{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T16:39:42Z","timestamp":1769272782303,"version":"3.49.0"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Recurrent aphthous stomatitis (RAS) is a common condition that can significantly impact a patient\u2019s quality of life. Despite extensive research, its etiology remains unclear, though it is believed to be multifactorial. Vitamin D plays a crucial role in modulating innate and adaptive immune responses, making it a potential factor in RAS pathogenesis, which may be linked to immune dysfunction. This study aims to investigate the association between vitamin D deficiency and RAS in a North American military-centric population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A total of 92 subjects were included: 46 with RAS and 46 without a history of aphthous lesions. Demographic data, including age, gender, and ethnicity, were recorded. Serum vitamin D levels were measured using electrochemiluminescence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean serum vitamin D level in the RAS group was 23.7\u00b19.4 ng\/mL, while the control group had a mean level of 21.6\u00b19.5 ng\/mL. Both groups were vitamin D deficient, and no statistically significant difference was found between them. Although no differences were observed regarding age and ethnicity, a significant difference was noted based on gender.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Serum vitamin D levels did not differ significantly between individuals with and without RAS. These findings suggest that vitamin D deficiency alone may not be a determining factor in RAS pathogenesis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/milmed\/usaf213","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T07:39:11Z","timestamp":1746689951000},"page":"e47-e51","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Vitamin D Levels in a Military Associated Population With Recurrent Aphthous Stomatitis"],"prefix":"10.1093","volume":"191","author":[{"given":"Nathan D","family":"Krivitzky","sequence":"first","affiliation":[{"name":"88th Dental Squadron, Wright-Patterson AFB , OH 45433,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Casey M","family":"Slack","sequence":"additional","affiliation":[{"name":"Advanced Education in General Dentistry Residency, 88th Dental Squadron, Wright-Patterson AFB , OH 45433,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amar","family":"Kosaraju","sequence":"additional","affiliation":[{"name":"DC & MSC Utilization & Education Branch, AFPC\/DPMND, Joint Base San Antonio-Randolph , TX 78150,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6432-1274","authenticated-orcid":false,"given":"Kraig S","family":"Vandewalle","sequence":"additional","affiliation":[{"name":"Advanced Education in General Dentistry Residency, 59th Dental Squadron, Joint-Base San Antonio, Lackland , TX 78236,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"2026012303265796300_usaf213-B1","doi-asserted-by":"publisher","first-page":"e794","DOI":"10.1002\/cre2.794","article-title":"Serum level of vitamin D in patients with recurrent aphthous stomatitis: a systematic review and meta-analysis of case control studies","volume":"10","author":"Safari-Faramani","year":"2024","journal-title":"Clin Exp Dent Res"},{"key":"2026012303265796300_usaf213-B2","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/s0738-081x(00)00147-4","article-title":"Recurrent aphthous stomatitis","volume":"18","author":"Porter","year":"2000","journal-title":"Clin Dermatol"},{"key":"2026012303265796300_usaf213-B3","doi-asserted-by":"publisher","first-page":"217","DOI":"10.2147\/CCIDE.S369481","article-title":"\u00adRecurrent aphthous stomatitis affects quality of life. 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