{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:29:27Z","timestamp":1787070567980,"version":"build-2736575974"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":35,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009745","name":"Emil and Wera Cornell Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009745","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tore Nilson Foundation"},{"name":"Erik & Lily Philipsons foundation"},{"name":"Swedish government and the country councils","award":["ALFGBG-720851"],"award-info":[{"award-number":["ALFGBG-720851"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Here, we developed and validated a high throughput proteomics workflow that enables combined profiling of global proteomes and post-translational modifications (PTMs) without conventional enrichment or fractionation. Using mass spectrometry-based methods, we identified PTM landscapes, particularly N-glycopeptides and non-enzymatic glycated peptides, from the same sample prepared for global proteomics. Applying this methodology to investigate longitudinal serum in women at 6 and 10\u00a0years post-gestational diabetes mellitus (GDM), we identified PTM signatures, including N-glycosylation and non-enzymatic glycation, associated with development of type 2 diabetes (T2D) and prediabetes, which were confirmed in an independent T2D cohort.<\/jats:p>","DOI":"10.1093\/molecular-omics\/aaiag020","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T15:37:53Z","timestamp":1785944273000},"source":"Crossref","is-referenced-by-count":0,"title":["Rapid serum proteome profiling of glycation and N-glycosylation in women with a history of gestational diabetes"],"prefix":"10.1093","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8959-165X","authenticated-orcid":false,"given":"Philip","family":"To","sequence":"first","affiliation":[{"name":"Dynamic Omics, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca , 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