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We conducted a comprehensive Bayesian analysis to assess the impact of LIT on RSA. Using data from the Shenzhen Maternity and Child Healthcare Hospital (2001\u20132020, n\u2005=\u20052316), a Bayesian generalized linear model with predictive projection feature selection was employed. Our analysis revealed a significant improvement in live birth rates for RSA patients undergoing LIT. Notably, LIT had a greater impact compared to the other 85 factors considered. To mitigate research bias, we conducted a Bayesian meta-analysis combining our dataset with 19 previously reported studies (1985\u20132021, n\u2005=\u20054246). Additionally, we developed an empirical model highlighting the four key factors, which are the LIT result, age, paternal blood type, and anticardiolipin antibody. Younger age (19\u201327), paternal blood type B, and a positive anticardiolipin antibody (IgM) were associated with better therapeutic outcomes in LIT for RSA. These findings aid clinicians in identifying suitable candidates for LIT and improving treatment outcomes.<\/jats:p>","DOI":"10.1093\/lifemedi\/lnad049","type":"journal-article","created":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T03:00:23Z","timestamp":1702090823000},"source":"Crossref","is-referenced-by-count":0,"title":["A comprehensive Bayesian analysis assessing the effectiveness of lymphocyte immunotherapy for recurrent spontaneous abortion"],"prefix":"10.1093","volume":"2","author":[{"given":"Rongzhou","family":"Chen","sequence":"first","affiliation":[{"name":"Tsinghua Shenzhen International Graduate, Tsinghua University , Shenzhen 518055 , China"},{"name":"Tsinghua-Berkeley Shenzhen Institute , Shenzhen 518055 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haohan","family":"Xu","sequence":"additional","affiliation":[{"name":"Tsinghua Shenzhen International Graduate, Tsinghua University , Shenzhen 518055 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yujia","family":"Hou","sequence":"additional","affiliation":[{"name":"Tsinghua Shenzhen International Graduate, Tsinghua University , Shenzhen 518055 , China"},{"name":"Tsinghua-Berkeley Shenzhen Institute , Shenzhen 518055 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanghang","family":"Liu","sequence":"additional","affiliation":[{"name":"Tsinghua Shenzhen International Graduate, Tsinghua University , Shenzhen 518055 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng","family":"Zheng","sequence":"additional","affiliation":[{"name":"Shenzhen Maternity and Child Healthcare Hospital , Shenzhen 518028 , China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4995-2032","authenticated-orcid":false,"given":"Shaohua","family":"Ma","sequence":"additional","affiliation":[{"name":"Tsinghua Shenzhen International Graduate, 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