{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:42:17Z","timestamp":1740109337747,"version":"3.37.3"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,13]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The purpose of this study was to evaluate the new incidence of carotid plaques in rheumatoid arthritis (RA) patients over a 6-year prospective follow-up and to assess the risk factors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>This is a 10-year prospective cohort study that included 208 RA patients and 205 age- and gender-matched controls. Ultrasound assessment of the bilateral carotid arteries was performed in 2011 and 2017.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were no differences in the incidence of new carotid atherosclerotic plaques over 6\u2009years between the two groups (35.5% vs. 37.0%, respectively; p\u2009=\u2009.936). The mean Disease Activity Score 28-C-reactive protein over 6\u2009years in RA patients was 2.73\u2009\u00b1\u20090.95. Multiple logistic regression analysis showed that RA was not a risk factor for new carotid atherosclerotic plaques (odds ratios, 0.708; 95% confidence interval, 0.348\u20131.440; p\u2009=\u2009.340). An average glucocorticoid dose of &amp;gt;1.8\u2009mg\/day over 6\u2009years was a risk factor for new carotid atherosclerotic plaques (odds ratios, 8.54; 95% confidence interval, 1.641\u201344.455; p\u2009=\u2009.011).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Incidence of new carotid atherosclerotic plaques was similar between well-controlled disease activity RA patients and control subjects. A mean glucocorticoid dose of &amp;gt;1.8\u2009mg\/day over 6\u2009years was a risk factor for new carotid atherosclerotic plaques.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roac051","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T11:23:59Z","timestamp":1654169039000},"page":"481-489","source":"Crossref","is-referenced-by-count":0,"title":["Incidence of new carotid plaques in rheumatoid arthritis patients: 6-Year prospective results of the TOMORROW study"],"prefix":"10.1093","volume":"33","author":[{"given":"Shohei","family":"Anno","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Osaka Metropolitan University Graduate School of Medicine , Osaka, Japan"},{"name":"Department of Orthopaedic Surgery, Yodogawa Christian Hospital , Osaka, 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Orthopaedic Surgery, Osaka City General Hospital , Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Inui","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Osaka Metropolitan University Graduate School of Medicine , Osaka, Japan"},{"name":"Department of Orthopaedic Surgery, Osaka Saiseikai Nakatsu Hospital , Osaka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Koike","sequence":"additional","affiliation":[{"name":"Center for Senile Degenerative Disorders (CSDD), Osaka Metropolitan University Graduate School of Medicine , Osaka, Japan"},{"name":"Search Institute for Bone and Arthritis Disease (SINBAD), Shirahama Foundation for Health and Welfare , Wakayama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Osaka Metropolitan 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