{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T11:03:13Z","timestamp":1774004593142,"version":"3.50.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,2,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Reactivation of latent fungal infections poses a substantial risk for solid organ transplantation (SOT) and hematopoietic cell transplantation (HCT) recipients. We describe receipt of pretransplant fungal infection testing in an exploratory analysis among patients in a large US commercial health insurance database. We identified patients who received an SOT or HCT during January 1, 2018\u2013January 31, 2025, and evaluated testing practices for selected fungal (blastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis) and non-fungal infections (including hepatitis B virus [HBV], hepatitis C virus [HCV], HIV, cytomegalovirus [CMV], and tuberculosis) in the year before transplantation. In total, 8.9% of 11\u2009362 SOT and 13.0% of 6\u2009934 HCT recipients received pretransplant fungal testing. Among SOT recipients, Coccidioides antibody was the most frequent fungal test type (5.0%), with the highest rates in states with known endemicity (e.g., Arizona: 58.7%). Among HCT recipients, cryptococcal antigen testing was the most common fungal test type (5.2%). Testing rates for viral infections and tuberculosis were substantially higher compared with fungal infection testing: HBV (SOT: 65.1%, HCT: 73.4%), HCV (SOT: 55.8%, HCT: 71.1%), HIV (SOT: 45.5%, HCT: 66.3%), CMV (SOT: 41.7%, HCT: 65.9%), and tuberculosis (SOT: 38.0%, HCT: 16.8%). Pretransplant fungal infection testing was infrequently performed compared with recommended viral and tuberculosis screening, consistent with current guidelines. Further research to understand the clinical outcomes and cost-effectiveness associated with pretransplant fungal testing could help improve approaches for targeted screening.<\/jats:p>","DOI":"10.1093\/mmy\/myag018","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T12:37:13Z","timestamp":1771936633000},"source":"Crossref","is-referenced-by-count":0,"title":["Pretransplant serologic testing for fungal infections in a large commercial health insurance database, United States"],"prefix":"10.1093","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0458-2493","authenticated-orcid":false,"given":"Kaitlin","family":"Benedict","sequence":"first","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeremy A W","family":"Gold","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"Toda","sequence":"additional","affiliation":[{"name":"Mycotic Diseases Branch, Centers for Disease Control and Prevention , Atlanta, Georgia ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8093-5647","authenticated-orcid":false,"given":"Jessica S","family":"Little","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Brigham and Women\u2019s Hospital, Harvard Medical School , Boston, Massachusetts ,","place":["USA"]},{"name":"Stem Cell Transplant and Cellular Therapy, Dana-Farber Cancer Institute, Harvard Medical School , Boston, Massachusetts ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4784-7589","authenticated-orcid":false,"given":"Luis","family":"Ostrosky-Zeichner","sequence":"additional","affiliation":[{"name":"McGovern Medical School, University of Texas Health Science Center at Houston , Houston, Texas ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,2,24]]},"reference":[{"key":"2026032004512914500_bib1","doi-asserted-by":"publisher","first-page":"e70077","DOI":"10.1111\/tid.70077","article-title":"Invasive fungal disease in solid organ and hematopoietic cell transplant recipients, United States","volume":"27","author":"Gold","year":"2025","journal-title":"Transpl Infect Dis"},{"issue":"9","key":"2026032004512914500_bib2","doi-asserted-by":"publisher","first-page":"e13553","DOI":"10.1111\/ctr.13553","article-title":"Endemic fungal infections in solid organ transplant 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