{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:06:19Z","timestamp":1789664779626,"version":"4.0.1"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T00:00:00Z","timestamp":1723161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,21]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Baker\u2019s cyst (BC) is a complex complication of rheumatoid arthritis (RA), with a poor prognosis. This paper aimed to analyse the clinical features and risk factors for BC in patients with RA to assist clinicians in early warning and appropriate action.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The clinical features of the hospitalized RA patients with knee affected were analysed retrospectively. The R software was used for the statistical analysis, while logistic regression analyses were used to determine independent risk factors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 367 RA patients with knee affected were studied, and BC was diagnosed in 15.3% of them. The BC group exhibited a higher proportion of knee-only affected than the non-BC group (P\u2009&amp;lt;\u2009.05), while the attributes linked to disease activity exhibited no disparity. Logistic regression analyses selected two independent risk factors for BC: knee-only affected and anaemia. A total of 26.8% of patients with BC developed rupture, exhibiting a higher proportion of knee-only affected (P\u2009&amp;lt;\u2009.05), compared to those unruptured.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>The occurrence and rupture of BC in RA patients were significantly related to local inflammation, but not to systemic one. Incorporating local treatment may be a more advantageous option compared to solely relying on systemic therapy.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/mr\/roae063","type":"journal-article","created":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T17:58:14Z","timestamp":1723226294000},"page":"273-279","source":"Crossref","is-referenced-by-count":3,"title":["Clinical features and risk factors for Baker\u2019s cyst in patients with rheumatoid arthritis"],"prefix":"10.1093","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5849-2739","authenticated-orcid":false,"given":"Wan Lan","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Immunology, The Third Affiliated Hospital of Soochow University , Changzhou,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Third Affiliated Hospital of Soochow University , Changzhou,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bi Qing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine, The Third Affiliated Hospital of Soochow University , Changzhou,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Third Affiliated Hospital of Soochow University , Changzhou,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Third Affiliated Hospital of Soochow University , Changzhou,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Immunology, The Third Affiliated Hospital of Soochow University , Changzhou,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,8,9]]},"reference":[{"key":"2025030423303383600_R1","first-page":"300","article-title":"Ultrasound imaging for the rheumatologist XXVII. Sonographic assessment of the knee in patients with rheumatoid arthritis","volume":"28","author":"Riente","year":"2010","journal-title":"Clin Exp Rheumatol"},{"key":"2025030423303383600_R2","first-page":"633","article-title":"Baker\u2019s cyst in rheumatoid arthritis: an ultrasonographic study with a high resolution technique","volume":"13","author":"Andonopoulos","year":"1995","journal-title":"Clin Exp Rheumatol"},{"key":"2025030423303383600_R3","doi-asserted-by":"crossref","first-page":"843","DOI":"10.5535\/arm.2014.38.6.843","article-title":"Ruptured popliteal cyst diagnosed by ultrasound before evaluation for deep vein thrombosis","volume":"38","author":"Kim","year":"2014","journal-title":"Ann Rehabil Med"},{"key":"2025030423303383600_R4","article-title":"Ruptured Baker\u2019s cyst with compartment syndrome: an extremely unusual complication","volume":"2012","author":"Hamlet","year":"2012","journal-title":"BMJ Case Rep"},{"key":"2025030423303383600_R5","doi-asserted-by":"crossref","DOI":"10.2169\/internalmedicine.1754-18","article-title":"Ruptured Baker\u2019s cyst in rheumatoid arthritis","volume":"58","author":"Nakamura","year":"2019","journal-title":"Intern Med"},{"key":"2025030423303383600_R6","doi-asserted-by":"crossref","DOI":"10.1186\/s12891-018-2263-8","article-title":"Pseudothrombophlebitis