{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:17:13Z","timestamp":1792142233584,"version":"4.4.0"},"reference-count":176,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T00:00:00Z","timestamp":1686009600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Efficient communication between the brain and peripheral organs is indispensable for regulating physiological function and maintaining energy homeostasis. The peripheral nervous system (PNS) in vertebrates, consisting of the autonomic and somatic nervous systems, bridges the peripheral organs and the central nervous system (CNS). Metabolic signals are processed by both vagal sensory nerves and somatosensory nerves. The CNS receives sensory inputs via ascending nerves, serves as the coordination and integration center, and subsequently controls internal organs and glands via descending nerves. The autonomic nervous system consists of sympathetic and parasympathetic branches that project peripheral nerves into various anatomical locations to regulate the energy balance. Sympathetic and parasympathetic nerves typically control the reflexive and involuntary functions in organs. In this review article, we outline the innervation of adipose tissue, gut, pancreas, and liver, to illustrate the neurobiological basis of central\u2013peripheral interactions. We emphasize the importance of understanding the functional atlas of neural control of energy metabolism, and more importantly, provide potential avenues for further research in this area.<\/jats:p>","DOI":"10.1093\/lifemeta\/load022","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T09:50:37Z","timestamp":1686304237000},"source":"Crossref","is-referenced-by-count":30,"title":["Neural innervation in adipose tissue, gut, pancreas, and liver"],"prefix":"10.1093","volume":"2","author":[{"given":"Mengxue","family":"Sun","sequence":"first","affiliation":[{"name":"Institute for Immunology and School of Medicine, Tsinghua University, and Tsinghua-Peking Center for Life Sciences , Beijing 100084 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongwen","family":"Wan","sequence":"additional","affiliation":[{"name":"Institute for Immunology and School of Medicine, Tsinghua University, and Tsinghua-Peking Center for Life Sciences , Beijing 100084 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjie","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Pathology and Pathophysiology and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou, Zhejiang 310058 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuo-Xian","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Pathology and Pathophysiology and Department of Cardiology of the Second Affiliated Hospital, Zhejiang University School of Medicine , Hangzhou, Zhejiang 310058 , China"},{"name":"Key Laboratory of Disease Proteomics of Zhejiang Province, Zhejiang University School of Medicine , Hangzhou, Zhejiang 310058 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8544-3318","authenticated-orcid":false,"given":"Wenwen","family":"Zeng","sequence":"additional","affiliation":[{"name":"Institute for Immunology and School of Medicine, Tsinghua University, and Tsinghua-Peking Center for Life Sciences , Beijing 100084 , China"},{"name":"Beijing Key Laboratory for Immunological Research on Chronic Diseases , Beijing 100084 , China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,6,6]]},"reference":[{"key":"2023062503544649700_CIT0001","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1007\/s11427-021-2103-5","article-title":"Interactions between central nervous system and peripheral metabolic organs","volume":"65","author":"Zeng","year":"2022","journal-title":"Sci China Life 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