{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T09:36:39Z","timestamp":1648978599003},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3-4","license":[{"start":{"date-parts":[[2019,10,28]],"date-time":"2019-10-28T00:00:00Z","timestamp":1572220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>In the French armed forces, the biological checkup required during the recruitment process comprises a urinalysis (urinary dipstick), a complete blood count (CBC), and measurement of serum levels of aspartate aminotransferase, alanine aminotransferase, fasting blood glucose, and creatinine. This study aimed to evaluate the benefits of this biological checkup and to determine the most relevant parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>We conducted a monocentric retrospective study of all standardized and systematically conducted blood tests (CBC and measurement of aspartate aminotransferase, alanine aminotransferase, fasting blood glucose, and creatinine) over a 15-month period among 726 French Army recruits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The population included mainly young males (85.4%, mean age 21.6\u00a0years). More than half (54.1%) of the blood tests had at least one abnormal parameter, most often concerning the CBC. Anemia occurred in 5.3% of the population and was mostly normocytic. Microcytosis was mostly not associated with anemia (72.3% of cases). Lymphopenia occurred in 20.1% of the population and was mostly mild. Eosinophilia was present in 5.1% of the population and was never severe. Thrombocytopenia occurred in 0.7% of the population and was never severe. Serum levels of aminotransferases were elevated in 8.1% of the population. Fasting plasma glucose averaged 84\u00a0mg\/dL (SD: 0.07) ranging from 64 to 123\u00a0mg\/dL, was abnormal in 0.4% of the population, and one case of diabetes was diagnosed. Serum creatinine concentration was elevated in 0.7% of the population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CBCs gave useful information but iron deficiency was common and insufficiently detected by this single analysis. Assessing aminotransferase levels without screening for viral hepatitis and systematic measurement of fasting plasma glucose levels did not appear to be efficient. In addition, the only interest in systematic measurement of creatinine serum levels was to obtain a reference level for long-term follow-up. In addition to the urinary dipstick, the systematic biological checkup at recruitment could be limited to a CBC with measurement of plasma ferritin levels and Hepatitis B virus serology, providing that any CBC abnormalities, in particular cytopenia, eosinophilia, and microcytosis, are systematically investigated. For a public health approach, systematic screening for other sexually transmitted infections could be proposed.<\/jats:p><\/jats:sec>","DOI":"10.1093\/milmed\/usz368","type":"journal-article","created":{"date-parts":[[2019,10,30]],"date-time":"2019-10-30T18:51:16Z","timestamp":1572461476000},"page":"346-353","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Systematic Blood Testing at the Time of Recruitment to the Armed Forces: Retrospective Monocentric Study Among 726 French Army Soldiers"],"prefix":"10.1093","volume":"185","author":[{"given":"Weniko","family":"Car\u00e9","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Percy Military Teaching Hospital, 101 Boulevard Henri Barbusse, 92140 Clamart, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"H\u00e9nard","sequence":"first","affiliation":[{"name":"Third Military Medical Center, Quartier Saint Ruth, Rue de la Porte d\u2019Ypres, 59000 Lille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Gillard","sequence":"first","affiliation":[{"name":"Surgeon General Office, Operations Division, Fort Neuf de Vincennes, Cours des Mar\u00e9chaux, 75614 Paris Cedex 12, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serge","family":"Cremades","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, B\u00e9gin Military Teaching Hospital, 69 Avenue de Paris, 94160 Saint-Mand\u00e9, France"},{"name":"Val-de-Gr\u00e2ce School, 1 Place Alphonse Laveran, 75005 Paris, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franck","family":"Ceppa","sequence":"first","affiliation":[{"name":"Val-de-Gr\u00e2ce School, 1 Place Alphonse Laveran, 75005 Paris, France"},{"name":"Department of Biology, B\u00e9gin Military Teaching Hospital, 69 Avenue de Paris, 94160 Saint-Mand\u00e9, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Vest","sequence":"first","affiliation":[{"name":"Department of Biology, Percy Military Teaching Hospital, 101 Avenue Henri Barbusse, 92140 Clamart, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Foissaud","sequence":"first","affiliation":[{"name":"Department of Biology, Percy Military Teaching Hospital, 101 Avenue Henri Barbusse, 92140 Clamart, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carine","family":"Hejl","sequence":"first","affiliation":[{"name":"Department of Biology, Percy Military Teaching Hospital, 101 Avenue Henri Barbusse, 92140 Clamart, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,10,28]]},"reference":[{"key":"2020040714053530200_ref1","author":"U.S. Army"},{"key":"2020040714053530200_ref2","volume-title":"Decreto n. 13 del 13 febbraio 2008-deficit di G6PD","author":"Attrition","year":"2008"},{"key":"2020040714053530200_ref3","volume-title":"Lettre N\u00b00419\/DEF\/DCSSA\/PC\/MA du 25 janvier 2013 relative aux arr\u00eat\u00e9s r\u00e9glementant l'aptitude m\u00e9dicale du personnel militaire","author":"Attrition","year":"2013"},{"key":"2020040714053530200_ref4","volume-title":"Arr\u00eat\u00e9 du 20 d\u00e9cembre 2012 relatif \u00e0 la d\u00e9termination et au contr\u00f4le de l\u2019aptitude m\u00e9dicale \u00e0 servir du personnel militaire","author":"Military Attrition","year":"2013"},{"key":"2020040714053530200_ref5","volume-title":"Lecture critique de l'h\u00e9mogramme: valeurs seuils \u00e0 reconna\u00eetre comme probablement pathologiques et principales variations non pathologiques","author":"Service des R\u00e9f\u00e9rences M\u00e9dicales","year":"1997"},{"key":"2020040714053530200_ref6","volume-title":"Reference Ranges for Adults and Children-pre-analytical considerations","author":"Heil","year":"2008","edition":"Ed 9"},{"issue":"6","key":"2020040714053530200_ref7","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. 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