syndrome in a rheumatoid arthritis patient with swollen calf and persistent itching: a case report","volume":"19","author":"Mulkoglu","year":"2018","journal-title":"BMC Musculoskelet Disord"},{"key":"2025030423303383600_R7","doi-asserted-by":"crossref","DOI":"10.1097\/RHU.0000000000001166","article-title":"Giant Baker cyst in a patient with rheumatoid arthritis","volume":"26","author":"Serfaty","year":"2020","journal-title":"J Clin Rheumatol"},{"key":"2025030423303383600_R8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/BF00181107","article-title":"Popliteal cysts and associated disorders of the knee. Critical review with MR imaging","volume":"19","author":"Sansone","year":"1995","journal-title":"Int Orthop"},{"key":"2025030423303383600_R9","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1007\/s10067-010-1483-6","article-title":"Pathology associated to the Baker\u2019s cysts: a musculoskeletal ultrasound study","volume":"29","author":"Liao","year":"2010","journal-title":"Clin Rheumatol"},{"key":"2025030423303383600_R10","article-title":"Popliteal cyst","volume":"67","author":"Delannoy","year":"2017","journal-title":"Rev Prat"},{"key":"2025030423303383600_R11","first-page":"179","article-title":"Prevalence and characteristics of complications of Baker cysts by MRI","volume":"201","author":"Molla Olmos","year":"2001","journal-title":"Rev Clin Esp"},{"key":"2025030423303383600_R12","article-title":"Giant Baker\u2019s cyst associated with rheumatoid arthritis","volume":"2017","author":"Adiyeke","year":"2017","journal-title":"Case Rep Orthop"},{"key":"2025030423303383600_R13","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1159\/000518792","article-title":"Baker\u2019s cyst with knee osteoarthritis: clinical and therapeutic implications","volume":"30","author":"Abate","year":"2021","journal-title":"Med Princ Pract"},{"key":"2025030423303383600_R14","doi-asserted-by":"crossref","first-page":"e678","DOI":"10.3928\/01477447-20140728-52","article-title":"Popliteal cysts: a current review","volume":"37","author":"Herman","year":"2014","journal-title":"Orthopedics"},{"key":"2025030423303383600_R15","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1007\/s10067-020-05049-9","article-title":"Profile of common inflammatory markers in treatment-naive patients with systemic rheumatic diseases","volume":"39","author":"Kim","year":"2020","journal-title":"Clin Rheumatol"},{"key":"2025030423303383600_R16","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1615\/JEnvironPatholToxicolOncol.2018025137","article-title":"Evaluation of antiarthritic activity of butanol fraction of Punica granatum Linn. RIND EXTRACT AGAINST Freund\u2019s complete adjuvant-induced arthritis in rats","volume":"37","author":"Gautam","year":"2018","journal-title":"J Environ Pathol Toxicol Oncol"},{"key":"2025030423303383600_R17","doi-asserted-by":"crossref","DOI":"10.1186\/s13018-022-03430-9","article-title":"Diagnostic accuracy of ultrasound for the assessment of Baker\u2019s cysts: a meta-analysis","volume":"17","author":"Liu","year":"2022","journal-title":"J Orthop Surg Res"},{"key":"2025030423303383600_R18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1003296","article-title":"Enhanced treatment strategies and distinct disease outcomes among autoantibody-positive and -negative rheumatoid arthritis patients over 25 years: a longitudinal cohort study in the Netherlands","volume":"17","author":"Matthijssen","year":"2020","journal-title":"PLoS Med"},{"key":"2025030423303383600_R19","article-title":"From rheumatoid factor to anti-citrullinated protein antibodies and anti-carbamylated protein antibodies for diagnosis and prognosis prediction in patients with rheumatoid arthritis","volume":"22","author":"Wu","year":"2021","journal-title":"Int J Mol Sci"},{"key":"2025030423303383600_R20","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1007\/s10067-019-04431-6","article-title":"Occurrence of anti-CCP2 and RF isotypes and their relation to age and disease severity among Sudanese patients with rheumatoid arthritis","volume":"38","author":"Elshafie","year":"2019","journal-title":"Clin Rheumatol"},{"key":"2025030423303383600_R21","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1515\/med-2021-0310","article-title":"Knee alterations in rheumatoid arthritis: comparison of US and MRI","volume":"16","author":"Xiao","year":"2021","journal-title":"Open