{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T05:06:36Z","timestamp":1764047196770,"version":"3.37.3"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T00:00:00Z","timestamp":1678924800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,26]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>The aim is to evaluate the prevention and development of cervical cancer in systemic lupus erythematosus (SLE) patients in Japan and its background based on a questionnaire survey.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The questionnaire was handed to 460 adult female SLE patients at 12 medical institutions. The participants were grouped by age, and data related to their human papillomavirus vaccination status, age at first coitus, cervical cancer screening, and diagnosis of cervical cancer were analysed.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 320 responses were received. Patients aged 35\u201354\u2009years included a higher proportion of patients whose age at first coitus was &amp;lt;20\u2009years. This group also showed a higher rate of cervical cancer\/dysplasia. Only nine patients had a human papillomavirus vaccination history. Adequate frequency of cervical cancer screening was slightly higher (52.1%) among SLE patients than in the Japanese general population. However, 23% of the patients had never undergone examination, primarily because of a feeling of troublesome. The incidence of cervical cancer was significantly higher among SLE patients. One reason for this may be associated with the use of immunosuppressants, although the difference was not significant.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>SLE patients are at a higher risk of cervical cancer and dysplasia. Rheumatologists should proactively recommend vaccination and screening examinations for SLE female patients.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/road028","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T15:09:43Z","timestamp":1678979383000},"page":"352-358","source":"Crossref","is-referenced-by-count":3,"title":["Questionnaire survey on the prevention and development of cervical cancer in patients with systemic lupus erythematosus in Japan"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7122-4832","authenticated-orcid":false,"given":"Yohko","family":"Murakawa","sequence":"first","affiliation":[{"name":"Department of Internal Medicine III, Shimane University , Izumo, Japan"},{"name":"Department of Rheumatology, Shimane University Faculty of Medicine , Izumo, Japan"},{"name":"Department of Rheumatology, Tamatsukuri Hospital , Matsue, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Dobashi","sequence":"additional","affiliation":[{"name":"Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa University , Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Shimane University Faculty of Medicine , Izumo, Japan"},{"name":"National Hospital Organization Hamada Medical Center , Hamada, Japan"},{"name":"Division of Rheumatology, Masuda Medical Association Hospital , Masuda, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"Rheumatic Disease Center, Kurashiki Medical center , Kurashiki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Okazaki","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine and Rheumatology, Department of Multidisciplinary Internal Medicine, Faculty of Medicine, Tottori University , Yonago, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Tottori Prefecture Central Hospital , Tottori, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayuko","family":"Moriyama","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Shimane University Faculty of Medicine , Izumo, Japan"},{"name":"Division of Rheumatology, Oda Municipal Hospital , Oda, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoko","family":"Sugiura","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Shimane University Faculty of Medicine , Izumo, Japan"},{"name":"Sugiura Clnic , Izumo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikuko","family":"Onishi","sequence":"additional","affiliation":[{"name":"Utazu Hospital , Kagawa, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Honda","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Shimane University Faculty of Medicine , Izumo, Japan"},{"name":"Division of Rheumatology, Oda Municipal Hospital , Oda, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihiro","family":"Nagamura","sequence":"additional","affiliation":[{"name":"Department of Allergy & Rheumatology, Shimane Central Hospital , Izumo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Yoshioka","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Shimane University Faculty of Medicine , Izumo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiko","family":"Minamoto","sequence":"additional","affiliation":[{"name":"Department of Gynecology, Faculty of Medicine Shimane University , Izumo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,3,16]]},"reference":[{"key":"2024022623081222400_R1","first-page":"17","article-title":"Cervical human papillomavirus infection and intraepithelial neoplasia: a review","volume":"21","author":"Mitchell","year":"1996","journal-title":"J Natl Cancer Inst Monogr"},{"key":"2024022623081222400_R2","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1136\/annrheumdis-2013-204993","article-title":"Risk of high-grade cervical dysplasia and cervical cancer in women with systemic inflammatory diseases: a population-based cohort study","volume":"74","author":"Kim","year":"2015","journal-title":"Ann Rheum 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literature","volume":"13","author":"Zard","year":"2014","journal-title":"Autoimmun Rev"},{"key":"2024022623081222400_R6","doi-asserted-by":"crossref","DOI":"10.1186\/s13075-018-1760-3","article-title":"The risks of cancer development in systemic lupus erythematosus (SLE) patients: a systematic review and meta-analysis","volume":"20","author":"Song","year":"2018","journal-title":"Arthritis Res Ther"},{"key":"2024022623081222400_R7","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1177\/0961203319826672","article-title":"Systemic lupus erythematosus is a risk factor for cancer: a nationwide population-based study in Korea","volume":"28","author":"Bae","year":"2019","journal-title":"Lupus"},{"key":"2024022623081222400_R8","first-page":"613","article-title":"Cervical neoplasia in systemic lupus erythematosus: a nationwide 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