{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T06:14:04Z","timestamp":1788502444834,"version":"build-2803163510"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Candida auris is an emergent yeast pathogen, easily transmissible between patients and with high percent of multidrug resistant strains. Here we present a draft genome sequence of the first known Russian strain of C.\u00a0auris, isolated from a case of candidemia. The strain clustered within South Asian C.\u00a0auris clade and seemingly represented an independent event of dissemination from the original species range. Observed fluconazole resistance was probably due to F105L and K143R mutations in ERG11.<\/jats:p>","DOI":"10.1093\/mmy\/myz078","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T11:09:42Z","timestamp":1560856182000},"page":"414-416","source":"Crossref","is-referenced-by-count":18,"title":["Whole genome sequence of first Candida auris strain, isolated in Russia"],"prefix":"10.1093","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3062-3316","authenticated-orcid":false,"given":"Ivan M","family":"Pchelin","sequence":"first","affiliation":[{"name":"Kashkin Research Institute of Medical Mycology, North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia"},{"name":"Department of Medical Microbiology, North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2483-5144","authenticated-orcid":false,"given":"Daniil V","family":"Azarov","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Parasitology and Disinfectology, North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria A","family":"Churina","sequence":"first","affiliation":[{"name":"City Hospital No. 40, Saint Petersburg, Russia"},{"name":"Clinical Infectious Diseases Hospital named after S.P. Botkin, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor A","family":"Ryabinin","sequence":"first","affiliation":[{"name":"Kashkin Research Institute of Medical Mycology, North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irina V","family":"Vibornova","sequence":"first","affiliation":[{"name":"Kashkin Research Institute of Medical Mycology, North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3853-4185","authenticated-orcid":false,"given":"Svetlana V","family":"Apalko","sequence":"first","affiliation":[{"name":"City Hospital No. 40, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander N","family":"Kruglov","sequence":"first","affiliation":[{"name":"National Agency for Clinical Pharmacology and Pharmacy, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3198-8990","authenticated-orcid":false,"given":"Andrey M","family":"Sarana","sequence":"first","affiliation":[{"name":"Medical Faculty, Saint Petersburg State University, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1725-8433","authenticated-orcid":false,"given":"Anastasia E","family":"Taraskina","sequence":"first","affiliation":[{"name":"Kashkin Research Institute of Medical Mycology, North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3693-5468","authenticated-orcid":false,"given":"Natalya V","family":"Vasilyeva","sequence":"first","affiliation":[{"name":"Kashkin Research Institute of Medical Mycology, North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia"},{"name":"Department of Medical Microbiology, North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,7,9]]},"reference":[{"key":"2020042809355812500_bib1","doi-asserted-by":"crossref","first-page":"pii: e00029\u201317","DOI":"10.1128\/CMR.00029-17","article-title":"Candida auris: a review of the literature","volume":"31","author":"Jeffery-Smith","year":"2017","journal-title":"Clin Microbiol Rev"},{"key":"2020042809355812500_bib2","first-page":"w14622","article-title":"First case of Candida auris in Switzerland: discussion about preventive strategies","volume":"148","author":"Riat","year":"2018","journal-title":"Swiss Med Wkly"},{"key":"2020042809355812500_bib3","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1348-0421.2008.00083.x","article-title":"Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital","volume":"53","author":"Satoh","year":"2009","journal-title":"Microbiol Immunol"},{"key":"2020042809355812500_bib4","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s40560-018-0342-4","article-title":"Epidemiology, clinical characteristics, resistance, and treatment of infections by Candida auris","volume":"6","author":"Cortegiani","year":"2018","journal-title":"J Intensive Care"},{"key":"2020042809355812500_bib5","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1093\/cid\/ciw691","article-title":"Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses","volume":"64","author":"Lockhart","year":"2017","journal-title":"Clin