{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:48:25Z","timestamp":1740170905183,"version":"3.37.3"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"7-8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Factor VII (FVII) deficiency is a hereditary bleeding disorder that significantly increases the risk of hemorrhage during the intrapartum and postpartum periods as well as during surgery. Management often requires careful pre- and post-operative planning, a multi-disciplinary approach, and management at a tertiary center. Most cases in the literature utilized recombinant FVII for treatment. We present a case of a young active duty female who had an undiagnosed FVII deficiency that became apparent during her expedited delivery for fetal distress. Our patient was admitted for delivery while undergoing a work up for an abnormal coagulation panel. Given high suspicion for FVII deficiency, anticipated hemorrhage, and need for cesarean delivery, she was treated with blood products containing FVII. Two days after delivery her diagnosis was confirmed. Available literature discusses the management of known FVII deficiency in pregnancy; however, to the best of our knowledge, there are no cases of an unknown bleeding diathesis incidentally identified just before delivery and later diagnosed as FVII deficiency. This case highlights the appropriate management of an unknown coagulopathy, the significant challenges associated, and the incorporation of a multi-disciplinary team critical to reducing significant maternal morbidity.<\/jats:p>","DOI":"10.1093\/milmed\/usab169","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T22:16:36Z","timestamp":1619129796000},"page":"829-831","source":"Crossref","is-referenced-by-count":1,"title":["Preventing Surgical and Postpartum Hemorrhage in an Active Duty Patient With an Undiagnosed Coagulopathy at a Military Treatment Facility"],"prefix":"10.1093","volume":"186","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4657-2250","authenticated-orcid":false,"given":"Zachary A","family":"Kopelman","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Brooke Army Medical Center, Fort Sam Houston, TX 78234, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Villazana-Kretzer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Carl R. Darnall Army Medical Center, Fort Hood, TX 76544, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meghan","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Carl R. Darnall Army Medical Center, Fort Hood, TX 76544, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,7,1]]},"reference":[{"issue":"4","key":"2021070814062156600_R1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.5468\/ogs.2014.57.4.314","article-title":"Successful management of maternal factor VII deficiency in a cesarean section","volume":"57","author":"Lee","year":"2014","journal-title":"Obstet Gynecol Sci"},{"issue":"2","key":"2021070814062156600_R2","first-page":"136","article-title":"Factor VII deficiency and pregnancy: a case report and review of literature","volume":"60","author":"Zaidi","year":"2010","journal-title":"J Pak Med Assoc"},{"issue":"5","key":"2021070814062156600_R3","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.transci.2019.08.006","article-title":"An overview of inherited factor VII deficiency","volume":"58","author":"Robinson","year":"2019","journal-title":"Transfus Apher Sci"},{"issue":"7","key":"2021070814062156600_R4","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1177\/1076029616670257","article-title":"Factor VII deficiency: from basics to clinical laboratory diagnosis and patient management","volume":"23","author":"Sevenet","year":"2017","journal-title":"Clin Appl Thromb Hemost"},{"issue":"5","key":"2021070814062156600_R5","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1542\/peds.2012-3662","article-title":"Rare bleeding disorders in children: identification and primary care management","volume":"132","author":"Acharya","year":"2013","journal-title":"Pediatrics"},{"issue":"4","key":"2021070814062156600_R6","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/hae.14086","article-title":"Management of pregnancy in women with factor VII deficiency: a case series","volume":"26","author":"Lee","year":"2020","journal-title":"Haemophilia"},{"volume-title":"Fresh Frozen Plasma (FFP)","year":"2020","author":"Khawar","key":"2021070814062156600_R7"},{"issue":"6","key":"2021070814062156600_R8","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1093\/bja\/aeu158","article-title":"Cryoprecipitate therapy","volume":"113","author":"Nascimento","year":"2014","journal-title":"Br J Anaesth"},{"issue":"6","key":"2021070814062156600_R9","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1111\/j.1365-2516.2008.01844.x","article-title":"Factor VII deficiency: defining the clinical picture and optimizing therapeutic options","volume":"14","author":"Lapecorella","year":"2008","journal-title":"Haemophilia"},{"issue":"2","key":"2021070814062156600_R10","doi-asserted-by":"crossref","DOI":"10.1016\/j.hoc.2011.01.007","article-title":"Factor deficiencies in pregnancy","volume":"25","author":"Pike","year":"2011","journal-title":"Hematol Oncol Clin North Am"},{"article-title":"Army strategic and operational readiness","volume-title":"Army Regulation 525-30","author":"Department of the Army","key":"2021070814062156600_R11"},{"author":"A Day at the MEPS","key":"2021070814062156600_R12","article-title":"United States Military Entrance Processing Command website"}],"container-title":["Military Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/milmed\/article-pdf\/186\/7-8\/829\/38846253\/usab169.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/milmed\/article-pdf\/186\/7-8\/829\/38846253\/usab169.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T22:41:03Z","timestamp":1625784063000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/milmed\/article\/186\/7-8\/829\/6245905"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,1]]},"references-count":12,"journal-issue":{"issue":"7-8","published-online":{"date-parts":[[2021,7,1]]},"published-print":{"date-parts":[[2021,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/milmed\/usab169","relation":{},"ISSN":["0026-4075","1930-613X"],"issn-type":[{"type":"print","value":"0026-4075"},{"type":"electronic","value":"1930-613X"}],"subject":[],"published-other":{"date-parts":[[2021,7,1]]},"published":{"date-parts":[[2021,7,1]]}}}