{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T16:05:49Z","timestamp":1781625949243,"version":"3.54.5"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Candidozyma (formerly Candida) auris is a multidrug-resistant critical priority pathogen, posing significant challenges in high-risk settings. This study was aimed to determine the proportion of C. auris among candidemia, evaluate automated antifungal susceptibility testing (AFST) against Broth Microdilution (BMD), and identify high-risk areas in a haematology unit. A prospective cross-sectional study (September 2024\u2013September 2025) screened 3894 blood cultures in a Kolkata hospital. Isolates were identified via Vitek-2 and MALDI-TOF MS. Vitek 2 AFST results were compared with the gold-standard BMD. Spatial mapping was utilized to identify ward clustering. Excluding paediatric and non-haematology cases, the adult C. auris cohort (n\u00a0=\u00a038) was analysed (mean age 25.8\u00a0\u00b1\u00a011.2 years). All had haematological malignancy and neutropenia, with central venous catheters in 81.6% (n\u00a0=\u00a031). The 30-day crude mortality was 15.8% (n\u00a0=\u00a06). Diagnostically Vitek 2 demonstrated a critical 47.4% Major Error rate for Amphotericin B compared to BMD (P\u00a0&amp;lt; 0.001), significantly overestimating resistance. Spatial mapping identified persistent environmental reservoirs around specific high-traffic beds. Vitek 2 significantly overestimates Amphotericin B resistance, necessitating BMD verification to prevent inappropriate exclusion of polyene therapy. The infection burden in young, neutropenic adult highlights a vulnerable demographic. Persistence case clustering suggests environmental fomite colonization, requiring enhanced diagnostic stewardship and targeted sporicidal decontamination in haematology units.<\/jats:p>","DOI":"10.1093\/mmy\/myag055","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T11:47:32Z","timestamp":1780487252000},"source":"Crossref","is-referenced-by-count":0,"title":["High burden of multidrug-resistant\n                    <i>Candidozyma<\/i>\n                    (formerly\n                    <i>Candida) auris<\/i>\n                    in a tertiary care haematology unit: Diagnostic pitfalls and identification of high-risk clinical areas"],"prefix":"10.1093","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8861-7061","authenticated-orcid":false,"given":"Suman","family":"Kundu","sequence":"first","affiliation":[{"name":"ESI Hospital Sealdah Department of Microbiology, , Kolkata ,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3804-0422","authenticated-orcid":false,"given":"Chayanika","family":"Banerjee","sequence":"additional","affiliation":[{"name":"ECL Department of Microbiology, , Burdwan ,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5978-778X","authenticated-orcid":false,"given":"Swagata Ganguly","family":"Bhattacharjee","sequence":"additional","affiliation":[{"name":"Nil Ratan Sircar Medical College and Hospital Department of Microbiology, , Kolkata ,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"issue":"2","key":"2026061611114608200_bib1","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1093\/cid\/ciw691","article-title":"Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses","volume":"64","author":"Lockhart","year":"2017","journal-title":"Clin Infect Dis"},{"key":"2026061611114608200_bib2","volume-title":"Global Antimicrobial Resistance Surveillance System (GLASS): Early Implementation Protocol for Inclusion of Candida spp","author":"World Health Organization","year":"2019"},{"key":"2026061611114608200_bib3","article-title":"Candida auris","volume-title":"StatPearls","author":"Sikora","year":"2025"},{"issue":"3","key":"2026061611114608200_bib4","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/j.mycmed.2018.06.005","article-title":"Candida auris in critically ill patients: Emerging threat in intensive care unit of hospitals","volume":"28","author":"Das","year":"2018","journal-title":"Journal de Mycologie Medicale"},{"issue":"S1","key":"2026061611114608200_bib5","doi-asserted-by":"publisher","first-page":"s168","DOI":"10.1017\/ice.2020.694","article-title":"Clinical epidemiology and 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