{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:42:06Z","timestamp":1740109326170,"version":"3.37.3"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,9,3]],"date-time":"2021-09-03T00:00:00Z","timestamp":1630627200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,20]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Vogt\u2013Koyanagi\u2013Harada Disease (VKHD) is a systemic autoimmune disorder characterized by granulomatous panuveitis. Inflammatory rheumatic diseases (IRDs) are among the differential diagnosis of VKHD. However, current knowledge on the rheumatological aspects of VKHD is still limited. We aimed to investigate the prevalence of rheumatic conditions in VKHD patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>VKHD patients were included in the study and they were reviewed in terms of the presence of any rheumatological manifestations.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were 18 patients with a female preponderance (83.3%, female). Inflammatory type of peripheral joint pain (11%) and sicca symptoms (33%) were the most common rheumatological findings. The frequency of spondyloarthritis-related features such as inflammatory back pain and HLA-B27 rate was not increased. None of the patients had radiographic sacroiliitis. Anti-nuclear antibody was positive in high titres nearly in 30% of the patients and three patients had antibodies against extractable nuclear antigens. Nailfold capillaroscopy was abnormal in about one-third of the patients. Pathergy test was negative in all cohorts. While angiotensin-converting enzyme was elevated in nearly 20% of the patients, there were no abnormalities on chest X-rays.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>VKHD shares some features with IRDs. The common features were mostly suggestive of connective tissue disease rather than SpA or rheumatoid arthritis.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roab061","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T00:57:16Z","timestamp":1633913836000},"page":"994-998","source":"Crossref","is-referenced-by-count":0,"title":["Rheumatologic manifestations in a cohort of patients with Vogt\u2013Koyanagi\u2013Harada disease"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5481-0776","authenticated-orcid":false,"given":"Sinem Burcu","family":"Kocaer","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Dokuz Eylul University , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmut","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dokuz Eylul University , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzan Guven","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Ege University , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziya","family":"Ayhan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dokuz Eylul University , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Osman","family":"Saatci","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dokuz Eylul University , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatos","family":"Onen","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Dokuz Eylul University , Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail","family":"Sari","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Dokuz 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