{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T12:35:50Z","timestamp":1782995750281,"version":"3.54.5"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"11-12","license":[{"start":{"date-parts":[[2024,3,30]],"date-time":"2024-03-30T00:00:00Z","timestamp":1711756800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>A rise in tinea cruris among Thai Naval Cadets has been observed. Clotrimazole powder has been shown to be effective as an adjunct treatment for tinea cruris; however, its efficacy as a monotherapy is limited.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The aim is to determine the efficacy of 1% clotrimazole cream versus 1% clotrimazole powder in treating tinea cruris.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Material and Methods<\/jats:title>\n                  <jats:p>A randomized trial was conducted at the Thai Naval Rating School, Chonburi, Thailand. Naval rating cadets with suspected tinea cruris were randomly assigned to one of two groups: 1% clotrimazole cream or 1% clotrimazole powder, and they were instructed to apply the related medication to the affected lesion twice daily for 4\u2009weeks. Clinical and symptomatic evaluations were carried out at 4 and 8\u2009weeks.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>All 17 and 14 participants who received 1% clotrimazole cream and powder, respectively, were included. After 4\u2009weeks, the clinical cure rates were 76.5% in the cream group and 85.7% in the powder group (P\u2009=\u2009.664). All participants were clinically cured within 8\u2009weeks. The self-evaluation of itch severity using a visual analog scale (VAS) revealed no significant difference between the two groups (P\u2009=\u2009.343). The dermatology quality of life index decreased as clinical improvement was achieved in both the clotrimazole cream and powder groups (6.0 vs. 7.5 score reductions, respectively; P\u2009=\u2009.765). The score for sweat reduction was higher in the 1% clotrimazole powder group compared to the cream group (5.0 vs. 4.0, respectively; P\u2009=\u2009.006).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Monotherapy with 1% clotrimazole powder showed comparable efficacy to 1% clotrimazole cream. Furthermore, the powder treatment reduced sweat more effectively compared to the cream.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/milmed\/usae105","type":"journal-article","created":{"date-parts":[[2024,3,30]],"date-time":"2024-03-30T16:25:26Z","timestamp":1711815926000},"page":"e2494-e2498","source":"Crossref","is-referenced-by-count":4,"title":["Efficacy of 1% Clotrimazole Powder Monotherapy for Treating Tinea Cruris: A Comparative Randomized Study"],"prefix":"10.1093","volume":"189","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3266-0700","authenticated-orcid":false,"given":"Punyawee","family":"Ongsri","sequence":"first","affiliation":[{"name":"Division of Dermatology, Department of Internal Medicine, Somdech Phra Nangchao Sirikit Hospital, Naval medical department, Royal Thai Navy , Sattahip, Chonburi Province 20180,","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanchaya Na","family":"Bangchang","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Internal Medicine, Somdech Phra Nangchao Sirikit Hospital, Naval medical department, Royal Thai Navy , Sattahip, Chonburi Province 20180,","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phuwakorn","family":"Saengthong-Aram","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University , Bangkoknoi, Bangkok 10700,","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charussri","family":"Leeyaphan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University , Bangkoknoi, Bangkok 10700,","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penvadee","family":"Pattanaprichakul","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University , Bangkoknoi, Bangkok 10700,","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumanas","family":"Bunyaratavej","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University , Bangkoknoi, Bangkok 10700,","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,3,30]]},"reference":[{"issue":"2","key":"2024110620113338500_R1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/07853890.2023.2267425","article-title":"A review of skin disease in military soldiers: challenges and potential solutions","volume":"55","author":"Singal","year":"2023","journal-title":"Ann Med"},{"issue":"10","key":"2024110620113338500_R2","doi-asserted-by":"publisher","first-page":"1248","DOI":"10.3346\/jkms.2012.27.10.1248","article-title":"Prevalence of 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