{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:32:05Z","timestamp":1780050725936,"version":"3.53.1"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2021,10,16]],"date-time":"2021-10-16T00:00:00Z","timestamp":1634342400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,20]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To clarify the ultrasonographic features of immunoglobulin G4 (IgG4)-related dacryoadenitis and sialadenitis (IgG4-DS) and their usefulness in clinical diagnostic sessions.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>By re-evaluating 96 consecutive patients with IgG4-related disease, we identified 54 patients (male:female\u2009=\u200937:17; median age, 69.5\u2009years) who underwent lacrimal or submandibular gland (LG or SG, respectively) ultrasonography and computed tomography (CT). Their clinical and ultrasonographic features were retrospectively analysed. Radio-pathological correlations were also examined in LG (23 cases) and SG lesions (20 cases). Additionally, the diagnostic accuracy of CT for LG\/SG lesions was evaluated.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Abnormal ultrasonographic findings were detected in 33 (LGs) and 38 (SGs) patients, and most of them were observed bilaterally. All lesions were well demarcated and demonstrated diffuse low-echoic areas (rocky pattern) or multiple low-echoic nodules surrounded by high-echoic linear shadows (cobblestone pattern) corresponding to intra-lobular inflammation and inter-lobular fibrosis. Moreover, 42% (LGs; 14\/33) and 42% (SGs; 16\/38) patients had glandular lesions without clinical symptoms associated with the affected glands. The diagnostic accuracy of CT was \u223c80% for LG and 55% for SG.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Ultrasonographic findings in IgG4-DS included diffuse or nodular low-echoic areas with linear high-echoic structures corresponding to inflamed lobules and inter-lobular fibrosis. These findings can help detect IgG4-DS.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roab063","type":"journal-article","created":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T18:36:36Z","timestamp":1634754996000},"page":"986-993","source":"Crossref","is-referenced-by-count":10,"title":["Ultrasonography of IgG4-related dacryoadenitis and sialadenitis: Imaging features and clinical usefulness"],"prefix":"10.1093","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1900-5042","authenticated-orcid":false,"given":"Takahiro","family":"Komori","sequence":"first","affiliation":[{"name":"Department of Radiology, Kanazawa University Graduate School of Medical Science , Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dai","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kanazawa University Graduate School of Medical Science , Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Izumozaki","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kanazawa University Graduate School of Medical Science , Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Sugiura","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kanazawa University Graduate School of Medical Science , Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanako","family":"Terada","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kanazawa University Graduate School of Medical Science , Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norihide","family":"Yoneda","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kanazawa University Graduate School of Medical Science , Kanazawa, 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Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Takahira","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kanazawa University Graduate School of Medical Science , Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhiro","family":"Kawano","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Internal Medicine, Kanazawa University Graduate School of Medical Science , Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Kanazawa University Graduate School of Medical Science , Kanazawa, Japan"},{"name":"Department of Quantum Medical Imaging, Kanazawa University Graduate School of Medical Sciences , Kanazawa, 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