{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T18:37:37Z","timestamp":1772995057546,"version":"3.50.1"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2018,6,19]],"date-time":"2018-06-19T00:00:00Z","timestamp":1529366400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,4,1]]},"DOI":"10.1093\/mmy\/myy044","type":"journal-article","created":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T03:12:41Z","timestamp":1526526761000},"page":"328-331","source":"Crossref","is-referenced-by-count":22,"title":["Antifungal activity of diphenyl diselenide alone and in combination with itraconazole against<i>Sporothrix brasiliensis<\/i>"],"prefix":"10.1093","volume":"57","author":[{"given":"Vanice Rodrigues","family":"Poester","sequence":"first","affiliation":[{"name":"Mycology Lab, Faculty of Medicine, Federal University of Rio Grande (FaMed-FURG), Rio Grande do Sul, Brazil"},{"name":"Post-graduation program in Health Science, FaMed-FURG, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonella Souza","family":"Mattei","sequence":"additional","affiliation":[{"name":"University of Caxias do Sul (UCS), RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josiara Furtado","family":"Mendes","sequence":"additional","affiliation":[{"name":"Mycology Lab, Faculty of Medicine, Federal University of Rio Grande (FaMed-FURG), Rio Grande do Sul, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel Baracy","family":"Klafke","sequence":"additional","affiliation":[{"name":"Mycology Lab, Faculty of Medicine, Federal University of Rio Grande (FaMed-FURG), Rio Grande do Sul, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivy Bastos","family":"Ramis","sequence":"additional","affiliation":[{"name":"Post-graduation program in Health Science, FaMed-FURG, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karine Ortiz","family":"Sanchotene","sequence":"additional","affiliation":[{"name":"Mycology Lab, Faculty of Medicine, Federal University of Rio Grande (FaMed-FURG), Rio Grande do Sul, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa Orzechowski","family":"Xavier","sequence":"additional","affiliation":[{"name":"Mycology Lab, Faculty of Medicine, Federal University of Rio Grande (FaMed-FURG), Rio Grande do Sul, Brazil"},{"name":"Post-graduation program in Health Science, FaMed-FURG, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2018,6,19]]},"reference":[{"key":"key\n\t\t\t\t2019030416255474800_bib1","doi-asserted-by":"crossref","first-page":"e2281","DOI":"10.1371\/journal.pntd.0002281","article-title":"Phylogenetic analysis reveals a high prevalence of Sporothrix brasiliensis in feline sporotrichosis outbreaks","volume":"7","author":"Rodrigues","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030416255474800_bib2","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1186\/s12917-014-0269-5","article-title":"Feline sporotrichosis due to Sporothrix brasiliensis: an emerging animal infection in S\u00e3o Paulo, Brazil","volume":"10","author":"Montenegro","year":"2014","journal-title":"BMC Vet Res"},{"key":"key\n\t\t\t\t2019030416255474800_bib3","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/myc.12414","article-title":"Sporothrix brasiliensis outbreaks and the rapid emergence of feline sporotrichosis","volume":"58","author":"Sanchotene","year":"2015","journal-title":"Mycoses"},{"key":"key\n\t\t\t\t2019030416255474800_bib4","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1111\/j.1469-0691.2009.02824.x","article-title":"Different virulence levels of the species of Sporothrix in a murine model","volume":"15","author":"Arrillaga-Moncrieff","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"key\n\t\t\t\t2019030416255474800_bib5","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1590\/0037-868215282013","article-title":"Atypical presentation of sporotrichosis: report of three cases","volume":"46","author":"Xavier","year":"2013","journal-title":"Rev Soc Bras Med Trop"},{"key":"key\n\t\t\t\t2019030416255474800_bib6","doi-asserted-by":"crossref","first-page":"e3094","DOI":"10.1371\/journal.pntd.0003094","article-title":"Sporotrichosis in Rio de Janeiro, Brazil: Sporothrix brasiliensis is associated with atypical clinical presentations","volume":"8","author":"Almeida-Paes","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030416255474800_bib7","first-page":"212308","article-title":"Phenotypic characteristics associated with virulence of clinical isolates from the Sporothrix complex","author":"Almeida-Paes","year":"2015","journal-title":"Biomed Res Int"},{"key":"key\n\t\t\t\t2019030416255474800_bib8","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/cid\/cir245","article-title":"Treatment of cutaneous sporotrichosis with itraconazole: study of 645 patients","volume":"52","author":"Barros","year":"2011","journal-title":"Clin Infect Dis"},{"key":"key\n\t\t\t\t2019030416255474800_bib9","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1751-0813.2011.00804.x","article-title":"Treatment of refractory feline sporotrichosis with a combination of intralesional amphotericin B and oral itraconazole","volume":"89","author":"Gremi\u00e3o","year":"2011","journal-title":"Aust Vet