{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:34:06Z","timestamp":1793331246658,"version":"4.5.0"},"reference-count":109,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T00:00:00Z","timestamp":1703548800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Coccidioidomycosis is a potentially fatal fungal disease of humans and animals that follows inhalation of Coccidioides spp. arthroconidia in the environment. The disease in dogs resembles that in people, and because dogs may be at increased risk of exposure due to their proximity to the ground and digging behavior, they are valuable models for the disease in humans. Dogs have been sentinels for identification of new regions of endemicity in Washington and Texas. Canine serosurveillance has also been used to predict variables associated with environmental presence of Coccidioides spp. Expansion of the endemic region of coccidioidomycosis with climate change\u2014along with predicted population increases and increased development in the southwest United States\u2014may result in 45.4 million additional people at risk of infection by 2090. Here we provide an overview of the value of dogs as sentinels for the disease and encourage the routine reporting of coccidioidomycosis cases in dogs to public health agencies. We also highlight the value of dogs as naturally occurring models for studying novel treatment options and preventatives, such as a novel live avirulent coccidioidomycosis vaccine.<\/jats:p>","DOI":"10.1093\/mmy\/myad139","type":"journal-article","created":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T01:51:52Z","timestamp":1703641912000},"source":"Crossref","is-referenced-by-count":9,"title":["The dog as a sentinel and animal model for coccidioidomycosis"],"prefix":"10.1093","volume":"62","author":[{"given":"Adam J","family":"Ferguson","sequence":"first","affiliation":[{"name":"Department of Biological Sciences, University of California-San Diego , La Jolla , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8518-5750","authenticated-orcid":false,"given":"George R","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine \u2013 Division of Infectious Diseases, University of California-Davis , Davis , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bruyette","sequence":"additional","affiliation":[{"name":"Anivive Lifesciences , Long Beach , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6814-9835","authenticated-orcid":false,"given":"Jane E","family":"Sykes","sequence":"additional","affiliation":[{"name":"Department of Medicine & Epidemiology, University of California-Davis , Davis , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,12,26]]},"reference":[{"key":"2024011014310278400_bib1","year":"2022"},{"key":"2024011014310278400_bib2","article-title":"WHO fungal priority pathogens list to guide research, development and public health 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