{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:25:50Z","timestamp":1791379550163,"version":"4.3.3"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"3-4","license":[{"start":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T00:00:00Z","timestamp":1645920000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,20]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Graves\u2019 disease (GD) is the most common cause of hyperthyroidism in the clinic, accounting for about 85% of all hyperthyroidisms. However, hyperthyroidism combined with OH has been rarely reported in the international community. We analyzed the clinical characteristics and pathogenesis of GD combined with orthostatic hypotension. We conducted a retrospective analysis of 2 GD combined with orthostatic hypotension cases diagnosed by Chinese and Western Medical Association Hospital of Southern Medical University from July to August 2018 and discussed their clinical characteristics, treatment methods, and pathogenesis. The main clinical manifestations of both two patients with hyperthyroidism were vertigo during postural changes or activities and relief from supine position and blood volume supplementation. Considering the lack of blood volume, the symptoms were alleviated after symptomatic treatment. The possibility of hyperthyroidism combined with orthostatic hypotension should be taken into consideration in clinical diagnosis and treatment.<\/jats:p>","DOI":"10.1093\/milmed\/usac031","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T10:59:45Z","timestamp":1646132385000},"page":"841-843","source":"Crossref","is-referenced-by-count":2,"title":["Graves\u2019 Disease Combined With Orthostatic Hypotension: A Two-Case Report"],"prefix":"10.1093","volume":"188","author":[{"given":"Ya-Juan","family":"Han","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Metabolism, Guangzhou Eighth People\u2019s Hospital, Guangzhou Medical University , Guangzhou 510060, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao-Ying","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Guangzhou Eighth People\u2019s Hospital, Guangzhou Medical University , Guangzhou 510060, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Run","family":"Miao","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, TCM-Integrated Cancer Center of Southern Medical University , Guangzhou 510315, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, TCM-Integrated Cancer Center of Southern Medical University , Guangzhou 510315, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6936-2515","authenticated-orcid":false,"given":"Yu-Bing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Guangzhou Eighth People\u2019s Hospital, Guangzhou Medical University , Guangzhou 510060, PR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,2,27]]},"reference":[{"key":"2023033100484451900_","volume-title":"Pathology: Implications for the Physical Therapist","author":"Goodman","year":"2009"},{"issue":"9","key":"2023033100484451900_","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1007\/s00415-012-6736-7","article-title":"Neurogenic orthostatic hypotension: pathophysiology, evaluation, and management","volume":"260","author":"Metzler","year":"2013","journal-title":"J Neurol"},{"key":"2023033100484451900_","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-222355.","article-title":"More, less or both?","volume":"2018","author":"Attaye","year":"2018"},{"issue":"10","key":"2023033100484451900_","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1093\/ajh\/hpv022","article-title":"Orthostatic changes in blood pressure and mortality in the elderly: the Pro.V.A study","volume":"28","author":"Veronese","year":"2015","journal-title":"Am J Hypertens"},{"issue":"7","key":"2023033100484451900_","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1210\/jc.2003-032143","article-title":"Thyroid function and blood pressure homeostasis in euthyroid subjects","volume":"89","author":"Gumieniak","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"issue":"4595","key":"2023033100484451900_","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1136\/bmj.1.4595.169","article-title":"Alternating orthostatic hypotension and hyperthyroidism of probable hypophysial-hypoyhamic origin","volume":"1","author":"Diaz","year":"1949","journal-title":"Br Med J"},{"issue":"13 Suppl","key":"2023033100484451900_","first-page":"s258","article-title":"Managed care approach to the treatment of neurogenic orthostatic hypotension","volume":"21","author":"Isaacson","year":"2015","journal-title":"Am J Manag Care"}],"container-title":["Military Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/milmed\/article-pdf\/188\/3-4\/841\/49703716\/usac031.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/milmed\/article-pdf\/188\/3-4\/841\/49703716\/usac031.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T07:22:32Z","timestamp":1700292152000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/milmed\/article\/188\/3-4\/841\/6540065"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,27]]},"references-count":7,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2022,2,27]]},"published-print":{"date-parts":[[2023,3,20]]}},"URL":"https:\/\/doi.org\/10.1093\/milmed\/usac031","relation":{},"ISSN":["0026-4075","1930-613X"],"issn-type":[{"value":"0026-4075","type":"print"},{"value":"1930-613X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,3,1]]},"published":{"date-parts":[[2022,2,27]]}}}