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Using bioinformatic methods, LysM proteins have been identified in representative yeasts of medical importance. However, LysM proteins have been found in only four ascomycete yeasts (Candida subhashii, C. tropicalis, Debaryomyces fabryi, and D. hansenii). In contrast, almost all basidiomycete yeasts contain at least one LysM effector but lack subgroup C chitinases. Notably, a unique LysM effector is highly conserved among all the lipid-dependent Malassezia species. The repertoire of LysM proteins in medically important yeasts appears to be more determined by the fungal lifestyle than by host colonization.<\/jats:p>","DOI":"10.1093\/mmy\/myaf118","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T13:01:55Z","timestamp":1765976515000},"source":"Crossref","is-referenced-by-count":0,"title":["Insights into LysM proteins of medically important yeasts"],"prefix":"10.1093","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3371-9981","authenticated-orcid":false,"given":"Jos\u00e9 A","family":"Oguiza","sequence":"first","affiliation":[{"name":"Genetics, Genomics and Microbiology Research Group, Institute for Multidisciplinary Research in Applied Biology (IMAB), Universidad P\u00fablica de Navarra (UPNA) , Campus de Arrosadia, 31006 Pamplona 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