J"},{"key":"key\n\t\t\t\t2019030416255474800_bib10","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1136\/vr.166.10.290","article-title":"Response to azolic antifungal agents for treating feline sporotrichosis","volume":"166","author":"Pereira","year":"2010","journal-title":"Vet Rec"},{"key":"key\n\t\t\t\t2019030416255474800_bib11","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1093\/mmy\/myv120","article-title":"Antifugal activities of diphenyl diselenide and ebselen alone and in combination with antifungal agents against Fusarium spp","volume":"54","author":"Venturini","year":"2016","journal-title":"Med Mycol"},{"key":"key\n\t\t\t\t2019030416255474800_bib12","first-page":"8","article-title":"In vitro assessment of the growth and plasma membrane H + -ATPase inhibitory activity of ebselen and structurally related selenium- and sulfur-containing compounds in Candida albicans","volume":"2017","author":"Orie","journal-title":"J Biochem Mol Toxicol"},{"key":"key\n\t\t\t\t2019030416255474800_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cbi.2006.04.005","article-title":"Changes in biochemical parameters in rabbits blood after oral exposure to diphenyl diselenide for long periods","volume":"162","author":"De Bem","year":"2006","journal-title":"Chem Biol Interact"},{"key":"key\n\t\t\t\t2019030416255474800_bib14","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1742-7843.2007.00073.x","article-title":"Low toxicity of diphenyl diselenide in rabbits: a long-term study","volume":"101","author":"De Bem","year":"2007","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"key\n\t\t\t\t2019030416255474800_bib15","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1111\/j.1439-0507.2010.01994.x","article-title":"In vitro antifungal evaluation and structure\u2013activity relationship of diphenyl diselenide and synthetic analogues","volume":"54","author":"Loreto","year":"2010","journal-title":"Mycoses"},{"key":"key\n\t\t\t\t2019030416255474800_bib16","doi-asserted-by":"crossref","first-page":"e0004190","DOI":"10.1371\/journal.pntd.0004190","article-title":"Molecular diagnosis of pathogenic Sporothrix species","volume":"9","author":"Rodrigues","year":"2015","journal-title":"PLoS Negl Trop Dis"},{"key":"key\n\t\t\t\t2019030416255474800_bib17","first-page":"25","article-title":"Selenium reagents and intermediates in organic synthesis","volume-title":"Selenoorganic Functional Groups","author":"Paulmier","year":"1986","edition":"1st edn"},{"key":"key\n\t\t\t\t2019030416255474800_bib18","article-title":"Reference method for broth dilution antifungal susceptibility testing of filamentous fungi, approved standard, M38-A2","volume-title":"Clinical and Laboratory Standards Institute","author":"Clinical and Laboratory Standards Institute CLSI","year":"2008","edition":"2nd ed."},{"key":"key\n\t\t\t\t2019030416255474800_bib19","first-page":"432","article-title":"Antimicrobial combinations","volume-title":"Antibiotics in Laboratory Medicine","author":"Eliopoulos","edition":"3rd edn"},{"key":"key\n\t\t\t\t2019030416255474800_bib20","article-title":"Anti-Trichophyton activity of protocatechuates and their synergism with fluconazole","author":"Soares","year":"2014","journal-title":"Hindawi Publ Corp"},{"key":"key\n\t\t\t\t2019030416255474800_bib21","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.diagmicrobio.2016.08.002","article-title":"Synthesis, antifungal activity of caffeic acid derivative esters, and their synergism with fluconazole and nystatin against Candida spp","volume":"86","author":"Sardi","year":"2016","journal-title":"Diagn Microbiol Infect Dis"},{"key":"key\n\t\t\t\t2019030416255474800_bib22","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/j.1439-0507.2010.01888.x","article-title":"Candida albicans growth and germ tube formation can be inhibited by simple diphenyl diselenides [(PhSe)2 (MeOPhSe)2, (p-Cl-PhSe)2, (F3CPhSe)2] and diphenyl ditelluride","volume":"54","author":"Rosseti","year":"2010","journal-title":"Mycoses"},{"key":"key\n\t\t\t\t2019030416255474800_bib23","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.vetmic.2011.10.008","article-title":"Diphenyl diselenide in vitro and in vivo activity against the oomycete Pythium insidiosum","volume":"156","author":"Loreto","year":"2012","journal-title":"Vet Microbiol"},{"key":"key\n\t\t\t\t2019030416255474800_bib24","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s11046-013-9672-x","article-title":"Antifungal activities of diphenyl diselenide alone and in combination with fluconazole or amphotericin B against Candida glabrata","volume":"176","author":"Denardi","year":"2013","journal-title":"Mycopathologia"},{"key":"key\n\t\t\t\t2019030416255474800_bib25","first-page":"301","article-title":"Antifungal activities of diphenyl diselenide and ebselen against echinocandin-susceptible and -resistant strains of Candida parapsilosis","volume":"39","author":"Chassot","year":"2016","journal-title":"New Microbiol"},{"key":"key\n\t\t\t\t2019030416255474800_bib26","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s000110300001","article-title":"Anti-inflammatory and antinociceptive activity of diphenyl diselenide","volume":"52","author":"Nogueira","year":"2003","journal-title":"Inflamm