{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:57:18Z","timestamp":1787497038120,"version":"build-2736575974"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T00:00:00Z","timestamp":1724976000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The skin of patients with atopic dermatitis (AD) has a greater diversity of mycobiota. An observational, prospective, cross-sectional, analytical, and comparative study was conducted involving 80 patients with AD Group (ADG) and 50 individuals without AD (wADG) in a tertiary hospital in Brazil. Skin scale samples were collected from the frontal, cervical, fossae cubital, and popliteal regions and identified using molecular biology techniques. The results showed that 47.5% of ADG had identified yeasts compared to 0% of wADG (P\u00a0&amp;lt;\u00a0.001). The yeasts Rhodotorula mucilaginosa and Candida parapsilosis were the most abundant. The probability of colonization increased with age, showing values of 40% at 60 months and 80% at 220 months (P\u00a0=\u00a0.09). The cervical region (12.5%) was colonized to the greatest extent. Our findings revealed that positive mycology was not more probable when the scoring of atopic dermatitis or eczema area and severity index value increased (P\u00a0=\u00a0.23 and .53, respectively). The results showed that the sex, age, and different population types directly affected the composition of the mycobiota in the population analyzed. A higher frequency of colonization and greater diversity of yeast species were detected in the cutaneous mycobiota of children with AD.<\/jats:p>","DOI":"10.1093\/mmy\/myae090","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T20:30:13Z","timestamp":1724963413000},"source":"Crossref","is-referenced-by-count":1,"title":["Molecular analysis of cutaneous yeast isolates in the mycobiota of children with atopic dermatitis"],"prefix":"10.1093","volume":"62","author":[{"given":"Iwyna Fran\u00e7a Souza Gomes","family":"Vial","sequence":"first","affiliation":[{"name":"Child and Adolescent Health Post-Graduation Program, Health Sciences Sector, Federal University of Parana , Curitiba, Paran\u00e1 80060-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgana Ferreira","family":"Voidaleski","sequence":"additional","affiliation":[{"name":"Microbiology, Parasitology and Pathology Post-Graduation Program, Department of Basic Pathology, Federal University of Parana , Curitiba, Paran\u00e1 81531-980 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ros\u00e2ngela Ferreira","family":"Lameira","sequence":"additional","affiliation":[{"name":"Clinical Analysis Laboratory Unit at Hospital de Cl\u00ednicas, Federal University of Parana , Curitiba, Paran\u00e1 80060-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia de Fatima","family":"Costa","sequence":"additional","affiliation":[{"name":"Engineering Bioprocess and Biotechnology Post-Graduation Program, Department of Bioprocess Engineering and Biotechnology, Federal University of Parana , Curitiba, Paran\u00e1 81530-000 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle Arake","family":"Zanatta","sequence":"additional","affiliation":[{"name":"Child and Adolescent Health Post-Graduation Program, Health Sciences Sector, Federal University of Parana , Curitiba, Paran\u00e1 80060-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vania Aparecida","family":"Vicente","sequence":"additional","affiliation":[{"name":"Microbiology, Parasitology and Pathology Post-Graduation Program, Department of Basic Pathology, Federal University of Parana , Curitiba, Paran\u00e1 81531-980 , Brazil"},{"name":"Child and Adolescent Health Post-Graduation Program, Health Sciences Sector, Federal University of Parana , Curitiba, Paran\u00e1 80060-900 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4578-8781","authenticated-orcid":false,"given":"Vania Oliveira","family":"de\u00a0Carvalho","sequence":"additional","affiliation":[{"name":"Child and Adolescent Health Post-Graduation Program, Health Sciences Sector, Federal University of Parana , Curitiba, Paran\u00e1 80060-900 , Brazil"},{"name":"Department of Pediatrics, Hospital de Cl\u00ednicas, Federal University of Parana , Curitiba, Paran\u00e1 81530-000 , Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,8,30]]},"reference":[{"key":"2024091413164331600_bib1","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000053860","article-title":"Atopic eczema\/dermatitis syndrome and Malassezia","volume":"127","author":"Scheynius","year":"2002","journal-title":"Int Arch Allergy Immunol"},{"key":"2024091413164331600_bib2","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1590\/S0365-05962010000200009","article-title":"Skin barrier in atopic dermatitis","volume":"85","author":"Addor","year":"2010","journal-title":"Ann Bras Dermatol"},{"key":"2024091413164331600_bib3","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/1744666X.2016.1212660","article-title":"Environmental risk factors and their role in the management of atopic dermatitis","volume":"13","author":"Kantor","year":"2017","journal-title":"Expert Rev Clin Immunol"},{"key":"2024091413164331600_bib4","doi-asserted-by":"crossref","first-page":"3","DOI":"10.3390\/toxins9010003","article-title":"The pathogenic effect of natural and bacterial toxins on atopic dermatitis","volume":"9","author":"Park","year":"2017","journal-title":"Toxins"},{"key":"2024091413164331600_bib5","first-page":"131","article-title":"Guia pr\u00e1tico de atualiza\u00e7\u00e3o em dermatite at\u00f3pica-Parte I: etiopatogenia, cl\u00ednica e diagn\u00f3stico. 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