Infect Dis"},{"key":"2020042809355812500_bib6","article-title":"The first Russian case of candidaemia due to Candida auris","volume-title":"28th European Conference of Clinical Microbiology and Infectious Diseases (ECCMID), Madrid, Spain 21\u201324","author":"Vasilyeva","year":"2018"},{"key":"2020042809355812500_bib7","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/myc.12505","article-title":"Reconstruction of phylogenetic relationships in dermatomycete genus Trichophyton Malmsten 1848 based on ribosomal internal transcribed spacer region, partial 28S rRNA and beta-tubulin genes sequences","volume":"59","author":"Pchelin","year":"2016","journal-title":"Mycoses"},{"key":"2020042809355812500_bib8","article-title":"Species boundaries in the Trichophyton mentagrophytes \/ T. interdigitale species complex","author":"Pchelin","year":"2018  21","journal-title":"Med Mycol"},{"key":"2020042809355812500_bib9","article-title":"FastQC: a quality control tool for high throughput sequence data","author":"Andrews","year":"2010"},{"key":"2020042809355812500_bib10","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"2020042809355812500_bib11","first-page":"158","article-title":"Assembling genomes and minimetagenomes from highly chimeric reads","volume-title":"Research in Computational Molecular Biology. RECOMB 2013. Lecture Notes in Computer Science","author":"Nurk"},{"key":"2020042809355812500_bib12","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1093\/bioinformatics\/btt086","article-title":"QUAST: quality assessment tool for genome assemblies","volume":"29","author":"Gurevich","year":"2013","journal-title":"Bioinformatics"},{"key":"2020042809355812500_bib13","doi-asserted-by":"crossref","first-page":"e87991","DOI":"10.1371\/journal.pone.0087991","article-title":"Evaluation of whole genome sequencing for outbreak detection of Salmonella enterica","volume":"9","author":"Leekitcharoenphon","year":"2014","journal-title":"PLoS One"},{"key":"2020042809355812500_bib14","doi-asserted-by":"crossref","first-page":"e00722","DOI":"10.1128\/genomeA.00722-15","article-title":"Draft genome sequence of a fluconazole-resistant Candida auris strain from a candidemia patient in India","volume":"3","author":"Sharma","year":"2015","journal-title":"Genome Announc"},{"key":"2020042809355812500_bib15","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1016\/S1473-3099(18)30597-8","article-title":"Multiple introductions and subsequent transmission of multidrug-resistant Candida auris in the USA: a molecular epidemiological survey","volume":"18","author":"Chow","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"2020042809355812500_bib16","first-page":"43","article-title":"Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris","volume":"7","author":"Rhodes","year":"2018","journal-title":"Emerg Microbes Infect"},{"key":"2020042809355812500_bib17","first-page":"pii: S0195-6701(19)30104-5","article-title":"Emergence of Candida auris in Russia","author":"Barantsevich","year":"2019","journal-title":"J Hosp Infect"},{"key":"2020042809355812500_bib18","doi-asserted-by":"crossref","first-page":"5346","DOI":"10.1038\/s41467-018-07779-6","article-title":"Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species","volume":"9","author":"Mu\u00f1oz","year":"2018","journal-title":"Nat Commun"},{"key":"2020042809355812500_bib19","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.ijantimicag.2017.05.012","article-title":"Molecular basis of antifungal drug resistance in yeasts","volume":"50","author":"Morio","year":"2017","journal-title":"Int J Antimicrob Agents"}],"container-title":["Medical Mycology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/mmy\/article-pdf\/58\/3\/414\/33138109\/myz078.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/mmy\/article-pdf\/58\/3\/414\/33138109\/myz078.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T13:41:43Z","timestamp":1588081303000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mmy\/article\/58\/3\/414\/5530410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,9]]},"references-count":19,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,7,9]]},"published-print":{"date-parts":[[2020,4,1]]}},"URL":"https:\/\/doi.org\/10.1093\/mmy\/myz078","relation":{},"ISSN":["1369-3786","1460-2709"],"issn-type":[{"value":"1369-3786","type":"print"},{"value":"1460-2709","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,4]]},"published":{"date-parts":[[2019,7,9]]}}}