{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T11:32:30Z","timestamp":1791977550220,"version":"4.4.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,23]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Vitamin toxicity represents an increasingly frequent clinical diagnosis and can be difficult to initially recognize given the plethora of over-the-counter supplements available. The young, active, and heavily male population of the military is especially susceptible to such supplementation pitfalls. Here we present the case of acute renal failure with hypercalcemia that was found to be secondary to unrecognized high-dose over-the-counter vitamin supplementation and subsequent vitamin D hypervitaminosis initiated by the patient in the hope of boosting testosterone production. This clinical scenario demonstrates the dangers of easily accessible, often seemingly benign supplements and the need for greater education and awareness of supplementation use.<\/jats:p>","DOI":"10.1093\/milmed\/usad237","type":"journal-article","created":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T03:06:56Z","timestamp":1688526416000},"page":"e417-e419","source":"Crossref","is-referenced-by-count":3,"title":["Vitamin D Abuse in\u00a0Pursuit of\u00a0\u201cGains\u201d Resulting in\u00a0Acute Kidney Injury"],"prefix":"10.1093","volume":"189","author":[{"given":"Nicholas","family":"Mason","sequence":"first","affiliation":[{"name":"Arizona College of Medicine, Midwestern University, Ocotillo Hall , Glendale, AZ 85308, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7148-2399","authenticated-orcid":false,"given":"Lauren M","family":"Sweet","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brooke Army Medical Center , San Antonio, TX 78219, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary","family":"Wills","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brooke Army Medical Center , San Antonio, TX 78219, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Schall","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Brooke Army Medical Center , San Antonio, TX 78219, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,7,4]]},"reference":[{"issue":"6","key":"2024012918213550200_R1","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1111\/bcp.13573","article-title":"A review of\u00a0the growing risk of\u00a0vitamin D toxicity from inappropriate practice","volume":"84","author":"Taylor","year":"2018","journal-title":"Br J Clin Pharmacol"},{"issue":"7","key":"2024012918213550200_R2","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.1210\/jc.2011-0385","article-title":"Evaluation, treatment, and\u00a0prevention of\u00a0vitamin D deficiency: an endocrine society clinical practice guideline","volume":"96","author":"Holick","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"2024012918213550200_R3","volume-title":"Dietary Reference Intakes for Calcium and Vitamin D","author":"Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and calcium","year":"2011"},{"issue":"3","key":"2024012918213550200_R4","doi-asserted-by":"publisher","first-page":"125","DOI":"10.4103\/0971-4065.43693","article-title":"Vitamin D intoxication presenting as acute renal failure","volume":"18","author":"Naik","year":"2008","journal-title":"Indian J Nephrol"},{"key":"2024012918213550200_R5","article-title":"5 reasons you need to take vitamin D this winter","volume-title":"Men\u2019s Health","author":"Roberts","year":"2017"},{"key":"2024012918213550200_R6","article-title":"8 proven ways to increase testosterone levels naturally","volume-title":"Healthline","author":"Mawer","year":"2016"},{"key":"2024012918213550200_R7","article-title":"Vitamin D increases testosterone production","volume-title":"Science News","author":"Sj\u00f8gren","year":"2020"},{"key":"2024012918213550200_R8","article-title":"7 best supplements to boost testosterone levels, according to a dietitian","author":"Ajmera","year":"2022"},{"key":"2024012918213550200_R9","article-title":"Boosting testosterone naturally","volume-title":"Life Extension","author":"Aziz","year":"2021"},{"issue":"03","key":"2024012918213550200_R10","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1055\/s-0030-1269854","article-title":"Effect of\u00a0vitamin D supplementation on\u00a0testosterone levels in\u00a0men","volume":"43","author":"Pilz","year":"2011","journal-title":"Horm Metab Res"},{"issue":"5","key":"2024012918213550200_R11","doi-asserted-by":"publisher","first-page":"1321","DOI":"10.3945\/ajcn.2008.27004","article-title":"Vitamin D supplementation enhances the beneficial effects of\u00a0weight loss on\u00a0cardiovascular disease risk markers","volume":"89","author":"Zittermann","year":"2009","journal-title":"Am J Clin Nutr"},{"issue":"5","key":"2024012918213550200_R12","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1093\/humrep\/deq024","article-title":"Vitamin D receptor and\u00a0vitamin D metabolizing enzymes are expressed in\u00a0the human male reproductive tract","volume":"25","author":"Blomberg Jensen","year":"2010","journal-title":"Hum Reprod"},{"issue":"6","key":"2024012918213550200_R13","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1210\/er.2008-0004","article-title":"Vitamin D and\u00a0human health: lessons from vitamin d receptor null mice","volume":"29","author":"Bouillon","year":"2008","journal-title":"Endocr Rev"},{"issue":"1","key":"2024012918213550200_R14","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s12020-020-02482-3","article-title":"Relationship of\u00a0vitamin D status with testosterone levels: a systematic review and\u00a0meta-analysis","volume":"72","author":"D\u2019Andrea","year":"2021","journal-title":"Endocrine"},{"issue":"11","key":"2024012918213550200_R15","doi-asserted-by":"publisher","first-page":"3495","DOI":"10.1093\/jn\/nxab239","article-title":"Prevalence of\u00a0and factors associated with dietary supplement use in\u00a0a stratified, random sample of\u00a0us military personnel: the us military dietary supplement use study","volume":"151","author":"Knapik","year":"2021","journal-title":"J Nutr"},{"issue":"4","key":"2024012918213550200_R16","doi-asserted-by":"publisher","first-page":"985","DOI":"10.3945\/ajcn.2010.29274","article-title":"Use of\u00a0dietary supplements among active-duty US Army soldiers","volume":"92","author":"Lieberman","year":"2010","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"2024012918213550200_R17","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-14-143","article-title":"A systematic review and\u00a0meta-analysis on\u00a0the prevalence of\u00a0dietary supplement use by military personnel","volume":"14","author":"Knapik","year":"2014","journal-title":"BMC Complement Altern Med"},{"issue":"7","key":"2024012918213550200_R18","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-250553","article-title":"Vitamin D intoxication and\u00a0severe hypercalcaemia complicating nutritional supplements misuse","volume":"15","author":"Alkundi","year":"2022","journal-title":"BMJ Case Rep"},{"issue":"1","key":"2024012918213550200_R19","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-020-01614-8","article-title":"Exogenous intoxication by non-prescribed use of\u00a0vitamin D, a case report","volume":"20","author":"de Paula","year":"2020","journal-title":"BMC Geriatr"}],"container-title":["Military Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/milmed\/article-pdf\/189\/1-2\/e417\/56448626\/usad237.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/milmed\/article-pdf\/189\/1-2\/e417\/56448626\/usad237.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T18:23:13Z","timestamp":1706552593000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/milmed\/article\/189\/1-2\/e417\/7218964"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,4]]},"references-count":19,"journal-issue":{"issue":"1-2","published-online":{"date-parts":[[2023,7,4]]},"published-print":{"date-parts":[[2024,1,23]]}},"URL":"https:\/\/doi.org\/10.1093\/milmed\/usad237","relation":{},"ISSN":["0026-4075","1930-613X"],"issn-type":[{"value":"0026-4075","type":"print"},{"value":"1930-613X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1,1]]},"published":{"date-parts":[[2023,7,4]]}}}