{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T18:04:47Z","timestamp":1773252287801,"version":"3.50.1"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"3-4","funder":[{"name":"Global Emerging Infectious Surveillance"},{"DOI":"10.13039\/100014035","name":"Armed Forces Health Surveillance Branch","doi-asserted-by":"publisher","award":["P0133_22_NM"],"award-info":[{"award-number":["P0133_22_NM"]}],"id":[{"id":"10.13039\/100014035","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Lyme disease is caused by Borrelia burgdorferi sensu lato that is transmitted through the bite of infectious ticks. Within the US active duty military component, Lyme is the most frequently reported vector-borne disease. There have not been reports on Lyme disease prevalence in Central America, but reports of travelers who contracted rickettsiosis after their trip to Honduras suggest a need for an increased tick-borne disease surveillance, including Lyme disease. The aim of this study is to determine the prevalence of Lyme disease in US military personnel deployed to Honduras.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A retrospective cohort study was designed using pre- and postdeployment sera from 1,640 US military personnel who had been stationed in Honduras for at least 6 months between 2000 and 2021. All postdeployment sera were screened for the presence of IgG antibodies against B. burgdorferi by ELISA (enzyme-linked immunosorbent assay) followed by testing the predeployment sera of individuals with positive postdeployment samples to determine seroconversion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The postdeployment seropositivity in US military personnel for IgG antibodies against B. burgdorferi was 1.3% (22\/1,640) with 0.4% (6\/1,640) individuals seroconverted. These results also indicate that 16 US military personnel were exposed to B. burgdorferi before their assignment to Honduras, perhaps because of previous exposure to B. burgdorferi at home.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The 0.4% rate of seroconversion suggested a low-risk threat. Additional testing of potential vectors for B. burgdorferi in the regions would be beneficial to inform active and effective vector control countermeasures in the region to prevent exposure.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/milmed\/usaf216","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T07:40:35Z","timestamp":1746690035000},"page":"e470-e473","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of Lyme Seroconversion Among US Military Personnel in Honduras"],"prefix":"10.1093","volume":"191","author":[{"given":"Hua-Wei","family":"Chen","sequence":"first","affiliation":[{"name":"Naval Medical Research Command , Silver Spring, MD 20910,","place":["United States"]},{"name":"Henry M. Jackson Foundation for the Advancement of Military Medicine , Bethesda, MD 20817,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor A","family":"Sugiharto","sequence":"additional","affiliation":[{"name":"Naval Medical Research Command , Silver Spring, MD 20910,","place":["United States"]},{"name":"Henry M. Jackson Foundation for the Advancement of Military Medicine , Bethesda, MD 20817,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie K","family":"Gatrell","sequence":"additional","affiliation":[{"name":"Naval Medical Research Command , Silver Spring, MD 20910,","place":["United States"]},{"name":"Leidos Inc , Reston, VA 20190,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabrielle R","family":"Blazek","sequence":"additional","affiliation":[{"name":"Naval Medical Research Command , Silver Spring, MD 20910,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda M","family":"Cherry","sequence":"additional","affiliation":[{"name":"Naval Medical Research Command , Silver Spring, MD 20910,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark P","family":"Simons","sequence":"additional","affiliation":[{"name":"Naval Medical Research Command , Silver Spring, MD 20910,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah A","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Uniformed Services University of the Health Sciences , Bethesda, MD 20814,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0588-8005","authenticated-orcid":false,"given":"Megan A","family":"Schilling","sequence":"additional","affiliation":[{"name":"Naval Medical Research Command , Silver Spring, MD 20910,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,6,9]]},"reference":[{"key":"2026031018434524500_usaf216-B1","first-page":"23","article-title":"Surveillance snapshot: Lyme disease among beneficiaries of the Military Health System, 2001\u20132012","volume":"20","author":"Armed Forces Health Surveillance Center","year":"2013","journal-title":"MSMR"},{"key":"2026031018434524500_usaf216-B2","first-page":"e28","article-title":"Prevalence of Lyme Disease Attributable to Military Service at the USMA, West Point NY: FY2016-2018","volume":"185","author":"Schubert","year":"2020","journal-title":"Mil Med"},{"key":"2026031018434524500_usaf216-B3","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.3201\/eid1508.090172","article-title":"Tick-borne rickettsiosis in traveler returning from Honduras","volume":"15","author":"Chen","year":"2009","journal-title":"Emerg Infect Dis"},{"key":"2026031018434524500_usaf216-B4","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1093\/milmed\/usab120","article-title":"Leptospirosis and Rickettsial diseases sero-conversion surveillance among U.S. military personnel in Honduras","volume":"187","author":"Chao","year":"2022","journal-title":"Mil Med"},{"key":"2026031018434524500_usaf216-B5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.55460\/13SQ-OK4V","article-title":"Zoonotic and infectious disease surveillance in Central America: Honduran feral cats positive for toxoplasma, trypanosoma, leishmania, rickettsia, and Lyme disease","volume":"10","author":"Mccown","year":"2010","journal-title":"J Spec Oper Med"},{"key":"2026031018434524500_usaf216-B6","doi-asserted-by":"crossref","first-page":"435","DOI":"10.4067\/s0716-10182023000400435","article-title":"Cerebellar syndrome associated to Lyme neuroborreliosis: case report","volume":"40","author":"Aguilar-Andino","year":"2023","journal-title":"Rev Chilena Infectol"},{"key":"2026031018434524500_usaf216-B7","author":"Duffin"},{"key":"2026031018434524500_usaf216-B8","doi-asserted-by":"crossref","first-page":"194","DOI":"10.14745\/ccdr.v40i11a01","article-title":"Lyme disease: clinical diagnosis and treatment","volume":"40","author":"Hatchette","year":"2014","journal-title":"Can Commun Dis Rep"},{"key":"2026031018434524500_usaf216-B9","doi-asserted-by":"crossref","first-page":"427","DOI":"10.2147\/IJGM.S122313","article-title":"Commercial test kits for detection of Lyme borreliosis: a meta-analysis of test accuracy","volume":"9","author":"Cook","year":"2016","journal-title":"Int J Gen Med"}],"container-title":["Military 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