{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T07:23:53Z","timestamp":1775892233146,"version":"3.50.1"},"reference-count":130,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,3,30]],"date-time":"2024-03-30T00:00:00Z","timestamp":1711756800000},"content-version":"vor","delay-in-days":70,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:p>Lupus remains a disease with a low prioritisation in the national agendas of many countries in Latin America, the Middle East, and Asia-Pacific, where there is a dearth of rheumatologists and limited access to new or even standard lupus treatments. There is thus an important need for education, advocacy, and outreach to prioritise lupus in these regions to ensure that patients receive the care they need. This article reviews some of the specific challenges facing the care and management of people with lupus in these regions and suggests strategies for improving patient outcomes. Specifically, we review and discuss (with a focus on the aforementioned regions) the epidemiology of lupus; economic costs, disease burden, and effects on quality of life; barriers to care related to disease assessment; barriers to effective treatment, including limitations of standard treatments, high glucocorticoid use, inadequate access to new treatments, and low adherence to medications; and strategies to improve lupus management and patient outcomes. We hope that this represents a call to action to come together and act now for the lupus community, policymakers, health authorities, and healthcare professionals to improve lupus management and patient outcomes in Latin America, the Middle East, and Asia-Pacific.<\/jats:p>","DOI":"10.1093\/mr\/roae001","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T21:21:46Z","timestamp":1711488106000},"page":"655-669","source":"Crossref","is-referenced-by-count":7,"title":["Opportunities and challenges of lupus care in Latin America, the Middle East, and Asia-Pacific: A call to action"],"prefix":"10.1093","volume":"34","author":[{"given":"Eduardo","family":"Mysler","sequence":"first","affiliation":[{"name":"Organizaci\u00f3n Medica de Investigaci\u00f3n , Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odirlei Andre","family":"Monticielo","sequence":"additional","affiliation":[{"name":"Rheumatology Division, Hospital de Cl\u00ednicas de Porto Alegre, Universidade Federal do Rio Grande do Sul , Porto Alegre, Rio Grande do Sul, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim Abdulrazaq","family":"Al-Homood","sequence":"additional","affiliation":[{"name":"Medical Specialties Department, Rheumatology Section, King Fahad Medical City , Riyadh, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chak Sing","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong , Pokfulam, Hong Kong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heselynn","family":"Hussein","sequence":"additional","affiliation":[{"name":"Subang Jaya Medical Centre , Subang Jaya, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Hsing","family":"Chen","sequence":"additional","affiliation":[{"name":"Taichung Veterans General Hospital , Taichung, Taiwan, Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,1,20]]},"reference":[{"key":"2024070612130245500_R1","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1111\/imj.15448","article-title":"Systemic lupus erythematosus: a clinical update","volume":"51","author":"Connelly","year":"2021","journal-title":"Intern Med J"},{"key":"2024070612130245500_R2","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/s41584-021-00668-1","article-title":"Global epidemiology of systemic lupus erythematosus","volume":"17","author":"Barber","year":"2021","journal-title":"Nat Rev Rheumatol"},{"key":"2024070612130245500_R3","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/nrrheum.2016.137","article-title":"The global burden of SLE: prevalence, health disparities and socioeconomic impact","volume":"12","author":"Carter","year":"2016","journal-title":"Nat Rev 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