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Yeast biofilms were evaluated by crystal violet staining, XTT reduction assay and microscopic techniques. Susceptibility of planktonic and sessile cells was analyzed by broth microdilution. S. schenckii complex in yeast form produced biofilms, with an optimum maturation at 96\u00a0h, showing multilayered blastoconidia embedded in extracellular matrix. KI and MIL minimum inhibitory concentration (MIC) ranges against planktonic cells were 62,500\u2013250,000\u00a0\u03bcg\/ml and 0.125\u20134\u00a0\u03bcg\/ml, respectively. KI and MIL reduced biofilm metabolic activity by 75.4% and 67.7% for filamentous form and 55.1% and 51.6% for yeast form, respectively. This study demonstrated that S. schenckii complex forms biofilms in vitro, and potassium iodide and miltefosine inhibit Sporothrix spp. biofilms in both filamentous and yeast forms.<\/jats:p>","DOI":"10.1093\/mmy\/myy119","type":"journal-article","created":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T19:26:36Z","timestamp":1540236396000},"page":"764-772","source":"Crossref","is-referenced-by-count":31,"title":["Potassium iodide and miltefosine inhibit biofilms of Sporothrix schenckii species complex in yeast and filamentous forms"],"prefix":"10.1093","volume":"57","author":[{"given":"Raimunda S\u00e2mia Nogueira","family":"Brilhante","sequence":"first","affiliation":[{"name":"Specialized Medical Mycology Center, Postgraduate Program in Medical Microbiology, Department of Pathology and Legal Medicine, Federal University of Cear\u00e1, Fortaleza, CE, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Lucilene Queiroz 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