{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T02:17:50Z","timestamp":1777601870591,"version":"3.51.4"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T00:00:00Z","timestamp":1712620800000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Chronic diseases impact people\u2019s quality of life (QoL). Beh\u00e7et\u2019s disease (BD) is a multisystemic chronic disease characterized by vasculitis of various vessels. We aimed to assess QoL in paediatric BD (PEDBD) patients and their parents.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We conducted a cross-sectional study from June to December 2022, including PEDBD patients meeting classification criteria. We recorded clinical characteristics and assessed QoL using PedsQL for patients and WHOQOL-Bref for parents.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A study of 38 patients (60.5% girls, 39.5% boys), median age 15.5 years (range 10\u201317), with oral aphthae and various mucocutaneous symptoms: genital ulcers (78.9%), pseudofolliculitis (76.3%), erythema nodosum (23.6%), and some with uveitis (13.1%), vascular (13.1%), neurological (10.5%), and gastrointestinal (5.2%) involvement. All were in remission under treatment. Median PedsQL scores: total 74.5 (range 40\u201394.8), physical health 76.5 (43\u2013100), psychosocial health 75 (25\u201392); 14 patients scored below cutoff. Girls had lower physical health scores (P\u2009=\u2009.004), and disease duration correlated negatively with PedsQL score (r\u2009=\u2009-0.648, P\u2009=\u2009.001). Median WHOQOL score for parents: 50 (25\u2013100), with 20 scoring below cutoff.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>One-third of PEDBD children and over half of their parents had low QoL. Disease duration and gender, as with many chronic illnesses, correlated with QoL in PEDBD.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roae031","type":"journal-article","created":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T05:10:07Z","timestamp":1712639407000},"page":"1226-1230","source":"Crossref","is-referenced-by-count":1,"title":["The relationship between Beh\u00e7et\u2019s disease and the quality of life for pediatric patients and their parents"],"prefix":"10.1093","volume":"34","author":[{"given":"Nihal","family":"\u015eahin","sequence":"first","affiliation":[{"name":"Department of Pediatric Rheumatology, Kocaeli University, Faculty of Medicine , Kocaeli,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunus E","family":"Bayrak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, Kocaeli University, Faculty of Medicine , Kocaeli,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafize E","family":"S\u00f6nmez","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, Kocaeli University, Faculty of Medicine , Kocaeli,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bet\u00fcl","family":"S\u00f6zeri","sequence":"additional","affiliation":[{"name":"Department of Pediatric Rheumatology, University of Health Sciences, \u00dcmraniye Research and Training Hospital , Istanbul,","place":["Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,4,1]]},"reference":[{"key":"2024110410413649200_R1","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1136\/annrheumdis-2015-208491","article-title":"Consensus classification criteria for paediatric Beh\u00e7et\u2019s disease from a prospective observational cohort: 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