{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:11:19Z","timestamp":1757704279960,"version":"3.41.2"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T00:00:00Z","timestamp":1647993600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:label\/>\n                  <jats:p>Geotrichum spp. is an emergent pathogen. We aimed to describe Geotrichum spp. invasive fungal infections (IFI) in patients from Mexico. We reviewed cases with Geotrichum spp. isolated in clinical samples, from 2001 to 2019. Descriptive analysis was used for clinical data. Twenty patients with proven\/probable Geotrichum spp. IFI were analyzed. The median age was 43; 55% were males. Hematologic malignancy was found in 60% (12\/20); 75% (15\/20) received systemic immunosuppressors. The most common presentation was lower respiratory tract infection. In-hospital mortality was 45% (9\/20). Geotrichum spp. should be acknowledged as a pathogen causing atypical pneumonia in immunocompromised Latin American patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Lay Summary<\/jats:title>\n                  <jats:p>Geotrichum spp. causes invasive infection in immunocompromised hosts. We describe a case series of 20 patients from Mexico City. Hematologic malignancy was the most common comorbidity. Clinical presentation was mainly lower respiratory tract infection. Mortality was high despite antifungal therapy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mmy\/myac022","type":"journal-article","created":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T20:24:02Z","timestamp":1647548642000},"source":"Crossref","is-referenced-by-count":3,"title":["<i>Geotrichum<\/i> spp: An overlooked and fatal etiologic agent in immunocompromised patients. A case series from a referral center in Mexico"],"prefix":"10.1093","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7809-9619","authenticated-orcid":false,"given":"Sandra","family":"Rajme-L\u00f3pez","sequence":"first","affiliation":[{"name":"Infectious Diseases\/Clinical Microbiology Laboratory, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n \u201cSalvador Zubir\u00e1n\u201d"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda F","family":"Gonz\u00e1lez-Lara","sequence":"additional","affiliation":[{"name":"Infectious Diseases\/Clinical Microbiology Laboratory, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n \u201cSalvador Zubir\u00e1n\u201d"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R Areli","family":"Mart\u00ednez-Gamboa","sequence":"additional","affiliation":[{"name":"Clinical Microbiology Laboratory, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n \u201cSalvador Zubir\u00e1n\u201d"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Rangel-Cordero","sequence":"additional","affiliation":[{"name":"Clinical Microbiology Laboratory, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n \u201cSalvador Zubir\u00e1n\u201d"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo","family":"Ponce-de-Le\u00f3n","sequence":"additional","affiliation":[{"name":"Infectious Diseases\/Clinical Microbiology Laboratory, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n \u201cSalvador Zubir\u00e1n\u201d"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,3,23]]},"reference":[{"key":"2022040911124432400_bib1","first-page":"489","article-title":"Ribosomal gene phylogeny and species delimitation in Geotrichum and its teleomorphs","volume":"50","author":"de Hoog","year":"2004","journal-title":"Studies Mycol"},{"key":"2022040911124432400_bib2","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/myc.12595","article-title":"Invasive infections due to Saprochaete and Geotrichum species: report of 23 cases from the FungiScope Registry","volume":"60","author":"Duran Graeff","year":"2017","journal-title":"Mycoses"},{"key":"2022040911124432400_bib3","first-page":"1279","article-title":"MTS","volume-title":"Geotrichum","author":"Sybren de Hoog","year":"2011"},{"key":"2022040911124432400_bib4","first-page":"2491","article-title":"Identification of medically relevant species of arthroconidial yeasts by use of matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry","volume-title":"J Clin Microbiol","author":"Kolecka","year":"2013"},{"key":"2022040911124432400_bib5","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1128\/JCM.43.4.1818-1828.2005","article-title":"Invasive infections caused by Trichosporon species and Geotrichum capitatumin patients with hematological malignancies: a retrospective multicenter study from Italy and review of the literature","volume":"43","author":"Girmenia","year":"2005","journal-title":"J Clin Microbiol"},{"key":"2022040911124432400_bib6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.riam.2013.02.004","article-title":"Invasive infections caused by Saprochaete capitata in patients with haematological malignancies: Report of five cases and review of the antifungal therapy","volume":"30","author":"Garc\u00eda-Ruiz","year":"2013","journal-title":"Revista Iberoamericana de Micolog\u00eda"},{"key":"2022040911124432400_bib7","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.3109\/10428194.2013.820290","article-title":"Concomitant cases of disseminated Geotrichum clavatum infections in patients with acute myeloid leukemia","volume":"55","author":"Picard","year":"2014","journal-title":"Leukemia Lymphoma"},{"key":"2022040911124432400_bib8","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/myc.12508","article-title":"A cluster of Geotrichum clavatum (Saprochaete clavata) infection in haematological patients: a first Italian report and review of literature","volume":"59","author":"Del Principe","year":"2016","journal-title":"Mycoses"},{"key":"2022040911124432400_bib9","first-page":"24","article-title":"Geotricosis pulmonar en una paciente con trasplante renal. 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