Res"},{"key":"key\n\t\t\t\t2019030416255474800_bib27","doi-asserted-by":"crossref","first-page":"125","DOI":"10.18388\/abp.2009_2524","article-title":"Diphenyl diselenide and diphenyl ditelluride increase the latency for 4-aminopyridine-induced chemical seizure and prevent death in mice","volume":"56","author":"Brito","year":"2009","journal-title":"Acta Biochim Pol"},{"key":"key\n\t\t\t\t2019030416255474800_bib28","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1002\/cbf.1559","article-title":"Antioxidant effect of diphenyl diselenide on oxidative stress caused by acute physical exercise in skeletal muscle and lungs of mice","volume":"27","author":"Prigol","year":"2009","journal-title":"Cell Biochem Funct"},{"key":"key\n\t\t\t\t2019030416255474800_bib29","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.pathophys.2008.12.002","article-title":"Studies on preventive effects of diphenyl diselenide on acetaminophen-induced hepatotoxicity in rats","volume":"16","author":"Wilhelm","year":"2009","journal-title":"Pathophysiology"},{"key":"key\n\t\t\t\t2019030416255474800_bib30","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1021\/cr000426w","article-title":"Chemistry of Biologically Important Synthetic Organoselenium Compounds","volume":"101","author":"Mugesh","year":"2001","journal-title":"Chem Rev"},{"key":"key\n\t\t\t\t2019030416255474800_bib31","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1016\/j.lfs.2005.01.029","article-title":"Pro-oxidantaction of diphenyl diselenide in the yeast Saccharomyces cerevisiae exposed to ROS-generating conditions","volume":"77","author":"Rosa","year":"2005","journal-title":"Life Sci"},{"key":"key\n\t\t\t\t2019030416255474800_bib32","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1007\/s00284-010-9808-x","article-title":"Effects of glutathione modulation on oxidative stress and enzymatic antioxidant defence in yeast Pachysolen tannophilus","volume":"62","author":"Saharan","year":"2011","journal-title":"Curr Microbiol"},{"key":"key\n\t\t\t\t2019030416255474800_bib33","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.micres.2013.04.009","article-title":"2,2\u2032-Dithienyl diselenide pro-oxidant activity accounts for antibacterial and antifungal activities","volume":"168","author":"Pesarico","year":"2013","journal-title":"Microbiol Res"},{"key":"key\n\t\t\t\t2019030416255474800_bib34","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jtemb.2014.08.001","article-title":"Diphenyl diselenide (PhSe)2 inhibits biofilm formation by Candida albicans, increasing both ROS production and membrane permeability","volume":"29","author":"Rosseti","year":"2015","journal-title":"J Trace Elem Med Biol"},{"key":"key\n\t\t\t\t2019030416255474800_bib35","doi-asserted-by":"crossref","first-page":"3394","DOI":"10.1128\/AAC.46.11.3394-3400.2002","article-title":"Melanization of Cryptococcus neoformans and Histoplasma capsulatum reduces their susceptibilities to amphotericin B and caspofungin","volume":"46","author":"Van Duin","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"key\n\t\t\t\t2019030416255474800_bib36","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1348-0421.2003.tb03395.x","article-title":"Effects of melanin upon susceptibility of Cryptococcus to antifungals","volume":"47","author":"Ikeda","year":"2003","journal-title":"Microbiol Immunol"},{"key":"key\n\t\t\t\t2019030416255474800_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2180-6-55","article-title":"Effects of disrupting the polyketide synthase gene WdPKS1 in Wangiella [Exophiala] dermatitidis on melanin production and resistance to killing by antifungal compounds, enzymatic degradation, and extremes in temperature","volume":"6","author":"Paolo","year":"2006","journal-title":"BMC Microbiol"},{"key":"key\n\t\t\t\t2019030416255474800_bib38","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.riam.2015.03.001","article-title":"Interference of melanin in the susceptibility profile of Sporothrix species to amphotericin B","volume":"33","author":"Mario","year":"2015","journal-title":"Rev Iberoam Micol"},{"key":"key\n\t\t\t\t2019030416255474800_bib39","doi-asserted-by":"crossref","first-page":"e0152796","DOI":"10.1371\/journal.pone.0152796","article-title":"Melanins protect Sporothrix brasiliensis and Sporothrix schenckii from the antifungal effects of terbinafine","volume":"11","author":"Almeida-Paes","year":"2016","journal-title":"PLoS One"}],"container-title":["Medical Mycology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/mmy\/article-pdf\/57\/3\/328\/28010289\/myy044.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T04:15:23Z","timestamp":1571372123000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mmy\/article\/57\/3\/328\/5040117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,19]]},"references-count":39,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2018,6,19]]},"published-print":{"date-parts":[[2019,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/mmy\/myy044","relation":{},"ISSN":["1369-3786","1460-2709"],"issn-type":[{"value":"1369-3786","type":"print"},{"value":"1460-2709","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,4]]},"published":{"date-parts":[[2018,6,19]]}}}