extract exhibited mechanism-dependent antioxidant activity, most notably a robust peroxyl radical scavenging capacity (421.13\u00a0\u00b5M TE\/mg in ORAC). These findings underscore the necessity of strain-specific screening to maximize the potential of bacterial sources for producing natural carotenoids with distinct antioxidant profiles.<\/jats:p>","DOI":"10.1093\/lambio\/ovaf142","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T12:54:29Z","timestamp":1766148869000},"source":"Crossref","is-referenced-by-count":0,"title":["Characterization of carotenoid production and antioxidant capacity in an Egyptian soil bacterium"],"prefix":"10.1093","volume":"78","author":[{"given":"Nora","family":"Elfeky","sequence":"first","affiliation":[{"name":"Anhui Provincial Key Laboratory of Molecular Enzymology and Mechanism of Major Metabolic Diseases, College of Life Sciences, Anhui Normal University , Wuhu 241000, Anhui ,","place":["China"]},{"name":"Menoufia University Botany and Microbiology Department, Faculty of Science, , Shibin Elkom 32511 ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Souzan Hassen A","family":"Helal","sequence":"additional","affiliation":[{"name":"Menoufia University Botany and Microbiology Department, Faculty of Science, , Shibin Elkom 32511 ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdallah A S","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Menoufia University Chemistry Department, Faculty of Science, , Shebin El-Kom 32511 ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabha M","family":"El-Sabbagh","sequence":"additional","affiliation":[{"name":"Menoufia University Botany and Microbiology Department, Faculty of Science, , Shibin Elkom 32511 ,","place":["Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"2025122903264910800_bib1","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.1006082","article-title":"Carotenoids and their Antioxidant Power, in: The Power of Antioxidants - Unleashing Nature\u2019s Defense against Oxidative Stress","author":"Arslansoy","year":"2024","journal-title":"Biochemistry"},{"key":"2025122903264910800_bib2","first-page":"29","article-title":"DPPH free radical scavenging activity of two extracts from Agelanthus dodoneifolius (Loranthaceae) leaves","volume":"8","author":"Boly","year":"2016","journal-title":"Int J Toxicol Pharmacol Res"},{"key":"2025122903264910800_bib4","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1111\/ijfs.13879","article-title":"Carotenoid profile produced by Bacillus licheniformis Rt4M10 Isolated from grapevines grown in high altitude and their antioxidant activity","volume":"53","author":"Cohen","year":"2018","journal-title":"Int J Food Sci Technol"},{"key":"2025122903264910800_bib5","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1016\/j.sjbs.2019.11.031","article-title":"Characterization and antifungal activity of the yellow pigment produced by a Bacillus sp. 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