{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:09:10Z","timestamp":1777860550278,"version":"3.51.4"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,9,4]],"date-time":"2021-09-04T00:00:00Z","timestamp":1630713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,28]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The aim of this study is to investigate the outcomes of coronavirus disease 2019 (COVID-19) in our cohort of Beh\u00e7et\u2019s disease (BD) patients and to reveal the rate of BD exacerbations due to COVID-19.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Patients who have been followed with a diagnosis of BD were retrospectively investigated for a positive severe acute respiratory syndrome\u2013coronavirus 2 polymerized chain reaction (PCR) test. Data regarding demographics, clinical features and COVID-19 outcomes were collected from medical records for patients with a positive PCR. PCR-positive patients were reached via phone numbers, and \u2018Beh\u00e7et\u2019s Disease Current Activity Form\u2019 (BDCAF) scores for pre- and post-COVID-19 BD symptoms were calculated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Out of a total 648 BD patients, 59 were detected to have a positive PCR test. Three of the 59 patients (5.0%) were found to be hospitalized, none of them was admitted to the ICU or died. An increasing trend in the frequency of comorbid diseases and older age was observed in hospitalized patients. 32.2% of BD patients suffered from exacerbation of at least one symptom related to BD.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We observed no ICU admission or mortality with COVID-19 in our BD patient cohort. A substantial number of patients suffered from exacerbation of BD symptoms.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roab016","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T11:22:00Z","timestamp":1634728920000},"page":"455-459","source":"Crossref","is-referenced-by-count":11,"title":["COVID-19 in patients with Beh\u00e7et\u2019s disease: Outcomes and rate of Beh\u00e7et\u2019s exacerbations in a retrospective cohort"],"prefix":"10.1093","volume":"32","author":[{"given":"B\u00fcnyamin","family":"Polat","sequence":"first","affiliation":[{"name":"Clinic of Rheumatology, Ministry of Health Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulsamet","family":"Erden","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Ministry of Health Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1965-9756","authenticated-orcid":false,"given":"Serdar Can","family":"G\u00fcven","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Ministry of Health Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berkan","family":"Arma\u011fan","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Ministry of Health Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem","family":"Karaka\u015f","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Ministry of Health Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bahar","family":"\u00d6zdemir","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Ministry of Health Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Apayd\u0131n","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Ministry of Health Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eren","family":"Usul","sequence":"additional","affiliation":[{"name":"Clinic of Emergency Medicine, Sincan Dr Nafiz K\u00f6rez State Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130hsan","family":"Ate\u015f","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Health Sciences, Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orhan","family":"K\u00fc\u00e7\u00fck\u015fahin","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Rheumatology, School of Medicine, Y\u0131ld\u0131r\u0131m Beyaz\u0131t University, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Omma","sequence":"additional","affiliation":[{"name":"Clinic of Rheumatology, Ministry of Health Ankara City Hospital, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,9,4]]},"reference":[{"key":"2022030816021575800_R1","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(20)30566-3","article-title":"Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study","volume":"395","author":"Zhou","year":"2020","journal-title":"Lancet"},{"key":"2022030816021575800_R2","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1056\/NEJMcp2009249","article-title":"Mild or moderate Covid-19","volume":"383","author":"Gandhi","year":"2020","journal-title":"N Engl J Med"},{"key":"2022030816021575800_R3","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.thromres.2020.04.041","article-title":"Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: an updated analysis","volume":"191","author":"Klok","year":"2020","journal-title":"Thromb Res"},{"key":"2022030816021575800_R4","article-title":"COVID-19 and Beh\u00e7et\u2019s disease: clinical case series","author":"Espinosa","year":"2020","journal-title":"Ann Rheum Dis"},{"key":"2022030816021575800_R5","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1007\/s11739-020-02427-8","article-title":"Characteristics and outcomes of Beh\u00e7et\u2019s syndrome patients with coronavirus disease 2019: a case series of 10 patients","volume":"15","author":"Yurtta\u015f","year":"2020","journal-title":"Intern Emerg Med"},{"key":"2022030816021575800_R6","first-page":"1078","article-title":"Criteria for diagnosis of Beh\u00e7et\u2019s disease. 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