{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T10:33:29Z","timestamp":1787654009353,"version":"build-2736575974"},"reference-count":37,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,13]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The purpose of the present study was to evaluate improvement in the Knee Injury and Osteoarthritis Outcome Score (KOOS) after open-wedge high tibial osteotomy (HTO) in comparison with total knee arthroplasty (TKA) in cohorts over age 60 matched by pre-operative age, gender, body mass index (BMI), hip-knee-ankle angle (HKAA), KOOS sub-scores, and osteoarthritis (OA) grade.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Propensity score matching was performed between 162 HTO patients and 134 TKA patients. When calculating the propensity score by multivariate logistic regression analysis, the following pre-operative confounders were included: age, gender, BMI, HKAA, KOOS sub-scores, and OA grade. Consequently, a total of 55 patients were included in each group. The Student\u2019s t-test was used to analyse differences in the post-operative KOOS sub-scores between groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>After propensity score matching, all matched pre-operative valuables were identical, with no significant differences between the HTO and TKA groups. None of the post-operative KOOS sub-scores at 1\u2009year after surgery showed a significant difference between the HTO and TKA groups. Both groups demonstrated significant and comparable post-operative improvement in every KOOS sub-score.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>In patients over age 60, there was no significant difference in short-term pain relief and improvements in activity and quality of life between HTO and TKA after propensity score matching including pre-operative age, KOOS sub-scores, and OA grade. HTO is a joint preservation procedure that is valid for knee OA even in individuals over age 60.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roac052","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T12:34:10Z","timestamp":1654173250000},"page":"623-628","source":"Crossref","is-referenced-by-count":7,"title":["Similar short-term KOOS between open-wedge high tibial osteotomy and total knee arthroplasty in patients over age 60: A propensity score\u2013matched cohort study"],"prefix":"10.1093","volume":"33","author":[{"given":"Mamiko","family":"Sakai","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyushu University , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3666-3952","authenticated-orcid":false,"given":"Yukio","family":"Akasaki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyushu University , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takenori","family":"Akiyama","sequence":"additional","affiliation":[{"name":"Akiyama Clinic , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Horikawa","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Omuta Tenryo Hospital , Omuta, Japan"},{"name":"Department of Orthopaedic Surgery, National Hospital Organization Kumamoto Saishun Medical Center , Koshi, Kumamoto, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Okazaki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Tokyo Women\u2019s Medical University , Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Hamai","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyushu University , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetoshi","family":"Tsushima","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyushu University , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinya","family":"Kawahara","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyushu University , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Kurakazu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyushu University , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Kubota","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Omuta Tenryo Hospital , Omuta, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Mizu-uchi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Saiseikai Fukuoka General Hospital , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuharu","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Kyushu University , Fukuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"key":"2023092217013348800_R1","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1302\/0301-620X.90B12.21198","article-title":"Osteotomies around the knee: patient selection, stability of fixation and bone healing in high tibial osteotomies","volume":"90","author":"Brinkman","year":"2008","journal-title":"J Bone Joint Surg Br"},{"key":"2023092217013348800_R2","doi-asserted-by":"crossref","first-page":"61","DOI":"10.5792\/ksrr.2012.24.2.61","article-title":"High tibial osteotomy","volume":"24","author":"Lee","year":"2012","journal-title":"Knee Surg Relat Res"},{"key":"2023092217013348800_R3","doi-asserted-by":"crossref","first-page":"977","DOI":"10.2106\/00004623-198870070-00004","article-title":"Proximal tibial osteotomy in patients who are fifty years old or less. A long-term follow-up study","volume":"70","author":"Holden","year":"1988","journal-title":"J Bone Joint Surg Am"},{"key":"2023092217013348800_R4","doi-asserted-by":"crossref","first-page":"527","DOI":"10.3109\/17453678909150116","article-title":"Function after tibial osteotomy for medial gonarthrosis below aged 50 years","volume":"60","author":"Odenbring","year":"1989","journal-title":"Acta Orthop Scand"},{"key":"2023092217013348800_R5","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-03259-y","article-title":"Older age increases the risk of revision and perioperative complications after high tibial osteotomy for