{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:22:20Z","timestamp":1762957340450,"version":"3.37.3"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"Supplement_3","license":[{"start":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T00:00:00Z","timestamp":1724025600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,19]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a temporizing hemorrhage control intervention, but its inevitable effect on time to operating room (OR) has not been assessed. The aim of our study is to assess the impact of undergoing REBOA before surgery (RBS) on time to definitive hemorrhage control surgery.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>In this retrospective analysis of 2017\u20132021 ACS-TQIP database, all adult (\u226518\u2009years) patients who underwent emergency hemorrhage control laparotomy (\u22644\u2009hours of admission) and received early blood products (\u22644\u2009hours) were included, and patients with severe head injury (Head-abbreviated injury score\u2009&amp;gt;\u20092) were excluded. Patients were stratified into those who did (RBS) vs those who did not undergo REBOA before surgery (No-RBS). Primary outcome was time to laparotomy. Secondary outcomes were complications and mortality. Multivariable linear and binary logistic regression analyses were performed to identify the independent associations between RBS and outcomes.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 32,683 patients who underwent emergency laparotomy were identified (RBS: 342; No-RBS: 32,341). The mean age was 39 (16) years, 78% were male, mean SBP was 107 (34) mmHg, and the median injury severity score was 21 [14\u201329]. The median time to emergency hemorrhage control surgery was 50 [32\u201385] minutes. Overall complication rate was 16% and mortality was 19%. On univariate analysis, RBS group had longer time to surgery (RBS 56 [41\u201389] vs No-RBS 50 [32\u201385] minutes, P\u2009&amp;lt;\u20090.001). On multivariable analysis, RBS was independently associated with a longer time to hemorrhage control surgery (\u03b2\u2009+\u200914.5 [95%CI 7.8\u201321.3], P\u2009&amp;lt;\u20090.001), higher odds of complications (aOR\u2009=\u20091.72, 95%CI\u2009=\u20091.27\u20132.34, P\u2009&amp;lt;\u20090.001), and mortality (aOR\u2009=\u20093.42, 95%CI\u2009=\u20092.57\u20134.55, P\u2009&amp;lt;\u20090.001).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>REBOA is independently associated with longer time to OR for hemorrhaging trauma patients with an average delay of 15\u2009minutes. Further research evaluating center-specific REBOA volume and utilization practices, and other pertinent system factors, may help improve both time to REBOA as well as time to definitive hemorrhage control across US trauma centers.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Level of Evidence<\/jats:title>\n                  <jats:p>III<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Study Type<\/jats:title>\n                  <jats:p>Epidemiologic<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/milmed\/usae089","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T16:34:33Z","timestamp":1724085273000},"page":"262-267","source":"Crossref","is-referenced-by-count":4,"title":["When Every Minute Counts: REBOA Before Surgery Is Independently Associated With a 15-Minute Delay in Time to Definitive Hemorrhage Control"],"prefix":"10.1093","volume":"189","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4722-2984","authenticated-orcid":false,"given":"Christina","family":"Colosimo","sequence":"first","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0893-6204","authenticated-orcid":false,"given":"Sai Krishna","family":"Bhogadi","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Hejazi","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam","family":"Nelson","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7694-1884","authenticated-orcid":false,"given":"Hamidreza","family":"Hosseinpour","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Collin","family":"Stewart","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Audrey L","family":"Spencer","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Ditillo","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louis J","family":"Magnotti","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bellal","family":"Joseph","sequence":"additional","affiliation":[{"name":"Division of Trauma, Critical Care, Burns, and Emergency Surgery, Department of Surgery, College of Medicine, University of Arizona , Tucson, AZ 85724, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,8,19]]},"reference":[{"issue":"3","key":"2024082004055795900_R1","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1186\/s40779-020-00241-z","article-title":"Prehospital hemorrhage control and REBOA","volume":"5","author":"Campion","year":"2019","journal-title":"Curr Trauma Rep"},{"issue":"1","key":"2024082004055795900_R2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13017-018-0181-6","article-title":"The complications associated with resuscitative endovascular balloon occlusion of the aorta (REBOA)","volume":"13","author":"Ribeiro 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report","volume":"13","author":"\u00d6zkurtul","year":"2019","journal-title":"Patient Saf Surg"},{"issue":"19","key":"2024082004055795900_R12","doi-asserted-by":"publisher","first-page":"1862","DOI":"10.1001\/jama.2023.20850","article-title":"Emergency department resuscitative endovascular balloon occlusion of the aorta in trauma patients with exsanguinating hemorrhage: the UK-REBOA randomized clinical trial","volume":"330","author":"Jansen","year":"2023","journal-title":"JAMA"},{"issue":"2","key":"2024082004055795900_R13","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1097\/TA.0000000000002773","article-title":"Resuscitative endovascular balloon of the aorta is feasible in penetrating chest trauma with major hemorrhage: proposal of a new institutional deployment algorithm","volume":"89","author":"Ordo\u00f1ez","year":"2020","journal-title":"J Trauma Acute Care 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