{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:41:56Z","timestamp":1740109316244,"version":"3.37.3"},"reference-count":24,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2022,2,3]],"date-time":"2022-02-03T00:00:00Z","timestamp":1643846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,1,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>This study clarifies the involvement of gender and pre-existing diabetes mellitus (DM) in the clinical characteristics of polymyalgia rheumatica (PMR).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The clinical records of patients diagnosed with PMR in our department between January 2011 and June 2021, especially in terms of gender and DM were retrospectively analysed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We identified 89 patients with the median age of 75.37 cases were men and 52 cases were women. Pre-existing DM was found in 21 patients (23.6%). Male PMR patients exhibited a higher complication rate of pre-existing DM and C-reactive protein (CRP) levels at diagnosis (p\u2009=\u2009.04 and p\u2009&amp;lt;\u2009.01, respectively) than female patients, and men were more common in the patient group with pre-existing DM (p\u2009=\u2009.04). The CRP levels of male PMR patients without pre-existing DM were higher than female PMR patients without pre-existing DM.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Male PMR patients might have a varying pathophysiology from female patients in terms of high inflammation levels accompanied by a high prevalence rate of pre-existing DM and need a gender-specific approach.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roac012","type":"journal-article","created":{"date-parts":[[2022,2,8]],"date-time":"2022-02-08T22:12:35Z","timestamp":1644358355000},"page":"182-186","source":"Crossref","is-referenced-by-count":2,"title":["Clinical analysis of gender and pre-existing diabetes mellitus in patients with polymyalgia rheumatica: A retrospective study in a Japanese population"],"prefix":"10.1093","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2366-3566","authenticated-orcid":false,"given":"Yoshiro","family":"Horai","sequence":"first","affiliation":[{"name":"Department of Rheumatology, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"},{"name":"Clinical Research Center, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mizuna","family":"Otsuka","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chieko","family":"Kawahara","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nozomi","family":"Iwanaga","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Yamasaki","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taro","family":"Watanobe","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Yasui","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Saishoji","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Torisu","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takahiro","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasumori","family":"Izumi","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center , Omura, Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Kawakami","sequence":"additional","affiliation":[{"name":"Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences , Nagasaki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,2,3]]},"reference":[{"key":"2023011210570302300_R1","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1136\/annrheumdis-2011-200329","article-title":"2012 provisional classification criteria for polymyalgia rheumatica: 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