unicompartmental knee osteoarthritis","volume":"11","author":"Lee","year":"2021","journal-title":"Sci Rep"},{"key":"2023092217013348800_R6","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1007\/s00167-008-0609-8","article-title":"Simultaneous bilateral opening-wedge high tibial osteotomy with early full weight-bearing exercise","volume":"16","author":"Takeuchi","year":"2008","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2023092217013348800_R7","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.arthro.2008.08.015","article-title":"Medial opening wedge high tibial osteotomy with early full weight bearing","volume":"25","author":"Takeuchi","year":"2009","journal-title":"Arthroscopy"},{"key":"2023092217013348800_R8","doi-asserted-by":"crossref","first-page":"3670","DOI":"10.1007\/s00167-016-4225-8","article-title":"Early weight bearing versus delayed weight bearing in medial opening wedge high tibial osteotomy: a randomized controlled trial","volume":"25","author":"Lansdaal","year":"2017","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2023092217013348800_R9","doi-asserted-by":"crossref","first-page":"e655","DOI":"10.1016\/j.eats.2019.02.011","article-title":"Distal tibial tuberosity arc osteotomy in open-wedge proximal tibial osteotomy to prevent patella infra","volume":"8","author":"Akiyama","year":"2019","journal-title":"Arthrosc Tech"},{"key":"2023092217013348800_R10","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1007\/s00167-019-05596-y","article-title":"Distal tuberosity osteotomy in open-wedge high tibial osteotomy does not exacerbate patellofemoral osteoarthritis on arthroscopic evaluation","volume":"28","author":"Horikawa","year":"2020","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2023092217013348800_R11","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1007\/s00167-015-3847-6","article-title":"Age does not affect the clinical and radiological outcomes after open-wedge high tibial osteotomy","volume":"25","author":"Goshima","year":"2017","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2023092217013348800_R12","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1007\/s00167-012-2016-4","article-title":"Age does not influence the clinical outcome after high tibial osteotomy","volume":"21","author":"Kohn","year":"2013","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2023092217013348800_R13","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1007\/s00264-017-3517-z","article-title":"Survivorship of medial opening wedge high tibial osteotomy in the elderly: two to ten years of follow up","volume":"41","author":"Ruangsomboon","year":"2017","journal-title":"Int Orthop"},{"key":"2023092217013348800_R14","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.jos.2018.12.022","article-title":"Patient reported outcomes after high tibial osteotomy show comparable results at different ages in the mid-term to long-term follow-up","volume":"24","author":"Kuwashima","year":"2019","journal-title":"J Orthop Sci"},{"key":"2023092217013348800_R15","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/S0140-6736(17)30059-4","article-title":"The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study","volume":"389","author":"Bayliss","year":"2017","journal-title":"Lancet"},{"key":"2023092217013348800_R16","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1016\/j.joca.2017.08.017","article-title":"Changes in biomechanical risk factors for knee osteoarthritis and their association with 5-year clinically important improvement after limb realignment surgery","volume":"25","author":"Birmingham","year":"2017","journal-title":"Osteoarthritis Cartilage"},{"key":"2023092217013348800_R17","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.jor.2020.01.042","article-title":"The influence of post-operative knee coronal alignment parameters on long-term patient-reported outcomes after closed-wedge high tibial osteotomy","volume":"20","author":"Goto","year":"2020","journal-title":"J Orthop"},{"key":"2023092217013348800_R18","doi-asserted-by":"crossref","DOI":"10.1177\/2325967120967964","article-title":"Factors associated with patient satisfaction after opening-wedge high tibial osteotomy","volume":"8","author":"Goshima","year":"2020","journal-title":"Orthop J Sports Med"},{"key":"2023092217013348800_R19","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2474-12-46","article-title":"Closing-wedge high tibial osteotomy: survival and risk factor analysis at long-term follow up","volume":"12","author":"Efe","year":"2011","journal-title":"BMC Musculoskelet Disord"},{"key":"2023092217013348800_R20","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1177\/0363546513516577","article-title":"Medial opening wedge high tibial osteotomy for medial compartment overload\/arthritis in the varus knee: prognostic factors","volume":"42","author":"Bonasia","year":"2014","journal-title":"Am J Sports Med"},{"key":"2023092217013348800_R21","doi-asserted-by":"crossref","first-page":"879","DOI":"10.2106\/JBJS.18.00642","article-title":"Preoperative radiographic osteoarthritis severity modifies the effect of preoperative pain on pain\/function after total knee arthroplasty: results at 1 and 2 years postoperatively","volume":"101","author":"van de Water","year":"2019","journal-title":"J Bone Joint Surg Am"},{"key":"2023092217013348800_R22","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1055\/s-0038-1635114","article-title":"More severe preoperative Kellgren-Lawrence grades of knee osteoarthritis were partially associated with better postoperative patient-reported outcomes in TKA patients","volume":"32","author":"Hoorntje","year":"2019","journal-title":"J Knee