{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T01:01:04Z","timestamp":1776214864374,"version":"3.50.1"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"vor","delay-in-days":9,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","award":["2017\/50333-7"],"award-info":[{"award-number":["2017\/50333-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Military women on active duty are exposed to constant physical and mental demands, which may predispose them to some infection risks, including vulvovaginal candidiasis (VVC), a pathology considered a global public health problem. To monitor the prevalent and emerging pathogens in VVC, this study aimed to evaluate the distribution of yeast species and their in vitro antifungal susceptibility profile. We studied 104 vaginal yeast specimens obtained during routine clinical examinations. The population was attended at the Medical Center of the Military Police, S\u00e3o Paulo, Brazil, and was divided into two groups: infected patients (VVC) and colonised patients. Species were identified by phenotypic and proteomic methods (MALDI-TOF MS) and susceptibility to eight antifungal drugs, including azoles, polyenes, and echinocandins, was determined using microdilution broth. Candida albicans stricto sensu was found to be the most frequently isolated species (55%), but we observed a considerable rate of other Candida species isolates (30%), including Candida orthopsilosis stricto sensu only in the infected group. There were also other rare genera such as Rhodotorula, Yarrowia, and Trichosporon (15%), of which Rhodotorula mucilaginosa was the most prevalent in both groups. Fluconazole and voriconazole had the highest activity against all species in both groups. Candida parapsilosis was the most susceptible species, except for amphotericin-B in the infected group. Of note, we observed unusual resistance in C. albicans. Our results have allowed us to compile an epidemiological database on the etiology of VVC to support the empirical treatment and improve the health care of military women.<\/jats:p>","DOI":"10.1093\/mmy\/myad025","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T10:49:16Z","timestamp":1678358956000},"source":"Crossref","is-referenced-by-count":7,"title":["Species and antifungal susceptibility profile of agents causing vulvovaginal candidiasis in a military population: a cross-sectional study"],"prefix":"10.1093","volume":"61","author":[{"given":"D\u00e9bora Tha\u00eds Moreira","family":"Trajano","sequence":"first","affiliation":[{"name":"Postgraduate Program in Health Sciences, Institute of Medical Assistance to State Civil Servants of S\u00e3o Paulo (IAMSPE) , S\u00e3o Paulo ,","place":["Brazil"]},{"name":"Medical Center, Military Police of the State of S\u00e3o Paulo , S\u00e3o Paulo ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rcia de Souza Carvalho","family":"Melhem","sequence":"additional","affiliation":[{"name":"Mycology Unit, Adolfo Lutz Institute , Secretary of Health, S\u00e3o Paulo ,","place":["Brazil"]},{"name":"Graduate Program in Parasitic and Infectious Diseases, School of Medicine, Federal University of Mato Grosso do Sul , Campo Grande ,","place":["Brazil"]},{"name":"Graduate Program in Sciences, Coordination of Disease Control, Secretary of Health , S\u00e3o Paulo ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana Possatto Fernandes","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Mycology Unit, Adolfo Lutz Institute , Secretary of Health, S\u00e3o Paulo ,","place":["Brazil"]},{"name":"Graduate Program in Parasitic and Infectious Diseases, School of Medicine, Federal University of Mato Grosso do Sul , Campo Grande ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas Xavier","family":"Bonfietti","sequence":"additional","affiliation":[{"name":"Mycology Unit, Adolfo Lutz Institute , Secretary of Health, S\u00e3o Paulo ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam Rand\u00f3","family":"de Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Mycology Unit, Adolfo Lutz Institute , Secretary of Health, S\u00e3o Paulo ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviane Barbosa","family":"Corr\u00eaa","sequence":"additional","affiliation":[{"name":"Medical Center, Military Police of the State of S\u00e3o Paulo , S\u00e3o Paulo ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina Basseto de Oliveira","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Medical Center, Military Police of the State of S\u00e3o Paulo , S\u00e3o Paulo ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viviani","family":"Barnab\u00e9","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Health Sciences, Institute of Medical Assistance to State Civil Servants of S\u00e3o Paulo (IAMSPE) , S\u00e3o Paulo ,","place":["Brazil"]},{"name":"University of City of S\u00e3o Paulo , UNICID, S\u00e3o Paulo ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5828-3582","authenticated-orcid":false,"given":"Carolina Gon\u00e7alves","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Health Sciences, Institute of Medical Assistance to State Civil Servants of S\u00e3o Paulo (IAMSPE) , S\u00e3o Paulo ,","place":["Brazil"]},{"name":"Department of Physiological Sciences, Santa Casa of S\u00e3o Paulo School of Medical Sciences , S\u00e3o Paulo , 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