{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T09:30:43Z","timestamp":1768037443113,"version":"3.49.0"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T00:00:00Z","timestamp":1672272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,12,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Reports of orthopedic fungal infections caused by Trichosporon species are extremely scarce, thus we aimed to describe a case series and review the cases published in the literature. Patients were retrospectively included if a previous culture of bone, joint, or soft tissues had resulted positive for Trichosporon species along with a clinical diagnosis of an orthopedic infection. Eight patients were included with diverse orthopedic conditions, most of them cases of osteomyelitis. The main isolated species was Trichosporon asahii. All patients were treated with antifungals, mainly voriconazole, and surgical management, resulting in high rates of clinical improvement and low associated mortality.<\/jats:p>","DOI":"10.1093\/mmy\/myad001","type":"journal-article","created":{"date-parts":[[2023,1,8]],"date-time":"2023-01-08T01:16:36Z","timestamp":1673140596000},"source":"Crossref","is-referenced-by-count":5,"title":["Orthopedic infections due to <i>Trichosporon<\/i> species: Case series and literature review"],"prefix":"10.1093","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6311-9434","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Mello L\u00f3pez","sequence":"first","affiliation":[{"name":"Departamento de Mol\u00e9stias Infecciosas e Parasit\u00e1rias, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz Alves","family":"da Silva Neto","sequence":"additional","affiliation":[{"name":"Instituto de Ortopedia e Traumatologia, Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , S\u00e3o Paulo , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2097-389X","authenticated-orcid":false,"given":"V\u00edtor Falc\u00e3o","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Departamento de Mol\u00e9stias Infecciosas e Parasit\u00e1rias, Faculdade de Medicina da Universidade de S\u00e3o Paulo , S\u00e3o Paulo , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir Cordeiro","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Instituto de Ortopedia e Traumatologia, Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , S\u00e3o Paulo , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscila Rosalba Domingos","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Instituto de Ortopedia e Traumatologia, Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , S\u00e3o Paulo , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L\u00facia Lei Munhoz","family":"Lima","sequence":"additional","affiliation":[{"name":"Instituto de Ortopedia e Traumatologia, Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de S\u00e3o Paulo , S\u00e3o Paulo , Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,1,4]]},"reference":[{"key":"2023011810330052400_bib1","doi-asserted-by":"crossref","first-page":"909.e1","DOI":"10.1016\/j.cmi.2019.03.026","article-title":"Species distribution and antifungal susceptibility of 358 Trichosporon clinical isolates collected in 24 medical centres","volume":"25","author":"Francisco","year":"2019","journal-title":"Clin Microbiol Infect"},{"key":"2023011810330052400_bib2","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1128\/CMR.00003-11","article-title":"Current knowledge of Trichosporon spp. and trichosporonosis","volume":"24","author":"Colombo","year":"2011","journal-title":"Clin Microbiol Rev"},{"key":"2023011810330052400_bib3","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1439-0507.2009.01709.x","article-title":"Poststernotomy sternal osteomyelitis and mediastinitis by Trichosporon asahii: a rare occurrence with a grave prognosis","volume":"53","author":"Baraboutis","year":"2010","journal-title":"Mycoses"},{"key":"2023011810330052400_bib4","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.3389\/fmicb.2016.01629","article-title":"Invasive Trichosporon infection: a systematic review on a re-emerging fungal pathogen","volume":"7","author":"de Almeida J\u00fanior","year":"2016","journal-title":"Front Microbiol"},{"key":"2023011810330052400_bib5","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1093\/jac\/dkab085","article-title":"Epidemiology, clinical aspects, outcomes and prognostic factors associated with Trichosporon fungaemia: results of an international multicentre study carried out at 23 medical centres","volume":"76","author":"Nobrega de Almeida","year":"2021","journal-title":"J Antimicrob Chemother"},{"key":"2023011810330052400_bib6","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1128\/AAC.00556-06","article-title":"Biofilm formation by the emerging fungal pathogen Trichosporon asahii: development, architecture, and antifungal resistance","volume":"50","author":"Di