{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:56:52Z","timestamp":1790812612830,"version":"4.1.0"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"vor","delay-in-days":4,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Genomics Research and Development Initiative"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Amphotericin B remains an important treatment for multidrug-resistant Candida auris. Antifungal susceptibility testing of amphotericin B in C. auris can vary depending on the methodology used. Here, we compared the Etest method and the Clinical and Laboratory Standards Institute broth microdilution reference method for amphotericin B against 60 clinical C. auris isolates from the four major clades. The minimum inhibitory concentrations differed significantly by method (P-value, &amp;lt;.0001), and discrepancies were observed in the interpretation of resistance (categorical agreement, 88.3%; very major error, 33.3%). Broth microdilution may represent a more conservative approach for detecting amphotericin B resistance in C. auris.<\/jats:p>","DOI":"10.1093\/mmy\/myaf019","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:25:06Z","timestamp":1741134306000},"source":"Crossref","is-referenced-by-count":5,"title":["Comparison of broth microdilution and Etest\u00ae methods for susceptibility testing of amphotericin B in <i>Candida auris<\/i>"],"prefix":"10.1093","volume":"63","author":[{"given":"Domenica G","family":"De\u00a0Luca","sequence":"first","affiliation":[{"name":"National Microbiology Laboratory Branch, Public Health Agency of Canada , Winnipeg, MB, R3E 3R2 ,","place":["Canada"]},{"name":"Department of Medical Microbiology and Infectious Diseases, University of Manitoba , Winnipeg, MB, R3E 0J9 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Rui","family":"Li","sequence":"additional","affiliation":[{"name":"National Microbiology Laboratory Branch, Public Health Agency of Canada , Winnipeg, MB, R3E 3R2 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C","family":"Alexander","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology and Infectious Diseases, University of Manitoba , Winnipeg, MB, R3E 0J9 ,","place":["Canada"]},{"name":"Cadham Provincial Laboratory, Diagnostic Services, Shared Health , Winnipeg, MB, R3E 3J7 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanis C","family":"Dingle","sequence":"additional","affiliation":[{"name":"Alberta Precision Laboratories \u2013 Public Health Laboratory , Calgary, AB, T2N 4W4 ,","place":["Canada"]},{"name":"Department of Pathology and Laboratory Medicine, University of Calgary , Calgary, AB, T2N 1N4 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe J","family":"Dufresne","sequence":"additional","affiliation":[{"name":"Laboratoire de sant\u00e9 publique du Qu\u00e9bec , Sainte-Anne-de-Bellevue, QC, H9X 3R5 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda M","family":"Hoang","sequence":"additional","affiliation":[{"name":"BC Centre for Diseases Control , Vancouver, BC, V5Z 4R4 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julianne V","family":"Kus","sequence":"additional","affiliation":[{"name":"Public Health Ontario , Toronto, ON, M5G 1M1 ,","place":["Canada"]},{"name":"Department of Laboratory Medicine and Pathobiology, University of Toronto , Toronto, ON, M5S 3K3 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Sheitoyan-Pesant","sequence":"additional","affiliation":[{"name":"Centre hospitalier universitaire Dr-Georges-L.-Dumont , Moncton, NB E1C 2Z3 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4171-9436","authenticated-orcid":false,"given":"Amrita","family":"Bharat","sequence":"additional","affiliation":[{"name":"National Microbiology Laboratory Branch, Public Health Agency of Canada , Winnipeg, MB, R3E 3R2 ,","place":["Canada"]},{"name":"Department of Medical Microbiology and Infectious Diseases, University of Manitoba , Winnipeg, MB, R3E 0J9 ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"2025031215215406900_bib1","volume-title":"WHO fungal priority pathogens list to guide research, development and public health action"},{"issue":"4","key":"2025031215215406900_bib2","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1093\/jac\/dkx480","article-title":"A multicentre study of antifungal 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