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While catecholamines can aggravate sepsis-induced immune dysfunction and modulate bacterial virulence traits, their impact on fungal pathogenicity is poorly understood. Using IncuCyte time-lapse microscopy and a fruit fly candidiasis model, we studied growth rates, morphogenesis, stress tolerance, and virulence of C. albicans cocultured with epinephrine and norepinephrine. We found that pharmacologically attainable catecholamine serum concentrations caused minimal changes to in vitro growth kinetics, filamentation, and fungal resistance to thermal or oxidative stress. Similarly, exposure of C. albicans to catecholamines did not alter the survival of infected flies.<\/jats:p>","DOI":"10.1093\/mmy\/myaa060","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T11:24:22Z","timestamp":1593516262000},"page":"102-105","source":"Crossref","is-referenced-by-count":0,"title":["Pharmacological serum concentrations of epinephrine and norepinephrine do not affect growth rate, morphogenesis, stress tolerance, and virulence of<i>Candida albicans<\/i>"],"prefix":"10.1093","volume":"59","author":[{"given":"Sebastian","family":"Wurster","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Infection Control and Employee Health; The University of Texas M.D. Anderson Cancer Center; Houston, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Lyos","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Infection Control and Employee Health; 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