Bonaventura","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"2023011810330052400_bib7","doi-asserted-by":"crossref","first-page":"390","DOI":"10.5435\/JAAOS-22-06-390","article-title":"Fungal osteomyelitis and septic arthritis","volume":"22","author":"Bariteau","year":"2014","journal-title":"J Am Acad Orthop Surg"},{"key":"2023011810330052400_bib8","doi-asserted-by":"crossref","first-page":"e375","DOI":"10.1016\/S1473-3099(21)00203-6","article-title":"Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM","volume":"21","author":"Chen","year":"2021","journal-title":"Lancet Infect Dis"},{"key":"2023011810330052400_bib9","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1093\/infdis\/151.3.566","article-title":"Fatal fungemia with arthritic involvement caused by Trichosporon beigelii in a bone marrow transplant recipient","volume":"151","author":"Gardella","year":"1985","journal-title":"J Infect Dis"},{"key":"2023011810330052400_bib10","doi-asserted-by":"crossref","first-page":"245","DOI":"10.3109\/00365549209052620","article-title":"Successful surgical management of septic arthritis due to Trichosporon beigelii in a patient with acute myeloid leukaemia","volume":"24","author":"McWhinney","year":"1992","journal-title":"Scand J Infect Dis"},{"key":"2023011810330052400_bib11","doi-asserted-by":"crossref","first-page":"E116","DOI":"10.1097\/BRS.0b013e3181642a7c","article-title":"Postoperative Trichosporon asahii spondylodiscitis after open lumbar discectomy: a case report","volume":"33","author":"Kim","year":"2008","journal-title":"Spine"},{"key":"2023011810330052400_bib12","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/tid.12179","article-title":"Invasive Trichosporon infection in solid organ transplant patients: a report of two cases identified using IGS1 ribosomal DNA sequencing and a review of the literature","volume":"16","author":"Almeida J\u00fanior","year":"2014","journal-title":"Transpl Infect Dis"},{"key":"2023011810330052400_bib13","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1155\/2015\/458670","article-title":"Trichosporon asahii infection after total knee arthroplasty: a case report and review of the literature","volume":"26","author":"Zuo","year":"2015","journal-title":"Can J Infect Dis Med Microbiol"},{"key":"2023011810330052400_bib14","first-page":"24","article-title":"Periprosthetic fungal infection of a hip caused by Trichosporon inkin","volume-title":"Arthroplasty Today","author":"Burgo","year":"2018"},{"key":"2023011810330052400_bib15","doi-asserted-by":"crossref","first-page":"278","DOI":"10.4103\/1995-7645.284646","article-title":"Trichosporon asahii ankle cavity effusion infection in a patient with severe aplastic anemia","volume":"13","author":"Zhang","year":"2020","journal-title":"Asian Pac J Trop Med"},{"key":"2023011810330052400_bib16","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1017\/S0022215121000414","article-title":"Unusual complications of bone wax at the skull base","volume":"135","author":"Panicker","year":"2021","journal-title":"J Laryngol Otol"},{"key":"2023011810330052400_bib17","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1186\/s12879-021-06915-w","article-title":"Complicated Trichosporon asahii mastoiditis in immunocompetent child","volume":"21","author":"Al Momani","year":"2021","journal-title":"BMC Infect Dis"},{"key":"2023011810330052400_bib18","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.transproceed.2021.09.062","article-title":"Case report on sternal osteomyelitis by Trichosporon inkin complicating lung transplantation: effective treatment with vacuum-assisted closure and surgical reconstruction","volume":"54","author":"Ruiz","year":"2022","journal-title":"Transplant Proc"},{"key":"2023011810330052400_bib19","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/jpids\/piac064","article-title":"Multifocal Trichosporon asahii infection in a patient with chronic granulomatous disease","volume":"11","author":"Khalil","year":"2022","journal-title":"J Pediatric Infect Dis Soc"}],"container-title":["Medical Mycology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/mmy\/advance-article-pdf\/doi\/10.1093\/mmy\/myad001\/48500170\/myad001.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mmy\/article-pdf\/61\/1\/myad001\/48755896\/myad001.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mmy\/article-pdf\/61\/1\/myad001\/48755896\/myad001.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T10:33:15Z","timestamp":1674037995000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mmy\/article\/doi\/10.1093\/mmy\/myad001\/6969423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,29]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,12,29]]}},"URL":"https:\/\/doi.org\/10.1093\/mmy\/myad001","relation":{},"ISSN":["1369-3786","1460-2709"],"issn-type":[{"value":"1369-3786","type":"print"},{"value":"1460-2709","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,1]]},"published":{"date-parts":[[2022,12,29]]},"article-number":"myad001"}}