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On 16 May 2025, the Aging Biomarker Consortium convened an expert consensus meeting in Shanghai, proposing a multidimensional biomarker framework: functional (estimated glomerular filtration rate, renal blood flow), structural (renal volume loss), and humoral (Klotho, N-terminal Pro-B-type natriuretic peptide, senescence-associated secretory phenotype factors). The consensus also supports machine-learning models for biological age assessment and calls for multi-center cohorts and translational collaboration to improve elderly kidney health.<\/jats:p>","DOI":"10.1093\/lifemedi\/lnag026","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T11:50:57Z","timestamp":1783684257000},"source":"Crossref","is-referenced-by-count":1,"title":["A framework of biomarkers for renal aging: a consensus statement by the Aging Biomarker Consortium"],"prefix":"10.1093","volume":"5","author":[{"family":"Aging Biomarker Consortium","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4060-2423","authenticated-orcid":false,"given":"Xiaoyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Kidney Health Institute, East China Normal University , Shanghai 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