Med"},{"key":"2025030423303383600_R22","doi-asserted-by":"crossref","DOI":"10.3390\/jcm11206078","article-title":"Clinical factors and the outcome of treatment with methotrexate in rheumatoid arthritis: role of rheumatoid factor, erosive disease and high level of erythrocyte sedimentation rate","volume":"11","author":"Majorczyk","year":"2022","journal-title":"J Clin Med"},{"key":"2025030423303383600_R23","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1007\/s10067-019-04873-y","article-title":"Inflammatory anemia may be an indicator for predicting disease activity and structural damage in Chinese patients with rheumatoid arthritis","volume":"39","author":"Chen","year":"2020","journal-title":"Clin Rheumatol"},{"key":"2025030423303383600_R24","doi-asserted-by":"crossref","first-page":"4445","DOI":"10.2147\/JIR.S327465","article-title":"Erythroferrone expression in anemic rheumatoid arthritis patients: is it disordered iron trafficking or disease activity?","volume":"14","author":"Youssef","year":"2021","journal-title":"J Inflamm Res"},{"key":"2025030423303383600_R25","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1002\/acr.23427","article-title":"Low hemoglobin and radiographic damage progression in early rheumatoid arthritis: secondary analysis from a phase III trial","volume":"70","author":"Moller","year":"2018","journal-title":"Arthritis Care Res"},{"key":"2025030423303383600_R26","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.semarthrit.2017.03.001","article-title":"Clinical meaning and implications of serum hemoglobin levels in patients with rheumatoid arthritis","volume":"47","author":"Padjen","year":"2017","journal-title":"Semin Arthritis Rheum"},{"key":"2025030423303383600_R27","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3109\/s10165-002-0222-5","article-title":"Anterior tibial compartment syndrome following rupture of a popliteal cyst","volume":"13","author":"Ushiyama","year":"2003","journal-title":"Mod Rheumatol"},{"key":"2025030423303383600_R28","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1007\/s00296-019-04278-9","article-title":"Successful arthroscopic treatment of refractory and complicated popliteal cyst associated with rheumatoid arthritis in combination with osteoarthritis: case series and literature review","volume":"39","author":"Yang","year":"2019","journal-title":"Rheumatol Int"},{"key":"2025030423303383600_R29","doi-asserted-by":"crossref","first-page":"772","DOI":"10.3109\/14397595.2015.1008779","article-title":"Treatment of popliteal cysts via arthroscopic enlargement of unidirectional valvular slits","volume":"25","author":"Ohishi","year":"2015","journal-title":"Mod Rheumatol"},{"key":"2025030423303383600_R30","first-page":"64","article-title":"Giant Baker\u2019s cyst treated with intralessional methotrexate","volume":"81","author":"Hofmann-Gonzalez","year":"2013","journal-title":"Cir Cir"},{"key":"2025030423303383600_R31","doi-asserted-by":"crossref","first-page":"3466","DOI":"10.1016\/j.ejrad.2012.05.015","article-title":"Ultrasound guided percutaneous treatment and follow-up of Baker\u2019s cyst in knee osteoarthritis","volume":"81","author":"Koroglu","year":"2012","journal-title":"Eur J Radiol"},{"key":"2025030423303383600_R32","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s10067-011-1909-9","article-title":"Longitudinal ultrasound and clinical follow-up of Baker\u2019s cysts injection with steroids in knee osteoarthritis","volume":"31","author":"Bandinelli","year":"2012","journal-title":"Clin Rheumatol"}],"container-title":["Modern Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/mr\/advance-article-pdf\/doi\/10.1093\/mr\/roae063\/58943134\/roae063.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mr\/article-pdf\/35\/2\/273\/58943134\/roae063.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/mr\/article-pdf\/35\/2\/273\/58943134\/roae063.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T23:30:45Z","timestamp":1741131045000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mr\/article\/35\/2\/273\/7730392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,9]]},"references-count":32,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,8,9]]},"published-print":{"date-parts":[[2025,2,21]]}},"URL":"https:\/\/doi.org\/10.1093\/mr\/roae063","relation":{},"ISSN":["1439-7595","1439-7609"],"issn-type":[{"value":"1439-7595","type":"print"},{"value":"1439-7609","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,3]]},"published":{"date-parts":[[2024,8,9]]}}}