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This study characterized mesenchymal-like cells in quail embryo cartilage using histochemical staining, immunohistochemistry, and transmission electron microscopy (TEM). A unique population of cartilage-resident progenitor-like cells with flattened, migratory morphologies was identified. These cells co-expressed stemness markers (CD117, CD34), vascularization (VEGF), remodeling (MMP-9), phagocytosis (CD68), and the chondrogenic marker type II collagen. TEM revealed abundant rough endoplasmic reticulum and lysosomes, confirming active metabolic states. Quantitative analysis showed significant differences in marker expression, with CD34 showing the highest expression (p &amp;lt; 0.05). While these findings demonstrate a multifunctional profile, the study remains primarily descriptive and observational. 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