{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T13:59:59Z","timestamp":1788011999006,"version":"build-2784847793"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T00:00:00Z","timestamp":1695859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to investigate the gender-based differences in idiopathic inflammatory myopathies (IIMs), with a particular focus on patient-reported outcomes, utilizing the data obtained through the international COVID-19 vaccination in autoimmune disease e-survey.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patient-reported outcomes including fatigue, pain, and physical function were extracted from the COVID-19 vaccination in autoimmune disease database and compared between genders, adjusting for demographics and IIM subgroups by multivariable analysis. Inclusion body myositis (IBM) was analysed separately because of the substantial differences in outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1197 complete responses from patients with IIMs as of 31 August 2021 were analysed. Seventy percent were women. Women were younger (58 [48\u201368] vs. 69 [58\u201375] years old, median [interquartile range], P\u2009&amp;lt;\u2009.001) and were more likely to suffer from autoimmune multimorbidity, defined as three or more autoimmune diseases in an individual patient (11.4% vs. 2.8%, P\u2009&amp;lt;\u2009.001). In non-IBM IIMs, fatigue visual analogue scale scores were higher in women (5 [3\u20137] vs. 4 [2\u20136], median [interquartile range], P\u2009=\u2009.004), whereas no significant gender-based differences were noted in IBM. Multivariable analysis in non-IBM IIMs revealed that women, residence in high-income countries, overlap myositis, and autoimmune multimorbidity were independently associated with increased fatigue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Women with IIMs suffer from autoimmune multimorbidity and experience increased fatigue compared to men.<\/jats:p><\/jats:sec>","DOI":"10.1093\/mr\/road094","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T19:49:48Z","timestamp":1695930588000},"page":"756-766","source":"Crossref","is-referenced-by-count":3,"title":["Gender differences in\u00a0patient experience in\u00a0idiopathic inflammatory myopathies: Subanalysis from the COVAD dataset"],"prefix":"10.1093","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3590-1637","authenticated-orcid":false,"given":"Akira","family":"Yoshida","sequence":"first","affiliation":[{"name":"Department of Allergy and Rheumatology, 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Rheumatology, Mayo Clinic , Rochester, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parikshit","family":"Sen","sequence":"additional","affiliation":[{"name":"Maulana Azad Medical College , New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James B","family":"Lilleker","sequence":"additional","affiliation":[{"name":"Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester , Manchester, UK"},{"name":"Neurology, Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust , Salford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishwesh","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Mahatma Gandhi Mission Medical College , Navi Mumbai, 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Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mrudula","family":"Joshi","sequence":"additional","affiliation":[{"name":"Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals , Pune, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamer","family":"Gheita","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University , Cairo, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babur","family":"Salim","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Fauji Foundation Hospital , Rawalpindi, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsvetelina","family":"Velikova","sequence":"additional","affiliation":[{"name":"Medical Faculty, Sofia University St. Kliment Ohridski , Sofia, Bulgaria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham Edgar","family":"Gracia-Ramos","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, General Hospital, National Medical Center \u2018La Raza\u2019, Instituto Mexicano del Seguro Social , Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Parodis","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital , Stockholm, Sweden"},{"name":"Department of Rheumatology, Faculty of Medicine and Health, \u00d6rebro University , \u00d6rebro, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Nikiphorou","sequence":"additional","affiliation":[{"name":"Centre for Rheumatic Diseases, King\u2019s College London , London, UK"},{"name":"Rheumatology Department, King\u2019s College Hospital , London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tulika","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Center for Outcomes Research, Department of Internal Medicine, University of Illinois College of Medicine Peoria , Peoria, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai Lyn","family":"Tan","sequence":"additional","affiliation":[{"name":"NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust , Leeds, UK"},{"name":"Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds , Leeds, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvind","family":"Nune","sequence":"additional","affiliation":[{"name":"Southport and Ormskirk Hospital NHS Trust , Southport, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Cavagna","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Fondazione I.R.C.C.S. Policlinico San Matteo , Pavia, Italy"},{"name":"Rheumatology Unit, Dipartimento di Medicine Interna e Terapia Medica, Universit\u00e0 degli studi di Pavia , Pavia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel A","family":"Saavedra","sequence":"additional","affiliation":[{"name":"Departamento de Reumatolog\u00eda Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro M\u00e9dico Nacional La Raza, IMSS , Mexico City, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel Katsuyuki","family":"Shinjo","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo , Sao Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelly","family":"Ziade","sequence":"additional","affiliation":[{"name":"Rheumatology Department, Saint-Joseph University , Beirut, Lebanon"},{"name":"Rheumatology Department, Hotel-Dieu de France Hospital , Beirut, 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