Surg"},{"key":"2023092217013348800_R23","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s10195-010-0086-y","article-title":"Key factors in determining surgical timing of total knee arthroplasty in osteoarthritic patients: age, radiographic severity, and symptomatic severity","volume":"11","author":"Chang","year":"2010","journal-title":"J Orthop Traumatol"},{"key":"2023092217013348800_R24","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.arth.2017.08.035","article-title":"Sports participation in patients after total hip arthroplasty vs periacetabular osteotomy: a propensity score-matched Asian cohort study","volume":"33","author":"Hara","year":"2018","journal-title":"J Arthroplasty"},{"key":"2023092217013348800_R25","doi-asserted-by":"crossref","DOI":"10.1177\/2309499019895636","article-title":"Differences in patient-reported outcomes between medial opening-wedge high tibial osteotomy and total knee arthroplasty","volume":"28","author":"Matsumoto","year":"2020","journal-title":"J Orthop Surg (Hong Kong)"},{"key":"2023092217013348800_R26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.artd.2020.11.010","article-title":"Total knee arthroplasty is superior to open wedge high tibial osteotomy in terms of pain relief for patients with osteoarthritis","volume":"7","author":"Hamahashi","year":"2021","journal-title":"Arthroplast Today"},{"key":"2023092217013348800_R27","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1177\/0363546508330149","article-title":"Lysholm score and Tegner activity level in individuals with normal knees","volume":"37","author":"Briggs","year":"2009","journal-title":"Am J Sports Med"},{"key":"2023092217013348800_R28","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1007\/s11999-014-3650-6","article-title":"The KSS 2011 reflects symptoms, physical activities, and radiographic grades in a Japanese population","volume":"473","author":"Taniguchi","year":"2015","journal-title":"Clin Orthop Relat Res"},{"key":"2023092217013348800_R29","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1080\/17453670710015021","article-title":"Survival of closing-wedge high tibial osteotomy: good outcome in men with low-grade osteoarthritis after 10-16 years","volume":"79","author":"van Raaij","year":"2008","journal-title":"Acta Orthop"},{"key":"2023092217013348800_R30","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1007\/s00167-018-5121-1","article-title":"Radiological grading of osteoarthritis on Rosenberg view has a significant correlation with clinical outcomes after medial open-wedge high-tibial osteotomy","volume":"27","author":"Nha","year":"2019","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2023092217013348800_R31","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.knee.2021.02.031","article-title":"Effect of osteoarthritis severity on survival and clinical outcomes after high tibial osteotomy","volume":"29","author":"Kuwashima","year":"2021","journal-title":"Knee"},{"key":"2023092217013348800_R32","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1007\/s00167-019-05350-4","article-title":"Hybrid closed wedge high tibial osteotomy improves patellofemoral joint congruity compared with open wedge high tibial osteotomy","volume":"27","author":"Ishimatsu","year":"2019","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"2023092217013348800_R33","doi-asserted-by":"crossref","first-page":"e431","DOI":"10.1016\/j.eats.2014.04.004","article-title":"A novel closed-wedge high tibial osteotomy procedure to treat osteoarthritis of the knee: hybrid technique and rehabilitation measures","volume":"3","author":"Takeuchi","year":"2014","journal-title":"Arthrosc Tech"},{"key":"2023092217013348800_R34","doi-asserted-by":"crossref","DOI":"10.1186\/s40634-020-00247-5","article-title":"Tibial condylar valgus osteotomy - indications and technique","volume":"7","author":"Kuwashima","year":"2020","journal-title":"J Exp Orthop"},{"key":"2023092217013348800_R35","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.knee.2012.12.012","article-title":"Survival and clinical outcome of isolated high tibial osteotomy and combined biological knee reconstruction","volume":"20","author":"Harris","year":"2013","journal-title":"Knee"},{"key":"2023092217013348800_R36","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s00264-009-0889-8","article-title":"Results of high tibial osteotomy: review of the literature","volume":"34","author":"Amendola","year":"2010","journal-title":"Int Orthop"},{"key":"2023092217013348800_R37","doi-asserted-by":"crossref","first-page":"771","DOI":"10.2106\/JBJS.18.00980","article-title":"Risk of revision following total knee arthroplasty or high tibial osteotomy: a nationwide propensity-score-matched study","volume":"101","author":"Yoon","year":"2019","journal-title":"J Bone Joint Surg Am"}],"container-title":["Modern Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/mr\/advance-article-pdf\/doi\/10.1093\/mr\/roac052\/44251546\/roac052.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mr\/article-pdf\/33\/3\/623\/51715084\/roac052.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mr\/article-pdf\/33\/3\/623\/51715084\/roac052.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T17:31:13Z","timestamp":1695403873000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mr\/article\/33\/3\/623\/6598766"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,2]]},"references-count":37,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,6,2]]},"published-print":{"date-parts":[[2023,4,13]]}},"URL":"https:\/\/doi.org\/10.1093\/mr\/roac052","relation":{},"ISSN":["1439-7595","1439-7609"],"issn-type":[{"value":"1439-7595","type":"print"},{"value":"1439-7609","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,5,1]]},"published":{"date-parts":[[2022,6,2]]}}}