{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T17:58:10Z","timestamp":1772819890733,"version":"3.50.1"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2019,11,16]],"date-time":"2019-11-16T00:00:00Z","timestamp":1573862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Blastomycosis is a systemic fungal infection that most commonly affects dogs and humans. The disease is thought to be endemic in southern regions of Michigan, USA, but epidemiologic investigations have not been reported in detail for this state. The primary aims of this study were to investigate the prevalence and distribution of canine blastomycosis cases in Michigan and to identify risk factors for infection. Over 200 primary care veterinary clinics throughout the state were surveyed regarding blastomycosis prevalence, and demographic information was obtained from medical records of affected dogs that were evaluated at these clinics. A retrospective case control study was conducted for an additional 49 dogs with blastomycosis that were evaluated at specialty referral centers located in the southern mid-Michigan region. Prevalence rates were calculated for each county, and cases were mapped using geocoding software. Univariable and multivariable analyses were used to identify risk factors for infection. Prevalence rates were\u00a0\u2265100 cases per 100,000 dogs in five counties. Most blastomycosis cases originated from the Upper Peninsula or from a high-density area in the northern Lower Peninsula. Multivariable regression analysis identified travel or residence north of the 45th parallel as a strong risk factor for infection (P\u00a0&amp;lt;\u00a0.001). Blastomycosis was uncommon in southern counties. These results refute previous speculations and should be of value to both human and animal health. Given that many heightened risk areas are popular tourist destinations, practitioners across the USA should be mindful of the spatial distribution of blastomycosis in Michigan.<\/jats:p>","DOI":"10.1093\/mmy\/myz110","type":"journal-article","created":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T19:10:02Z","timestamp":1571425802000},"page":"609-616","source":"Crossref","is-referenced-by-count":11,"title":["Prevalence, distribution, and risk factors for canine blastomycosis in Michigan, USA"],"prefix":"10.1093","volume":"58","author":[{"given":"Leslie M","family":"Shelnutt","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences, Michigan State University College of Veterinary Medicine, East Lansing, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B","family":"Kaneene","sequence":"first","affiliation":[{"name":"Center for Comparative Epidemiology, Michigan State University College of Veterinary Medicine, East Lansing, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo A M","family":"Carneiro","sequence":"first","affiliation":[{"name":"Center for Comparative Epidemiology, Michigan State University College of Veterinary Medicine, East Lansing, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7726-6307","authenticated-orcid":false,"given":"Daniel K","family":"Langlois","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences, Michigan State University College of Veterinary Medicine, East Lansing, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,11,16]]},"reference":[{"key":"2020063020041444800_bib1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.idc.2015.10.002","article-title":"Blastomycosis","volume":"30","author":"Castillo","year":"2016","journal-title":"Infect Dis Clin 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